The Worm Whisperer

Could Chondroitin Sulphate be the missing link in parasite eradication?

Chondroitin sulfate plays a crucial role in the formation of human mucin due to its unique chemical and structural properties. Mucins are a class of high-molecular-weight glycoproteins that are vital components of various bodily secretions, such as mucus, which line and protect the epithelial surfaces of many organs and tissues.

Chondroitin sulfate, a complex polysaccharide, is composed of repeating disaccharide units containing glucuronic acid and N-acetylgalactosamine. It is one of the major glycosaminoglycans (GAGs) found in the extracellular matrix of connective tissues, including those in the respiratory, gastrointestinal, and reproductive systems.

In the context of mucin production, chondroitin sulfate acts as a critical building block during the biosynthesis and assembly of mucin molecules. It is incorporated into the core protein structure of mucins, providing structural stability and influencing their viscoelastic properties. Chondroitin sulfate contributes to the extended structure of mucins, allowing them to form large, highly hydrated networks that contribute to the gel-like consistency of mucus.

Moreover, chondroitin sulfate serves as a key determinant in determining the physiological properties of mucins. The negatively charged sulfate groups present in chondroitin sulfate contribute to the overall negative charge of mucins, influencing their interaction with other molecules, such as ions, proteins, and pathogens. This charge-based interaction is crucial for mucins' ability to act as a barrier, preventing the pe*******on of harmful substances, pathogens, and toxins into the underlying tissues.

Furthermore, chondroitin sulfate also plays a role in the regulation of mucin secretion. It has been found to modulate the expression and release of mucins by influencing the activity of various signaling pathways involved in the synthesis and secretion of these glycoproteins. By regulating mucin production, chondroitin sulfate helps maintain the protective properties of mucins, supporting the health and function of epithelial surfaces.

In summary, chondroitin sulfate is an essential component in the creation of human mucin. Its incorporation into the mucin structure provides stability, contributes to the gel-like consistency, influences the interaction with other molecules, and regulates mucin secretion. These roles are crucial for the proper functioning of mucins in protecting and maintaining the integrity of various tissues and organs throughout the body.
Which means that the use of Chondroitin Sulphate when working with any parasite eradication protocols may need to be considered.

Another part to the picture is:
The Role of Mucins in Host–Parasite
Interactions. Part I – Protozoan Parasites
S.J. Hicks, G. Theodoropoulos, S.D. Carrington and A.P. Corfield
https://www.academia.edu/21203067/The_Role_of_Mucins_in_Host_Parasite_Interactions_Part_I_Protozoan_Parasites?auto=download&email_work_card=download-paper

A fabulous read if anyone is interested

They state that "Parasite-derived mucin-like molecules might be involved in parasite attachment to and invasion of host cells. In addition, parasites might secrete mucin-degrading enzymes, enabling the pe*******on of protective mucus gels that overlie the mucosal surfaces of their potential hosts. Furthermore, they
might generate binding ligands on the membrane-bound
mucins of host cells by using specific glycosidases. It is possible that host mucins and mucin-like molecules prevent the
establishment of parasites or facilitate parasite expulsion.
They might also serve as a source of metabolic energy and
adhesion ligands for those parasites adapted to exploit them.
Sally Hicks and colleagues here review the biochemical
properties of mucins and mucin-like molecules in relation to
interactions (established and putative) between protozoan
parasites and their hosts."

I often see low iron in many patients who have long term parasite issues. One of my favorite products to use contains lactoferrin. Addressing some ones underlying nutritional deficiencies are paramount to reducing reinfection risk.
This is a great article: https://www.academia.edu/17801683/Antifungal_and_Antiparasitic_Activities_of_Lactoferrin?auto=download&email_work_card=download-paper
Abstract: The first function attributed to lactoferrin, an iron-binding protein belonging to the non-immune natural defense's, was antimicrobial activity related to its capability of sequestering iron. Many other antimicrobial and antiviral
functions have been ascribed to lactoferrin. In vitro activity towards human pathogenic fungi on the part of both human
and bovine lactoferrin has been well documented as well. The antifungal activity appears to be related to lactoferrin interference with the fungal cell surface rather than iron deprivation and some host-mediated mechanisms of action cannot be ruled out. Lactoferrin also displays anti-parasitic activity, although the molecular mechanisms of such activity are even
more complex.

Pinworm eggs are usually laid at night whilst the person sleeps around the a**s and/or va**na. These eggs are accompanied by an irritant mucus, which causes intense pruritus and scratching. Which is why we suggest the use of a barrier cream.
Some common barrier creams that are used and why they are no good is:
Coconut oil - as this absorbs into the skin and therefore fails to offer the correct barrier.
Vasoline - Main ingredient is Petroleum Jelly and it has been tied to Vaginal Infection Risk. Aside from the fact that putting chemicals on intimate areas are not a great idea.
https://www.webmd.com/women/news/20130308/petroleum-jelly-tied-to-va**nal-infection-risk-in-study

Need help choosing a barrier cream that is right for you? Drop us a line

The use of an appropriate barrier cream over the a**s is vital as part of your eradication protocol. This ensures that they do not have a chance to migrate to other areas like the urogenital tract easily and remain in the bowel for ease of eradication. Remember to apply it chunky! Think of it like you are closing a door. So a thin covering will not do! Also using oils like coconut oil will not do the job. Have a look at the barrier cream on the website as it’s been custom made to help with this issue.

https://thewormwhisperer.com.au/products/ariya-purity-bum-barrier-cream-60g