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How Psilocybin Impacts the Human Brain
Overview:
Psilocybin, found in magic mushrooms, has shown promising results in treating mental health issues like depression and anxiety. Researchers conducted a study to understand how psilocybin affects brain function.
Key Findings:
Brain Connectivity:
A single dose of psilocybin significantly alters brain connectivity.
It disrupts the normal synchronization of brain regions, especially affecting the default mode network (DMN), which is involved in our sense of self and time.
Therapeutic Effects:
The changes in brain connectivity are linked to the therapeutic effects of psilocybin.
These effects include symptom relief from depression, anxiety, and addiction, lasting from a few hours to several weeks.
Comparison with Methylphenidate (Ritalin):
Psilocybin's impact on brain connectivity is much greater than that of methylphenidate, a commonly used stimulant.
While both drugs increase heart rate, psilocybin causes more extensive and profound changes in brain function.
Persistent Changes:
Psilocybin causes long-lasting changes in brain connectivity, particularly between the hippocampus (involved in memory) and the DMN.
These changes may underpin the long-term mental health benefits observed with psilocybin.
Personal Experience:
The intensity of the psilocybin experience varies among individuals.
Participants reported feelings of connectedness, a sense of awe, and a loss of usual time and space perception during their psilocybin experience.
Practical Implications:
Understanding how psilocybin affects the brain can help develop better treatments for mental health disorders.
The study supports the use of psilocybin in controlled therapeutic settings to maximize its benefits and minimize risks.
Conclusion:
Psilocybin has a significant impact on brain function, leading to changes that could explain its therapeutic effects. These findings provide a scientific basis for the continued study and potential medical use of psilocybin in treating mental health issues.
How Psilocybin Impacts the Human Brain
Overview:
Psilocybin, found in magic mushrooms, has shown promising results in treating mental health issues like depression and anxiety. Researchers conducted a study to understand how psilocybin affects brain function.
Key Findings:
Brain Connectivity:
A single dose of psilocybin significantly alters brain connectivity.
It disrupts the normal synchronization of brain regions, especially affecting the default mode network (DMN), which is involved in our sense of self and time.
Therapeutic Effects:
The changes in brain connectivity are linked to the therapeutic effects of psilocybin.
These effects include symptom relief from depression, anxiety, and addiction, lasting from a few hours to several weeks.
Comparison with Methylphenidate (Ritalin):
Psilocybin's impact on brain connectivity is much greater than that of methylphenidate, a commonly used stimulant.
While both drugs increase heart rate, psilocybin causes more extensive and profound changes in brain function.
Persistent Changes:
Psilocybin causes long-lasting changes in brain connectivity, particularly between the hippocampus (involved in memory) and the DMN.
These changes may underpin the long-term mental health benefits observed with psilocybin.
Personal Experience:
The intensity of the psilocybin experience varies among individuals.
Participants reported feelings of connectedness, a sense of awe, and a loss of usual time and space perception during their psilocybin experience.
Practical Implications:
Understanding how psilocybin affects the brain can help develop better treatments for mental health disorders.
The study supports the use of psilocybin in controlled therapeutic settings to maximize its benefits and minimize risks.
Conclusion:
Psilocybin has a significant impact on brain function, leading to changes that could explain its therapeutic effects. These findings provide a scientific basis for the continued study and potential medical use of psilocybin in treating mental health issues.
source: nature.com
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The Spirit Molecule
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Terrence Mckenna
Archetypes, Individuation, and the Shadow: Carl Jung’s Enduring Psychedelic Influence Carl Jung's legacy is synchronizing with the resurgence of psychedelics. How can psychedelic practitioners put his teachings into practice?
Vital 4: Informational Session and Q+A, with David A free Vital Q+A: Register to speak with a member of the Vital team about our comprehensive psychedelic training for practitioners and professionals, beginning in September.
Vital 4: Informational Session and Q+A, with Diego A free Vital Q+A: Register to speak with a member of the Vital team about our comprehensive psychedelic training for practitioners and professionals, beginning in September.
Vital 4: Informational Session and Q+A, with Kyle A free Vital Q+A: Register to speak with a member of the Vital team about our comprehensive psychedelic training for practitioners and professionals, beginning in September.
Ayahuasca Traditions Abroad: Forest Medicine in the International Diaspora Using the Santo Daime movement as an example, this free webinar explores how ayahuasca traditions became a global phenomenon.
Chronic Pain and Inducing Neuroplasticity With Psychedelics Listen to this podcast about a case study in healing from chronic pain with psychedelics, featuring medically retired USAF JAG & Ops Resource Mgmt Specialist, Lynn Watkins; author, C.J. Spotswood, PMHNP; and REMAP Therapeutics Founder, Court Wing.
Vital 4: Informational Session and Q+A, with Johanna A free Vital Q+A: Register to speak with a member of the Vital team about our comprehensive psychedelic training for practitioners and professionals, beginning in September.
Interest In Microdosing Surges As Drug Policy Reforms Take Hold
🚀 Microdosing on the Rise! 🌿
Recent research from the University of California San Diego reveals a significant surge in interest in microdosing as drug policy reforms take hold across the United States. 📈 Google searches for terms like "microdosing" skyrocketed by 1,250% from 2015 to 2023! 🧠✨
What is Microdosing? 🤔
Microdosing involves taking tiny amounts of psychoactive substances, usually 1/20th to 1/5th of a regular dose. The goal? To enhance cognitive function, mood, and overall well-being without the intense effects. 🌱
Key Findings:
Search Trends: The study analyzed Google search data and found a massive increase in interest over the past eight years.
Policy Impact: This spike aligns with recent drug policy reforms that have eased restrictions on ma*****na and psychedelics in many states. 🌍
Why It Matters:
Microdosing is gaining popularity for its potential benefits without the drawbacks of full doses. As society becomes more open to these practices, we might see more research and acceptance in the future. 💡🔍
Stay tuned for more updates on this fascinating trend! 👀
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Microdosing as a Coaching Tool: Navigating the Path to Inner Truth Are you interested in exploring your inner truth through the mindful use of microdosing? Hosted by Tiffany Hurd and featuring a Q&A at the end, this webinar will cover: and more! Join us for this free webinar, whether you’re new to microdosing, have an established microdosing practice, are looking...
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Exploring Space with Fungi: The Vision of Paul Stamets
Few mycologists have achieved fame beyond their scientific field, but Paul Stamets stands at the pinnacle. Residing in the lush, fungi-rich environment of the Pacific Northwest, Stamets has made significant contributions to mycology over the past several decades. His groundbreaking work is perhaps best captured in his 2005 book Mycelium Running: How Mushrooms Can Help Save the World. Now, he’s looking beyond Earth, exploring how mushrooms might aid in the exploration of space.
The Astromycological Venture
In collaboration with NASA, Stamets is spearheading a new field called "astromycology." This venture explores how fungi can be utilized to construct extraterrestrial habitats and potentially terraform other planets. This isn’t Stamets’s first brush with speculative space science. Recently, he received an honor that many would consider just shy of a Nobel Prize: a Star Trek character named in his honor.
The Star Trek Connection
Stamets explains the serendipitous connection with Star Trek: "CBS reached out to me because the writers of Star Trek were stuck in a creative rut while working on Star Trek: Discovery. They had seen my TED Talk where I discussed the idea of terraforming planets with fungi," Stamets recalls.
"Star Trek has always emphasized inclusivity and diversity, which aligns perfectly with what I’ve learned as a mycologist: the resilience of our ecosystem comes from its biodiversity. Diversity is our strength," Stamets continues. "I explained that fungi were among the first organisms to colonize land, breaking down rocks and creating fertile soil, eventually giving rise to animal life about 650 million years ago. We are the descendants of these pioneering fungal networks."
When the Star Trek team expressed their gratitude, Stamets responded, "You can use all these ideas for free. I’m a Star Trek fan; I don't want anything in return. But I’ve always wanted to be known as the first astromycologist." They loved the term and decided to use it, marking a unique intersection between science fiction and real-world science.
Defining Astromycology
Stamets defines astromycology as a subset of astrobiology, which is the study of life beyond Earth. "Astromycology focuses on the study of fungi within the context of the universe’s biology. It’s inevitable that we’ll find fungi on other planets someday," he asserts.
The Potential of Fungi in Space Exploration
Stamets’s pioneering work in astromycology opens up thrilling possibilities for space travel and colonization. By harnessing the unique properties of fungi, we could potentially build sustainable habitats on other planets, transform alien landscapes, and even use psilocybin therapy to support astronauts’ mental health during long missions. This innovative approach highlights the versatility of fungi and underscores the importance of biodiversity and inclusivity in scientific progress.
As Paul Stamets continues to push the boundaries of mycology, his visionary work is sure to inspire future generations to consider fungi as a vital resource in the quest to explore and inhabit the cosmos.
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UC Berkeley To Enlist Human Subjects in Groundbreaking Psilocybin Study At the UC Berkeley Center for the Science of Psychedelics, researchers will examine human subjects to determine how psilocybin impacts our perception.