Drugs & pharmacy

استخدام ال glucocorticoids for 3 months or more
Ex prednisone 5mg / daily
Is a significant risk factor for osteoporosis
زي الفينادون شراب
ابيدون شراب
هوستاكورت اقراص
سولوبريد اقراص
و السبب هو أنه ب يزود إفراز ال ca ف البول

معلومه مهمه علي السريع
Allopurinol (zyloric tab)is the antihyperuricemic drug of choice in patients with a
history of urinary stones or impaired renal function, in patients who have
lymphoproliferative or myeloproliferative disorders and need pretreat-
ment with a xanthine oxidase inhibitor before initiation of cytotoxic
therapy to protect against acute uric acid nephropathy, and in patients
with gout who are overproducers of uric acid.

Adrenal corticosteroid inhibitors are drugs that inhibit key steps in the biosynthesis of hormones produced by the adrenal cortex, such as mineralocorticoids, glucocorticoids, estrogen and androgen. Adrenal corticosteroid inhibitors block one or more enzymes in the steroid synthesis pathway. They are used to treat Cushing's syndrome and some types of cancers. They are also used as diagnostic tools, such as in procedures to check pituitary function.
drugs
Aminoglutethimide
Osilodrostat
Metyrapone

Adrenal cortical steroids
Other names: corticosteroids, glucocorticoids, mineralocorticoids

Corticosteroids (adrenal cortical steroids) are natural hormones made by the adrenal cortex which are important in maintaining good health. There are two types of corticosteroids, the glucocorticoids and the mineralocorticoids.

Glucocorticoids e.g. cortisol and cortisone, are important for how the body responds to stress and also how it uses carbohydrate, fat and protein. Naturally occurring and synthetic glucocorticoids have very powerful anti-inflammatory effects and are used to treat conditions that involve inflammation. Glucocorticoids also decrease the body's immune response so are used to treat conditions when the immune system is over-reacting.

Mineralocorticoids e.g. aldosterone are necessary for regulation of salt and water in the body.

How they work
Natural corticosteriods are hormones which travel to different parts of the body to pass on messages to respond to the body’s changing needs. The corticosteriod messages act in body systems including stress response, immune response, inflammation levels, salt and water balance, and the breakdown of carbohydrates and protein.

The glucocorticoids activate the body’s anti-inflammatory response so are used to reduce swelling and pain caused by inflammation. Glucocorticoids also work to decrease the immune response and are therefore used to regulate the immune system when it is over-active in conditions like allergic reactions or autoimmune conditions.

Mineralocorticoids have their effect on the body’s salt and water balance so are used to correct any salt and water imbalance or as a supplement if the natural levels of aldosterone levels are low.
What they treat

Man made (synthetic) corticosteriods are used to treat a large number of conditions and symptoms. Corticosteriods are used as a replacement therapy when the body is not naturally producing enough of its own of natural corticosteriods. They are also used to treat conditions where there is inflammation, autoimmune conditions or allergy symptoms. Corticosteriods can be taken orally as a systemic treatment to treat the body as a whole or it can be applied to the affected area for a local effect as creams, inhalations, nasal sprays, eye drops, ear drops or injections. Examples of conditions they treat are

allergies

asthma

COPD

dermatitis

ulcerative colitis

Crohn’s disease

multiple sclerosis

nephrotic syndrome

adrenal insufficiency

inflammation

A

ACE inhibitors with thiazides is a combination medicine containing both an angiotensin-converting-enzyme inhibitor (ACE inhibitor) and a thiazide.

An ACE inhibitor blocks the angiotensin converting enzyme from converting angiotensin I to angiotensin II. This results in a decrease in angiotensin II causing vasodilation and therefore a reduction in blood pressure.

Thiazide diuretics decrease active re-absorption of sodium and chloride ions by inhibiting the sodium/chloride co-transporter in the distal convoluted tubule. This causes an increase in urine production (diuresis) and results in a decrease in blood volume and a reduction in blood pressure.
Drugs in pharmacy
1_sinopril co zestoretic ( Thiazide +lisinopril)
2_capozide farcopril plus (Thiazide+captopril)
3_ezapril co (enalapril+Thiazide)