Gene Company Limited

Gene Company is here at 2024 Hong Kong Inter-university postgraduate symposium in biochemical and life sciences!

Come say hi👋at our booth and chat with our product specialists about the latest technology🧬🦠 to explore the spark to advance your research.

WE offer the following fun engaging activities at the booth:
- Polar animal plush toy giveaway🐰🐻‍❄️🐧
- FREE Lab gloves trial
- FREE reagent kits and consumables samples
- On-going discount promotion on selected brands
- On-site technical discussion💡

Gene Company is here at 2024 Hong Kong Inter-university postgraduate symposium in biochemical and life sciences!

Come say hi👋at our booth and chat with our product specialists about the latest technology 🧬🦠to explore the spark to advance your research.

WE offer the following fun engaging activities at the booth:
- Polar animal plush toy giveaway 🐰🐻‍❄️🐧
- FREE Lab gloves trial
- FREE reagent kits and consumables samples
- On-going discount promotion on selected brands
- On-site technical discussion 💡

PacBio 2024 & SMRT Grant just opened for submissions. Apply if you'd like! It's a short, 100-word proposal. Submissions close on July 15, 2024.

If you are doing projects for full-length , shotgun read-based profiling, or shotgun metagenome assembly (MAGs), apply now to get FREE Phase Genomics ProxiMeta Hi-C with library prep and sequencing at Zymo Research Corp and SeqCenter.

Apply at https://programs.pacb.com/l/1652/2024-05-20/44mlb4?utm_source=Email&utm_medium=emailBlast&utm_term=textLink&utm_content=event-round-up&utm_campaign=2024-06-SMRT-Grant-Microbial-Genomics

🆕 Publication: Insights into Facioscapulohumeral Muscular Dystrophy (FSHD) 🧬

The latest study from University of California, Irvine uncovers that FSHD is linked to the abnormal de-repression of the transcription activator DUX4, affecting only a small percentage of cells. Traditional RNA-seq methods struggle to analyze multinucleated myotubes, but offers a breakthrough with its subcellular resolution capabilities.

This study provides comprehensive gene network profiling of multinucleated cells and identifies FSHD-induced transcriptomic changes during myoblast differentiation. Discover how the study using is transforming our understanding of FSHD at the molecular level.

📖 Read the full paper here: https://hubs.ly/Q02BlQby0

New Distributorship Announcement! Gene Company is authorized to distribute Elitech Temperature Data Logger in Hong Kong and Macau!

Contact us for more information or demonstration.

ExCellerate™ T Cell Media, Animal Component-Free (CCM035) | Bio-Techne View ExCellerate™ T Cell Media, Animal Component-Free Primary Cell Culture.

Gene Company is here at 2024 CUHK SBS Research Day!

Come say hi👋 at our booth and chat with our product specialists about the latest technology🧬🦠 to explore the spark to advance your research.

WE offer the following fun engaging activities at the booth:
- Polar animal plush toy giveaway 🐧🐻‍❄️🦭
- FREE Lab gloves trial
- FREE reagent kits and consumables samples
- On-going discount promotion on selected brands
- On-site technical discussion💡

[CST 2024 June promotion begins now! 𝗖𝗦𝗧 ✨𝗕𝘂𝘆 2 𝗚𝗲𝘁 3 promotion until 20 June✨]

Buy any three or more qualifying catalog antibodies, of which the lowest priced antibody is 𝗙𝗥𝗘𝗘‼️

CST, the expert in antibodies, kits, and reagents, delivers superior performance and consistency with Hallmarks of Antibody Validation, generating better result in your study with cell signaling pathways. Gene Company offers great deal to make sure you get the most out of your 2024 research budget, and show our support to your hardworking projects in the remaining year!

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The Barkey Plasmatherm is our user-friendly solution for heating and thawing Fresh Frozen Plasma (FFP), erythrocyte concentrate (EC) as well as cryopreserved preparations such as stem cell therapies (HPC). Our medical dry temperature control equipment is the first choice when it comes to efficient thawing with hospital hygiene in mind.

Features:

Dry thawing process - No direct contact with water
Low maintenance - Cleaning by wipe disinfection is sufficient in daily use. The water only needs to be changed once a year.
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Customizable - Four programs that can be easily set by the user, includes time and temperature.

For more information, please contact [email protected] or +85228966283

Link：https://en.barkey.de/en/product/barkey-plasmatherm-cg/6

Find out how Covaris truXTRAC®️ FFPE SMART Solutions, combined with the R230 Focused-ultrasonicator, gently and efficiently provide complete deparaffinization, extraction, purification, and shearing for your hashtag sample prep. Your work will be easier, your results more robust, and your downstream analysis more revealing.

Read More here: https://www2.covaris.com/set-the-nucleic-acids-free...

For more info about Covaris products, please contact local distributor at [email protected]

The Tapestri Genome Editing Solution empowers researchers with a high level of sensitivity, specificity, and reproducibility when analyzing knockout and base editing experiments.

In this App Note, learn more about how by examining zygosity and the simultaneous occurrence of on- and off target edits, researchers can gain invaluable insights into the depth of editing within individual cells.
Get all the details in the App Note here 👉 https://missionbio.com/resources/technical-notes/unprecedented-resolution-of-genome-editing-outcomes-with-single-cell-analysis/?utm_source=linkedin&utm_medium=referral&utm_content=application+note&utm_campaign=2024_Digital+Marketing+General

For enquiries, please contact local distributor at [email protected]

Keep 4 key questions in mind when comparing quality of spatial genomics technologies.

Check out Vizgen MERSCOPE for highest quality in your spatial genomics research. Contact us for more details at [email protected]

What Does High-Quality Spatial Genomics Data Look Like?

In the rapidly evolving field of , distinguishing high-quality data is crucial yet challenging. As researchers work towards standardizing measurements and performance benchmarks, the demand for reliable and usable data is more pressing than ever.

To harness the full potential of these spatial technologies, researchers must focus on specific metrics to ensure data quality. Here are four key questions to help assess and compare the quality of spatial genomics technologies.

📘 For a deeper dive into how you can ensure the highest data quality in your spatial genomics experiments, download our free e-book: https://hubs.ly/Q02x9XTh0

SignalStar multiplex IHC from Cell Signaling Technology is continuously expanding their library of antibodies. Check out the newest antibodies released below:

CD36 (E8B7S) & CO-0089-488 SignalStar™ Oligo-Antibody Pair #95886
CD36 (E8B7S) & CO-0089-594 SignalStar™ Oligo-Antibody Pair #23418
CD36 (E8B7S) & CO-0089-647 SignalStar™ Oligo-Antibody Pair #52907
CD36 (E8B7S) & CO-0089-750 SignalStar™ Oligo-Antibody Pair #70491

IL-2Rα/CD25 (E9W2J) & CO-0074-488 SignalStar™ Oligo-Antibody Pair #34325
IL-2Rα/CD25 (E9W2J) & CO-0074-594 SignalStar™ Oligo-Antibody Pair #45695
IL-2Rα/CD25 (E9W2J) & CO-0074-647 SignalStar™ Oligo-Antibody Pair #58696
IL-2Rα/CD25 (E9W2J) & CO-0074-750 SignalStar™ Oligo-Antibody Pair #71915

CD11b/ITGAM (E4K8C) & CO-0083-488 SignalStar™ Oligo-Antibody Pair #39172
CD11b/ITGAM (E4K8C) & CO-0083-594 SignalStar™ Oligo-Antibody Pair #84898
CD11b/ITGAM (E4K8C) & CO-0083-647 SignalStar™ Oligo-Antibody Pair #27353
CD11b/ITGAM (E4K8C) & CO-0083-750 SignalStar™ Oligo-Antibody Pair #56034

OX40L (D6K7R) & CO-0087-488 SignalStar™ Oligo-Antibody Pair #49516
OX40L (D6K7R) & CO-0087-594 SignalStar™ Oligo-Antibody Pair #58323
OX40L (D6K7R) & CO-0087-647 SignalStar™ Oligo-Antibody Pair #73292
OX40L (D6K7R) & CO-0087-750 SignalStar™ Oligo-Antibody Pair #95054

For more information, please visit https://www.cellsignal.com/browse?tab=product&categories=SignalStar%26%238482%3B%20Multiplex%20IHC%20Kits%20%26%20Reagents

For enquiries, please contact us at [email protected] or +85228966283

This Alzheimer's disease study used LUNA-FL fluorescence cell counter from Logos Biosystems to count isolated nuclei for downstream snRNA sequencing.

Check out LUNA-FL with us at [email protected]

Characterisation of premature cell senescence in Alzheimer’s disease using single nuclear transcriptomics - Acta Neuropathologica Aging is associated with cell senescence and is the major risk factor for AD. We characterized premature cell senescence in postmortem brains from non-diseased controls (NDC) and donors with Alzheimer’s disease (AD) using imaging mass cytometry (IMC) and single nuclear RNA (snRNA) sequencing (> ...

At AACR 2024, Vizgen introduced the groundbreaking MERSCOPE® Ultra Platform & MERFISH 2.0 Chemistry! These advancements are powering a leap in basic and translational research, offering researchers unprecedented depth and breadth in analysis.

On presented poster - Improved Spatially Resolve Single-Cell Transcriptomic Imaging in Archival Tissues with MERSCOPE, the enhanced MERFISH methods (optimized probe design + improved RNA anchoring) leads to:
✓ Improved MERFISH detection in degraded RNA samples.
✓ Increased MERSCOPE sensitivity in both low and high quality FFPE samples, as well as fresh frozen samples.
✓ Well-performed in a range of tissue types.​
✓ Enabled profiling of the cell types in the tumor microenvironment, as well as deeper investigation into the types of immune cells in the tumor sample.

To know more about MERSCOPE, contact us at [email protected]

𝐏𝐫𝐨𝐭𝐞𝐢𝐧 𝐪𝐮𝐚𝐧𝐭𝐢𝐟𝐢𝐜𝐚𝐭𝐢𝐨𝐧 𝐚𝐧𝐝 𝐪𝐮𝐚𝐥𝐢𝐟𝐢𝐜𝐚𝐭𝐢𝐨𝐧

𝐅𝐚𝐬𝐭, 𝐚𝐜𝐜𝐮𝐫𝐚𝐭𝐞 𝐚𝐬𝐬𝐞𝐬𝐬𝐦𝐞𝐧𝐭𝐬 𝐨𝐟 𝐬𝐚𝐦𝐩𝐥𝐞 𝐜𝐨𝐧𝐜𝐞𝐧𝐭𝐫𝐚𝐭𝐢𝐨𝐧 𝐚𝐧𝐝 𝐩𝐮𝐫𝐢𝐭𝐲

Researchers need ways to quickly quantify various biomolecules (e.g., protein and nucleic acid preparations) as a routine part of their workflows. This information helps to make informed decisions before proceeding with downstream experiments. While there are a variety of protein quantification methods to choose from, direct spectrophotometric microvolume UV measurement is a popular choice because it’s simple to perform, requires no reagents or standards, and consumes very little sample.

This application note compendium includes valuable technical documents, application notes, and protocols for measuring proteins using direct and indirect measurements. Additionally, this practical collection contains best practices for sample preparation and measurement to help ensure accurate analysis.

Request your free copy of this compendium today. https://app.info3.thermoscientific.com/e/er?cid=CAD_MCS_UVNN_EM1_04_UVVIS_NanoDropProteinCompendiumGated_GLB_1469881&elqaid=5194&campaignid=2071&s=1474118247&lid=4882&elqTrackId=801087c39c4549838f9cc8bdf1c2a913&elq=864fa5ae8c804225aba9bacf6af25930&elqaid=5194&elqat=1

Contact us for more nanodrop product information - [email protected]

Last call for PacBio SMRT grant. Deadline will be 15 May!. Don't miss the chance to win free sequencing for your cancer research!

Apply link - https://programs.pacb.com/l/1652/2024-03-13/44h4kq?utm_source=Social+Media&utm_medium=LinkedIn&utm_term=textLink&utm_content=LinkedInPost&utm_campaign=2024-04-SMRT-Grant-Cancer-Multiomics

The success of your high-content screening (HCS) and high content analysis (HCA) assays will always be dependent on high-quality, reproducible reagents. CST scientists use HCA in-house to develop and validate our antibodies for use in immunofluorescence applications. This means you can use them with confidence in your screening assays, save valuable time and resources, and increase efficiency in your discovery pipeline.

Any of CST’s antibodies validated for immunofluorescence (IF) may be used in a high content screen. Our catalog of IF-approved antibodies is constantly expanding and includes both post-translational modification (PTM)-specific and total antibodies against targets in many disease-related signaling pathways. Whether your HCS/HCA endpoint requires measuring target expression, subcellular localization or PTM / activation state, CST antibodies enable quantitative endpoint analysis for drug screening and disease modeling studies.

For enquiries, please contact us at [email protected] or +85228966283

EnVision Nexus™ from Revvity showed excellent sensitivity in AlphaLISA™ detection capabilities when compared to previous model EnVision 2105.

Check out the app note - https://www.revvity.com/7d8f2741-bf0b-4c37-a539-020102e73237

Contact us for more info at [email protected]

New study using Vizgen MERSCOPE to reveal key determinant in liver disease.

🌟New Study Reveals Key Determinant in Liver Disease!

🌍Non-alcoholic fatty liver disease (NAFLD) affects a third of the global population, leading to , which significantly impacts disease severity and mortality. A recent study has now identified a crucial factor contributing to this condition.

Researchers from Novartis (Novartis Biomedical Research, Basel) have used and technologies on primary human hepatic stellate cells to pinpoint ZNF469 as a key regulator of collagen expression, crucial for in . This discovery was made through a comprehensive analysis involving transcriptional profiling of 108 human liver biopsies, covering the entire spectrum of .

The study highlights how directly interacts with genes and regulatory elements to control collagen levels and matrix homeostasis, marking it as a critical target for potential therapies.

💡 This breakthrough provides hope for better understanding and treating NAFLD-associated liver fibrosis, potentially saving millions of lives.

📖 Read the pre-print: https://hubs.ly/Q02vhDc-0

The oasig™ OneStep Lyophilised Master Mix simplifies real-time PCR analysis by providing all the necessary components in a single reaction mix. It is versatile and suitable for a variety of assays, including gene expression studies and pathogen detection from RNA. This master mix is compatible with probe-based assays and is specifically designed to perform well with RNA extracted from clinical sample types. It is available with Rox, enhancing its compatibility and performance across different qPCR machines.

Key product features include:
◾ Convenient one-step, closed tube reaction: Simplifies experimental workflow and minimizes the risk of contamination.
◾Broad detection range: Suitable for detecting a wide variety of pathogens, offering flexibility in experimental design.
◾Demonstrated performance with clinical samples: Proven efficacy with RNA extracted from clinical sample types, ensuring reliable results in diagnostic applications.
◾Suitable for all qPCR machines: Compatibility across different platforms ensures versatility and accessibility for researchers using various equipment.
◾Lyophilized – no need for cold chain shipping: The lyophilized form of the master mix eliminates the need for cold chain shipping and storage, simplifying logistics and reducing costs.

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Embrace this opportunity and stock up on your laboratory essentials.

A broad range of Neptune Biotix pipette tips and microcentrifuge tubes are up to 35% off, offering superior quality at a competitive price!

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All promotional products are first come first serve, so order while stock last!

For more information, please visit Gene Company website at:
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Over 350 reviews 👨‍🔬 with average 4.8⭐️out of 5 rank for LUNA-II Automated .

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Contact us to save your time in cell counting and make it reproducible!

LUNA-II™ Automated Cell Counter from Logos Biosystems | SelectScience Read independent reviews on LUNA-II™ Automated Cell Counter from Logos Biosystems on SelectScience

What are the challenges you have been met when developing a safe and effective immune cell therapies?

Click to learn how Bio-Techne's products can help to mitigate risks, boost reproducibility, and enable you to draw the meaningful conclusions you need to drive clinical advances.

Finalize Your Immune Cell Product Characterization! Bio-Techne supports immune cell therapy manufacturing with GMP products and services for isolation and cell culture, genome engineering, and cell characterization.

[Mission Bio] Tumors represent intricate ecological systems in which diverse clonal subpopulations interact and co-evolve within the context of their microenvironmental niches.

Recently published in Science Magazine and presented at , author Alex (Chieh-Yuan) Li dives into how the innovative Clonal Replica Tumors (CRTs) modeling was leveraged to study the clonal evolution of pancreatic ductal adenocarcinoma from primary lesion growth to overt disease dissemination

Read it here:

Publication Highlight: Clonal dominance defines metastatic dissemination in pancreatic cancer | Mission Bio Tumors represent intricate ecological systems in which diverse clonal subpopulations interact and co-evolve within the context of their microenvironmental niches. The process of clonal evolution, spanning from the initial neoplastic lesions to the terminal metastatic disease state, is a continuous p...

Congratulations on Vizgen's growing patent portfolio and advanced technologies are revolutionizing the field of Spatial Transcriptomics!

📢 Vizgen Announces Major Patent Milestone for Spatial Genomics! We're excited to share a monumental step forward in the pursuit of scientific discovery. The US Patent Office has officially granted Vizgen, Inc., U.S. Patent No. 11,959,075, for our technology, paving the way for innovation in the spatial transcriptomics realm.

Patent Highlights:
-Robust multiplex imaging of RNA within its spatial context.
-Protection for our industry-leading MERFISH technology.
-Newly issued patent available for licensing

This news arrives hot on the heels of AACR 2024, where we showcased the upcoming MERSCOPE® Ultra Platform and introduced the new MERFISH 2.0 chemistry—yet another leap in supporting crucial research efforts.

Learn more: https://hubs.ly/Q02t08Jn0

The submission window is now open for cancer multiomics PacBio SMRT Grant!

Are you ready to accelerate cancer research with stunningly complete genomes, epigenomes, and transcriptomes?

Now is your chance to win free sequencing and revolutionize your work with cutting-edge HiFi data.

See here for more details on how to apply: https://programs.pacb.com/l/1652/2024-03-13/44h4kq?utm_source=Social+Media&utm_medium=LinkedIn&utm_term=textLink&utm_content=LinkedInPost&utm_campaign=2024-04-SMRT-Grant-Cancer-Multiomics

2024 PacBio SMRT Grant | Cancer Multiomics The submission window is now open! Are you ready to accelerate your research with stunningly complete genomes, epigenomes, and transcriptomes?Now is your chance to win free sequencing and revolutionize your cancer research with cutting-edge HiFi data. To participate, tell us in 100 words or less abo...

oasigPLUS delivers a unique technology that eliminates reverse transcriptase activity at room temperature, improving multiplexing results and delivering superior performance.

Due to the increased number of primers, multiplex RNA assays are at an increased risk of non-specific artefact formation (e.g. primer dimers).

This is because the Reverse transcriptase (RTase) is active at room temperature during reaction setup when primers are bound in a non-specific fashion. However, RTase is the enzyme required to drive the PCR of RNA targets.

oasigPLUS OneStep Master Mix uses tightly controlled temperature-dependent reverse transcriptase enzyme technology, removing unwanted primer interactions during room-temperature setup. So you get improved multiplexing performance. 📈

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Join the webinar on 18 April (11am) to know more about microbial WGS and metagenome using new PacBio HiFi plex prep kit!

This exciting new kit allows users to sequence small genomes with higher read-quality scores at a reduced cost.

https://programs.pacb.com/l/1652/2024-02-27/44g5ht?utm_source=Social+Media&utm_medium=LinkedIn&utm_term=textLink&utm_content=LinkedInPost&utm_campaign=2024-04-Webinar-Microbial-Prep-Kits

More samples, lower costs, less time: New PacBio HiFi prep kits + Microbial WGS and AMR New, high-throughput library preparation solutions from PacBio, combined with highly accurate long-read sequencing, are enabling researchers to achieve deeper genomic insights more efficiently than ever before. In this webinar, our speakers will present a comprehensive overview of scalable, automate...