LitUp - Literature Updates
"Literature updates", spam scientifico erratico ed arbitrario dei contenuti delle riviste che gli ana Please signal Journals NOT covered! Thank you.
"Literature updates", spam scientifico erratico ed arbitrario dei contenuti, rilevanti per la futura professione di Patologo, delle riviste che gli anatomopatologi NON leggono, semplicemente ignorano. "Literature updates", arbitrary and erratic scientific spamming of the content, relevant for the future practice of Pathology, that current Pathologist do not read, simply ignore. Covered journals an
06/12/2023
Merry Christmas
Pathologists in Venice | ON SITE MEETING PATHOLOGISTS IN VENICE real world cases for an immersive training experience December, 12-13, 2024 SS. Giovanni e Paolo Hospital Venice, Italy CLICK HERE TO FIND OUT THE EVENT PROGRAM Fee Early bird (10% discount)Physicians, Biologist: € 449.00Residents: € 314.00 CLICK HERE TO RE...
21/10/2023
https://pathologistsinvenice.com pre register open now !!!!
Pathologists in Venice | SAVE THE DATE PATHOLOGISTS IN VENICE real world cases for an immersive training experience December, 12-13, 2024 Venice, Italy CLICK HERE TOPRE-REGISTER FOR THE EVENT The Masters Angelo Paolo Dei Tos Department of Pathology, Azienda Ospedale Università Padova, Padova, Italy Liron Pantanowitz Depart...
08/10/2023
https://authors.elsevier.com/a/1htl7grrSW1V
Evolution of Lymphoma Diagnosis in the Era of Personalized Medicine: A Marriage of Pathology and Genomics for Clinical Practice The modern taxonomy of disease builds a framework for precision medicine, by which traditional pathologic criteria are integrated with clinical and ge…
30/08/2023
19/08/2023
https://www.nature.com/articles/d41586-022-03668-7
Should I join Mastodon? A scientists’ guide to Twitter’s rival The open-source platform has added nearly half a million users in little more than a week — but should scientists make the leap? We examine the pros and cons.
18/08/2023
Thousands of scientists are cutting back on Twitter, seeding angst and uncertainty A Nature survey reveals scientists’ reasons for leaving the social-media platform now known as X, and what they are doing to build and maintain a sense of community.
11/07/2023
https://acsjournals.onlinelibrary.wiley.com/doi/full/10.1002/cncy.22741 special summer edition
Digital Examination of LYmph node CYtopathology Using the Sydney system (DELYCYUS). An international, multi‐institutional study The Sydney system for reporting lymph node cytopathology exhibits adequate interobserver concordance. Digital microscopy is an adequate means to assess lymph node cytopathology specimens.
01/07/2023
https://pubmed.ncbi.nlm.nih.gov/35512230/ by Stefano Ceola
Endometrial Polyp in Postmenopausal Women: An Epicenter for the Development of Endometrial Serous Carcinoma - PubMed A close topographic relationship between MUSC and endometrial polyp has been consistently observed in many studies: more than two-thirds of MUSCs involve an endometrial polyp and >50% of MUSCs are confined to an endometrial polyp at the time of staging hysterectomy, indicating that most if not al .....
27/06/2023
https://twitter.com/4oncommunity/status/1673707248927776768?s=48&t=CuzGTOgEjL8hkqyeOGy5Mg
4oncommunity on Twitter “Guests of the 2° episode: Prof. , Professor of Pathological Anatomy and Head of Specialisation School at . Prof. , Full Professor of Pathology & Head of the Tumor Immunology Unit at . Listen the episode here⬇️ https://t.co/iv2fVdF6op”
22/06/2023
https://link.springer.com/article/10.1007/s00428-023-03574-x by Dr Ceola
Quantification of perineural invasion in pancreatic ductal adenocarcinoma: proposal of a severity score system - Virchows Archiv Perineural invasion (PNI) is a common feature in pancreatic ductal adenocarcinoma (PDAC) and correlates with an aggressive tumor behavior already at early stages of disease. PNI is currently considered as a “present vs. absent” feature, and a severity score system has not yet been established. T...
13/06/2023
https://pubmed.ncbi.nlm.nih.gov/36387281/ by stefano ceola
Tissue management in precision medicine: What the pathologist needs to know in the molecular era - PubMed Precision medicine is "an emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle for each person." Among many medical specialists involved in precision medicine, the pathologists play an important and key role in the...
19/05/2023
https://onlinelibrary.wiley.com/doi/10.1111/his.14883 by Valentina canini
Comparison of Clinicopathological Characteristics, Gene Expression Profiles, Mutational Analysis, and Clinical Outcomes of Pure and Mixed Small Cell Carcinoma of the Bladder HistopathologyAccepted Articles Original Article Comparison of Clinicopathological Characteristics, Gene Expression Profiles, Mutational Analysis, and Clinical Outcomes of Pure and Mixed Small Cell Carcinoma of the Bladder Vamsi Parimi, Vamsi Parimi Departments of Pathology, The Johns Hopkins Medi....
12/05/2023
https://link.springer.com/article/10.1007/s00428-023-03509-6 by Valentina Canini
High-multiplex tissue imaging in routine pathology—are we there yet? - Virchows Archiv High-multiplex tissue imaging (HMTI) approaches comprise several novel immunohistological methods that enable in-depth, spatial single-cell analysis. Over recent years, studies in tumor biology, infectious diseases, and autoimmune conditions have demonstrated the information gain accessible when map...
05/05/2023
https://www.nature.com/articles/s41698-023-00368-x by sem Davide Seminati
Homologous recombination deficiency signatures in gastrointestinal and thoracic cancers correlate with platinum therapy duration - npj Precision Oncology There is emerging evidence about the predictive role of homologous recombination deficiency (HRD), but this is less defined in gastrointestinal (GI) and thoracic malignancies. We reviewed whole genome (WGS) and transcriptomic (RNA-Seq) data from advanced GI and thoracic cancers in the Personalized O...
28/04/2023
In the night Spotify and 4oncommunity voice ! Follow our episodes from today !
https://www.pathologica.it/article/view/837 by same Davide Seminati
18/04/2023
https://www.nature.com/articles/s41698-022-00276-6 by Davide Seminati
Pan-cancer analysis of genomic scar patterns caused by homologous repair deficiency (HRD) - npj Precision Oncology Homologous repair deficiency (HRD) is present in many cancer types at variable prevalence and can indicate response to platinum-based chemotherapy and PARP inhibition. We developed a tumor classification system based on the loss of function of genes in the homologous recombination repair (HRR) pathw...
31/03/2023
https://pubmed.ncbi.nlm.nih.gov/36579550/
A novel NGS-based diagnostic algorithm for classifying multifocal lung adenocarcinomas in pN0M0 patients - PubMed The classification of multifocal lung adenocarcinomas (MLAs), including multiple primary lung adenocarcinomas (MPLAs) and intrapulmonary metastases (IPMs), has great clinical significance in staging and treatment determination. However, the application of molecular approaches in pN0M0 MLA diagnosis....
24/03/2023
https://pubmed.ncbi.nlm.nih.gov/36482271/
Artificial intelligence in breast cancer histopathology - PubMed This is a review on the use of artificial intelligence for digital breast pathology. A systematic search on PubMed was conducted, identifying 17,324 research papers related to breast cancer pathology. Following a semimanual screening, 664 papers were retrieved and pursued. The papers are grouped int...
20/03/2023
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839590/
Resistance to BTK inhibition in CLL and non-Hodgkin lymphoma Bruton tyrosine kinase inhibitors (BTKi) have transformed the therapeutic landscape of chronic lymphocytic leukemia (CLL) and Non-Hodgkin lymphoma (NHL). However, primary and acquired resistance to BTKi can be seen due to a variety of mechanisms including ...
17/03/2023
https://pubmed.ncbi.nlm.nih.gov/36726072/ by Elisa Belloni
Characterisation of tumour-immune phenotypes and PD-L1 positivity in squamous bladder cancer - PubMed Computer-based image analysis is an efficient tool to analyse immune topographies in squamous bladder cancer. Hot tumour-immune phenotypes with strong PD-L1 expression might pose a promising subgroup for clinically successful ICI therapy in squamous bladder cancer and warrant further investigation.
14/03/2023
https://ai.googleblog.com/2023/03/learning-from-deep-learning-case-study.html?m=1
Learning from deep learning: a case study of feature discovery and validation in pathology Tuesday, March 14, 2023 Posted by Ellery Wulczyn and Yun Liu, Google Research When a patient is diagnosed with cancer, one of the most important steps is examination of the tumor under a microscope by pathologists to determine the cancer stage and to characterize the tumor. This information is centr...
10/03/2023
https://pubmed.ncbi.nlm.nih.gov/35512215 by Elisa Belloni
PRAME Expression in Endometrioid and Serous Endometrial Carcinoma: A Potential Immunotherapeutic Target and Possible Diagnostic Pitfall - PubMed Preferentially expressed antigen in melanoma (PRAME) is a cancer te**es antigen initially employed as a diagnostic marker for melanoma. Although negative in most normal tissues, its expression has been reported in benign endometrial glands. Additionally, PRAME expression has been identified in a gro...
04/03/2023
Integrative pan-cancer genomic and transcriptomic analyses of refractory metastatic cancer Abstract. Metastatic relapse after treatment is the leading cause of cancer mortality, and known resistance mechanisms are missing for most treatments administered to patients. To bridge this gap, we analyze a pan-cancer cohort (META-PRISM) of 1,031 refractory metastatic tumors profiled via whole-ex...
17/02/2023
https://www.esmoopen.com/article/S2059-7029(23)00010-8/fulltext
Targeting HER3 for cancer treatment: a new horizon for an old target Human epidermal growth factor receptor 3 (HER3) is a member of the human epidermal growth factor receptors family, having as its main ligands neuregulins 1 and 2. Although its poor tyrosine kinase activity entails a weak oncogenic power on its own, HER3 can heterodimerize with HER2 and/or epidermal....
13/02/2023
https://journals.lww.com/jasn/Citation/9900/Kidney_Genetics__Continuing_Discoveries_and_a.84.aspx
Kidney Genetics: Continuing Discoveries and a Roadmap to... : Journal of the American Society of Nephrology An abstract is unavailable.
07/02/2023
Life lessons after a career in intensive care medicine - Intensive Care Medicine From the Inside Published: 08 November 2021 Life lessons after a career in intensive care medicine J. Randall Curtis ORCID: orcid.org/0000-0001-9529-845X1,2 Intensive Care Medicine volume 48, pages 257–258 (2022)Cite this article 167k Accesses 3 Citations 704 Altmetric Metrics details Working on a...
06/02/2023
Overview of the 2022 WHO Classification of Parathyroid Tumors
Lori A Erickson et al. Endocr Pathol. 2022 Mar. By Nicole Dominique Greco https://pubmed.ncbi.nlm.nih.gov/35175514/
Overview of the 2022 WHO Classification of Parathyroid Tumors - PubMed The 2022 WHO classification reflects increases in the knowledge of the underlying pathogenesis of parathyroid disease. In addition to the classic characteristic features of parathyroid neoplasms, subtleties in histologic features which may indicate an underlying genetic abnormality reflect increased...
Esr1 mutations in cfDNA and breast cancer . A new must in precision oncology https://ascopubs.org/doi/pdfdirect/10.1200/JCO.22.00338
19/01/2023
https://pubmed.ncbi.nlm.nih.gov/36009506/ litup coffe break tomorrow at 2023 apunimib.it
CAR T-Based Therapies in Lymphoma: A Review of Current Practice and Perspectives - PubMed While more than half of non-Hodgkin lymphomas (NHL) can be cured with modern frontline chemoimmunotherapy regimens, outcomes of relapsed and/or refractory (r/r) disease in subsequent lines remain poor, particularly if considered ineligible for hematopoietic stem cell transplantation. Hence, r/r NHLs...