Nrs. Destiny Clinic/Pharmacology

The full meaning of PCM?

Feverish treatment

Happy time

A wonderful celebration

𝐌𝐞𝐝𝐢𝐜𝐚𝐥 𝐒𝐏𝐎𝐍𝐃𝐘𝐋𝐎𝐒𝐈𝐒 𝐒𝐭𝐮𝐝𝐢𝐞𝐬 𝐑𝐞𝐯𝐞𝐚𝐥𝐞𝐝 𝐓𝐡𝐚𝐭 𝐋𝐮𝐦𝐛𝐚𝐫 𝐒𝐩𝐨𝐧𝐝𝐲𝐥𝐨𝐬𝐢𝐬, 𝐂𝐞𝐫𝐯𝐢𝐜𝐚𝐥 𝐒𝐩𝐨𝐧𝐝𝐲𝐥𝐨𝐬𝐢𝐬, 𝐒𝐜𝐢𝐚𝐭𝐢𝐜𝐚 𝐚𝐧𝐝 𝐀𝐫𝐭𝐡𝐫𝐢𝐭𝐢𝐬 have no age limits and it tears down the spinal disc of those affected and becomes worse if not treated early?

Ask Dr. Mandela 😷👨🏼‍⚕️

Pharmacology of Topiramate

Topiramate is an antiepileptic medication with a broad range of pharmacological actions. It is used for the treatment of epilepsy and is also prescribed for the prevention of migraine headaches. Here are key aspects of the pharmacology of topiramate:

1. **Mechanism of Action:**
- Topiramate's precise mechanism of action is not fully understood, but it is believed to involve multiple mechanisms.
- It enhances the activity of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, by increasing GABA-A receptor activity.
- It inhibits excitatory neurotransmission by blocking voltage-gated sodium channels.
- It modulates the activity of certain glutamate receptors, particularly AMPA/kainate-type glutamate receptors.

2. **Antiepileptic Effects:**
- Topiramate reduces the abnormal electrical activity in the brain, which is associated with seizures.
- It is effective against both partial-onset seizures and generalized tonic-clonic seizures.

3. **Migraine Prevention:**
- Topiramate is also used for the prevention of migraine headaches.
- The exact mechanism for its efficacy in migraine prevention is not fully understood but may involve its ability to modulate neurotransmitter systems and reduce cortical hyperexcitability.

4. **Pharmacokinetics:**
- Topiramate is well-absorbed after oral administration.
- It has a relatively long half-life, allowing for once or twice-daily dosing.
- The drug is eliminated primarily through the kidneys.

5. **Side Effects:**
- Common side effects include cognitive and psychomotor slowing, paresthesia (tingling sensations), and weight loss.
- Serious side effects can include metabolic acidosis, kidney stones, and glaucoma, which may require careful monitoring.

6. **Interactions:**
- Topiramate may interact with other antiepileptic drugs, affecting their concentrations.
- It can also interact with certain medications, leading to potential side effects or reduced

Greatness Lives Here 🇳🇬

Meet Professor Dora Akunyili: a remarkable Nigerian figure who dedicated her life to public health and good governance.

Professor Dora was born, 14 July 1954, in Makurdi, died, 7 June 2014 in India. She graduated with a B.Pharm in pharmacy and later obtained a Ph.D. in pharmacology.

She served as Director-General of the National Agency for Food and Drug Administration and Control (NAFDAC) from 2001 to 2008. Led a fierce campaign against the proliferation of fake and counterfeit drugs in Nigeria, facing threats and intimidation from powerful interest groups. She successfully reduced the availability of fake drugs by over 80% during her tenure, significantly improving public health.

She was appointed Minister of Information and Communications from 2008 to 2010. She championed freedom of information and fought against corruption in the Nigerian government. She introduced transparency measures and spoke out against vested interests, earning her the nickname "Iron Lady" for her courage and determination.

Professor Dora Akunyili is considered a symbol of hope and a role model for aspiring leaders in Africa. Her story continues to inspire individuals and organizations tackling corruption and promoting public health globally.

I AM NIGERIA 🇳🇬 | NIGERIA 🇳🇬 IS ME.

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Q- Which of the following correctly describes permissive drug interaction?
A- Decrease in response of a drug after repeated administration
B- Effect of drug A and drug B is equal to the sum of their individual effects
C- Effect of drug A and drug B is greater than the sum of their individual effects
D- Presence of drug A is required for full effect of drug B
Answer:

Pharmacology MCQs- 257 Q- Which of the following correctly describes permissive drug interaction? A- Decrease in response of a drug after repeated administration

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Widening Participation Medics Network
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Which of the following is the basic characteristic of a living organism?
(a) Ability to move
(b) Ability to reproduce
(c) Ability to eat
(d) Ability to breath

Which of the following vitamin is produced in the body with the help of sunlight?
(a) Vitamin D
(b) Vitamin E
(c) Vitamin K
(d) None of these

Which one of the following is an example of hereditary disease?
(a) AIDS
(b) Hemophilia
(c) Syphilis
(d) Formalin

The study of Pregnancy women is called??

Anthology
Mythology
Gynecology
Cytology

Ecosystem: A system formed by an ecological community and its environment that functions as a unit.The interconnectedness of organisms (plants, animals, microbes) with each other and their environment.business marketing A set of interconnected products and services.

Appendix is located in what region

Clauses of Low Blood pressure

In Pharmacology 6/12
Means ??

Anatomy of Eye👁️👁️

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