PARN

There is a shortage of trained healthcare workers across the globe

Health-care workers must be trained and retained Globally, health care has a dangerous shortage of workers, and the situation is worsening. On March 8, 2023, a progress report on the International Recruitment of Health Personnel was published by WHO. This report added eight countries to the 2020 list of vulnerable (so-called red-list) countries, i...

Lateral thinking and antimicrobial resistance It might come as a surprise to readers of The Lancet Microbe, but antimicrobial resistance (AMR) is thought to be “largely unknown to the general public”, at least in the USA. An alarming statement given the danger AMR represents. In this month's issue we have a range of items covering various f...

The role of bacterial vaccines in the fight against antimicrobial resistance

The role of bacterial vaccines in the fight against antimicrobial resistance: an analysis of the preclinical and clinical development pipeline Vaccines can be highly effective tools in combating antimicrobial resistance as they reduce infections caused by antibiotic-resistant bacteria and antibiotic consumption associated with disease. This Review looks at vaccine candidates that are in development against pathogens on the 2017 WHO bacteri...

The death of a wonder drug Once a bug becomes impervious to many – or even all – antibiotics, then all of us are in very serious trouble

Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis To our knowledge, this study provides the first comprehensive assessment of the global burden of AMR, as well as an evaluation of the availability of data. AMR is a leading cause of death around the world, with the highest burdens in low-resource settings. Understanding the burden of AMR and the lea...

With dangerous superbugs on the rise, hospital cleanup means life or death When you’re a patient, which room or bed you’re put in largely determines your risk of getting infected.

Neonatal sepsis: the new threat posed by superbugs Over-use of antibiotics has created a deadly, largely hidden health crisis among newborns that is devastating families around the world.

Automating the Generation of Antimicrobial Resistance Surveillance Reports: Proof-of-Concept Study Involving Seven Hospitals in Seven Countries Background: Reporting cumulative antimicrobial susceptibility testing data on a regular basis is crucial to inform antimicrobial resistance (AMR) action plans at local, national, and global levels. However, analyzing data and generating a report are time consuming and often require trained personnel...

Why are Pakistan’s floods so extreme this year? One-third of the country is under water, following an intense heatwave and a long monsoon that has dumped a record amount of rain.

Sequencing effort aims to improve drug-resistant TB diagnosis, treatment The process generates a list of antibiotics to which the infection is susceptible.

I cant agree more, fungi are also becoming resistant to drugs which is making it more difficult to treat fungal infections

Humans are not prepared for a pandemic caused by fungal infections Changes in the environment and climate, as well as fungicide overuse in agriculture, have driven a rise in fungi capable of infecting people and evading the few drugs designed to fight them.

whole genome sequencing is a great tool in determining the antimicrobial resistance in different microorganisms, for details read this article

Investigating resistance in clinical Mycobacterium tuberculosis complex isolates with genomic and phenotypic antimicrobial susceptibility testing: a multicentre observational study - PubMed Bill & Melinda Gates Foundation, German Centre for Infection Research, German Research Foundation, Excellence Cluster Precision Medicine of Inflammation (EXC 2167), and Leibniz ScienceCampus EvoLUNG.

Dr.Egon A Ozer and Dr.Ramon Redondo in collaboration with CDC conducted Pathogen genomics workshop at AKUH explaining bioinformatics software, NGS platforms, sequencing library and alignment, phylogenetic data visualization, enabling better detection of

The landscape of antimicrobial resistance in the neonatal and multi-host pathogen group B Streptococcus: review from a One Health perspective Group B Streptococcus (GBS) stands out as a major agent of pediatric disease in humans, being responsible for 392,000 invasive disease cases and 91,000 deaths in infants each year across the world. Moreover, GBS, also known as Streptococcus agalactiae, is an important agent of infections in animal h...

CDC study highlights community spread of superbugs A US surveillance study found 10% of carbapenem-resistant Enterobacterales infections were community-associated.

Globetrotting microbes in airplane sewage may spread antibiotic resistance Along with harder-to-kill microbes, airplane sewage contains a diverse set of the genes that let bacteria evade antibiotics.

Pandemic resulted in increased antimicrobial resistance, read this interesting finding

CDC: COVID-19 "Perfect Storm" Against Efforts to Reduce Antimicrobial Resistance CDC attributes a 15% increase in deaths from antimicrobial-resistant infections in 2020 to impacts of COVID-19 on health and healthcare.

At last some hope against drug resistant gonorrhoeae, read articles for details

First antibiotic for super-gonorrhea enters human trials as new cases found in England An estimated 82.4 million people were newly infected with gonorrhoea in 2020, with all these cases resistant to at least one antibiotic

Estimating the effect of vaccination on antimicrobial-resistant typhoid fever in 73 countries supported by Gavi: a mathematical modelling study Our results indicate the benefits of prioritising TCV introduction for countries with a high avertable burden of antimicrobial-resistant typhoid fever.

Impact of COVID 19 on core components of healrhcare facilities , and impacts on antimicrobial redistance

COVID-19 & Antibiotic Resistance Antibiotic resistance is still a public health threat during the COVID-19 pandemic. Find the latest data.