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Signs of aging begin on the inside long before they come to the surface resulting in wrinkles and gray hair. Your body is constantly fighting off free radicals, toxins and bacteria that if our body stopped, would lead to disease and rapid aging. But what are things that lead to our body having toxins? Here are everyday habits, that if not managed, can lead to aging:

- Stress
- Bad diet
- Lack of Sleep
- Over exposure of UV rays
- Lack of Exercise

This may seem straight forward, but ensuring you are consistent in focusing on a holistic approach to your health and wellness is key— not just focusing on one.

We will be breaking each of these factors of aging in future posts- make sure to follow to understand how these everyday habits effect your health on a cellular level.

We are a community of next-gen health experts, and we’re changing the way we think about health and longevity.

Join us to receive a peer-reviewed, scientific breakdown on all the facts for living longer, healthier, lives. We also provide you with free tips for your everyday life that can better optimize your longevity, updates on the latest tech and tools for enhancing your routine, and the best podcasts for learning the facts over the fads.

Click the link in our bio and join our community!

We could not be more thankful for the community we have brought together and the lives we are living to the fullest. Wishing you and yours the happiest and healthiest Thanksgiving Day!
Sincerely,
The FOXO team

The holidays are just around the corner, which means your favorite treats of the season are too. We hear a lot about overcoming those holiday indulgences, but what are some practical and more effective ways to protect your metabolism without just saying "no" to everything?

Our scientists’ offer these helpful recommendations:
Practice intermittent fasting: Allow your digestion at least a 12-hour break between dinner and breakfast. This gives your digestive system the break it needs, while priming it for the following day.
Focus on portion control: Eat smaller portions to avoid overindulging. A simple hack? Keep portion size to the size of your palm or smaller.
Choose wisely: Your favorite drink, or your favorite dessert? Indulge in one, not both.

These recommendations aren’t just for the holidays, either. You can implement them into your daily life any time! So, why not start this season a little smarter?

Stress throws your whole body out of whack.

It raises blood pressure, triggers tension headaches, causes irregular breathing, gives you acid reflux, and increases your risk of having a heart attack or stroke. Chronic stress can also increase feelings of depression, trigger panic attacks, and make it difficult to fall or stay asleep. It’s the secret attack on our health that we often ignore.

Luckily, we can combat stress in a variety of ways. Exercise, of course, being one of them. However, we want to talk about ways to bring energy to the body, when we often are expelling energy from the body throughout the day. Different techniques include:

- Restorative yoga & mobility training
- Breathing exercises
- Walking outdoors
- Practicing mindfulness

Believe it or not, incorporating a brisk walk outside to your daily routine is shown to lower stress, blood pressure and heart rate. Spending just 20 minutes in a park — even if you don't exercise there — is enough to improve your well-being, according to the research.

Prioritize mental health and stress management. It’s a key factor in optimizing longevity.

Our team had a blast at the 60 mile bike race!

It was a blast- proud of them & all the athletes!

With so many different “detox” programs, diets, and products out there, it's no surprise you’re conditioned to think of some tortuous diet or weird concoction as the best ways to detox. In truth, your body doesn't need to learn how to detox — your body is already doing that job for you every second of every day, no matter what you eat or drink.

On a daily basis, your liver, kidneys, large intestine, lymphatic system, and sweat glands are working together to reduce the body burden, or buildup, of toxins.

So, why do we still feel a need to detox?

Since we all come into contact with different kinds and varying amounts of toxins every day, that exposure can have a cumulative effect and overburden the body’s effectiveness to detoxify naturally. That sluggishness to detox can lead to other potential problems or symptoms.

Main factors that interfere with your body's natural way of detoxifying are:
❗️Lack of sleep
❗️Poor stress management
❗️Eating inflammatory foods (sugar, starches, wheat, etc)
❗️Lack of hydration

The most effective way to detox your body is by consistently getting the proper nutrition and rest needed. Hydration is key to our everyday life, as it helps our organs to process all the different toxins our body takes in.

So, go take a walk outside, take a nap and drink a lot of water. Your body is resilient!

Keep following FOXO for longevity and health tips that look at the science, not the fads.

With so many different “detox” programs, diets, and products out there, it's no surprise you’re conditioned to think of some tortuous diet or weird concoction as the best ways to detox. In truth, your body doesn't need to learn how to detox — your body is already doing that job for you every second of every day, no matter what you eat or drink.

On a daily basis, your liver, kidneys, large intestine, lymphatic system, and sweat glands are working together to reduce the body burden, or buildup, of toxins.

So, why do we still feel a need to detox?

Since we all come into contact with different kinds and varying amounts of toxins every day, that exposure can have a cumulative effect and overburden the body’s effectiveness to detoxify naturally. That sluggishness to detox can lead to other potential problems or symptoms.

Main factors that interfere with your body's natural way of detoxifying are:
Lack of sleep
Poor stress management
Eating inflammatory foods (sugar, starches, wheat, etc)
Lack of hydration

The most effective way to detox your body is by consistently getting the proper nutrition and rest needed. Hydration is key to our everyday life, as it helps our organs to process all the different toxins our body takes in.

So, go take a walk outside, take a nap and drink a lot of water. Your body is resilient!

Keep following FOXO for longevity and health tips that look at the science, not the fads.

If you want to beat the average and maximize your longevity, what should you do? Here's a list of things to consider:

1. Exercise regularly. Research indicates that moderate exercise practiced regularly can roll back the clock on your DNA.
2. Fill up your plate with vegetables. While there are numerous debates about the best foods for increased lifespan, nearly every expert agrees that eating more vegetables is the way to go.
3. Consider intermittent fasting. Fasting has been shown to significantly extend the life (and improve health) of mice. Studies dating as far back as the 1930s have shown that caloric restriction extends the longevity of mice and other test species.
4. Manage your stress. Stress can have unhealthy effects on your body like increased cortisol levels that cause your body to gain and store fat, negatively impact digestion, and much more.
5. Get enough sleep. This allows your cells time to repair themselves and your body to rejuvenate itself.
6. Cultivate personal relationships. Spending time with loved ones can improve longevity, and deep personal connections have been proven to increase one’s sense of purpose—which studies have shown also increases longevity.

If you can't do it all, do one at a time. Slowly build upon these positive changes so you can live your most optimal life and increase your longevity!

Ever wonder why we're called FOXO? We chose FOXO to represent FOXO3, also known as the longevity gene. The different classes of the FOXO gene orchestrate gene expression that regulates crucial chemical reactions and biological processes like:

· Metabolism
· Cellular Replication
· Cell Cycle Arrest
· DNA Damage Repair
· Detoxification of reactive oxidative species

We are on a mission to make longevity accessible to everyone! Learn about what we are working on and how it can change your life. Link in bio.

Epigenetics is a field of science that looks at how genes are modified by biological and environmental conditions or “markers.”

Essentially, these “markers” tell proteins in a cell to process parts of the DNA in certain ways. This process impacts how the cells behave and carry out various life functions without actually changing the underlying DNA sequence.

Epigenetic modifications are a natural part of human biology, but they may also be prompted by external habits for health—if you are eating to be healthy, how often you are exercising, how well you are managing stress, and how much sleep you are getting.

Epigenetic changes stem from several biological systems, one of which is DNA methylation. DNA methylation occurs when a methyl group—a structural unit of organic compounds—attaches to a gene and changes the gene’s expression by turning it off or on and dimming it up or down.

Taking care of yourself by eating healthy, exercising regularly, managing your stress, getting enough sleep, and interacting with people that have a positive impact on your mental health can eventually cause genetic chemical modifications over time that influence how you age and how long you live.

As the science of epigenetics advances, we are learning more and more that health and aging starts from the inside out, and we have more control over our destiny than we originally thought.

Interested in learning more about your epigenetics and cellular makeup? Sign up to be a beta tester! Link in bio.

There's a lot of advice out there on how to increase focus, but many of these tips bear little relation to what psychologists are discovering about the way the human mind works.

Here are some tips backed by psychologists on how to increase focus:

1. Zone out - Concentration requires a network of brain regions including the frontal cortex, which is responsible for resisting distractions and controlling our natural impulse to do something that seems more fun. Keeping this network functioning requires more energy than the group of brain regions that are active when we are thinking about nothing in particular. Because we spend so much of our time working, we end up running out of steam and that’s when the mind starts to meander. Setting aside a part of your day to rest your mind and let it naturally wander could help you focus more on the tasks that matter.

2. Get in a good laugh - That's right! Psychologists are beginning to acknowledge how doing something fun, or something that makes you laugh, can put you in the right state of mind to stay focused and be more productive. Studies show that humor can replenish our reserves to allow our brain more energy to focus.

3. Take a break and exercise - Body movement has been shown to increase brain function, improve memory and rev up brain activity. Going outside for a walk is the perfect trick to take a mental break and giving your brain what it needs to focus.

At FOXO, we are all about optimizing your health to live a long, healthy life. Interested in getting a kick start? Download our FREE 5 step guide to optimizing your healthspan. Link in Bio.

Reference article: BBC 5 ways science can improve your focus

Is genetic testing worth it? There has been scrutiny around this new technology due to data concerns. But do the pros outweigh the concerns?

If done right and in the interest of the individual (that means YOU), genetic testing has many benefits that can lead to precision medicine and disease prognostication.

It can offer insights into your genetics, including any genetic mutations or predispositions so you can take action and adjust your lifestyle habits to help prevent any future ailments.

Even more good news? More and more companies are safeguarding customer data and ensuring confidentiality to keep data from being used against people. Many consumer-based genetic testing companies anonymize customer data to better protect each individual.

Genetic testing can be a great way to learn more about your biological makeup, cellular health, and any potential issues. And nowadays, it’s safer than ever! If you are interested in learning more about your molecular makeup and actions you can take to help decrease the likelihood of future ailments and disease, join our beta test. https://hubs.ly/H0T-pZ30

Muscles are complex. Not only are they changing and adapting based on how we use them, but they change multiple times in our life. There are muscles we use involuntarily (like the heart muscle) and others we focus on building (like skeletal muscle). So how do we grow and strengthen muscle so we can increase longevity and overall healthspan?

Your muscles are made of many fibers and in order to grow muscles, you need to grow those fibers. This may seem apparent, but you can expand those fibers through exercise. Exercise is one of THE most powerful things you can do to maintain health and see gains throughout your life. Exercise, specifically strength training, doesn't just build muscle mass, but it increases and optimizes our body's use of mitochondria, decreases inflammation, and keeps our nervous system firing. All of these factors help decrease the muscle loss that often occurs as we age.

Interested in learning how to increase your longevity and overall healthspan? Sign up for our FREE 5 step guide to optimizing healthspan. Muscles are complex. Not only are they changing and adapting based on how we use them, but they change multiple times in our life. There are muscles we use involuntarily (like the heart muscle) and others we focus on building (like skeletal muscle). So how do we grow and strengthen muscle so we can increase longevity and overall healthspan?

Your muscles are made of many fibers and in order to grow muscles, you need to grow those fibers. This may seem apparent, but you can expand those fibers through exercise. Exercise is one of THE most powerful things you can do to maintain health and see gains throughout your life. Exercise, specifically strength training, doesn't just build muscle mass, but it increases and optimizes our body's use of mitochondria, decreases inflammation, and keeps our nervous system firing. All of these factors help decrease the muscle loss that often occurs as we age.

Interested in learning how to increase your longevity and overall healthspan? Sign up for our FREE 5 step guide to optimizing healthspan. Link in bio.

True health begins on the inside. That’s why we’ve done our homework to find you 5 new science-based ways to help you live healthier, longer.

Get the free guide to learn how to optimize your healthspan and activate your longevity genes to increase your lifespan. https://hubs.ly/H0T-hjy0

You may have heard the saying “true health begins with the gut.” So…what are some natural ways to improve gut health and reverse aging? Here are a few of the things we’ve found to be helpful based on science:

1. Fasting - Fasting gives your digestive system a break from processing foods and other substances. It gets your body ready to be able to take in and digest foods more optimally.
2. Fermented Foods - Eating fermented foods that are rich in probiotic bacteria—like kimchi, yogurt and tempeh—adds beneficial bacteria and enzymes to your overall intestinal flora, which increases the health of your gut microbiome and digestive system while also enhancing your immune system.
3. Sleep - Getting adequate sleep allows your body and cells to detox and regenerate. This helps your body to heal from the damage done during your waking hours and aids in filtering toxins out of the body.
4. Stress Management - Stress increases the production of cortisol in the body and can cause elevated blood sugar and blood pressure. It suppresses the digestive system, reproductive systems,, and thyroid function. That’s why it’s so important to find ways to effectively manage your stress levels, like meditation and yoga.

These are just a few ways to work on your gut health and improve your overall microbiome for optimal health. Interested in finding out more about your cell health in a way that is personalized to you? Join our beta! Learn more via the link in our bio.

We all know exercise is good for your overall health. Whether you are trying to cut pounds, gain muscles, or maintain your weight—exercise benefits everyone. Many benefits of exercise can be seen or felt over time, such as weight loss or overall strength. But did you know that exercise is also a primary key to longevity?

When you exercise, your cells go through a rejuvenation process that helps repair damaged cells and tissue, creates energy, and detoxes your body. Science has proven that exercise can even reduce your Biological Age—the rate at which your cells are aging—and slow the aging process.

Raise your hand if you’ve ever tried a HIIT Workout (raise hand emoji) and let us know if you love it as much as we do!

Have you ever met someone who looks much older or younger than they actually are? That’s because everyone has two ages: a chronological age based on your birthdate and a biological age based on your genetic factors and lifestyle habits. In short, biological age is how old someone seems based on those factors.

So how do you measure your biological age? By using the science of epigenetics.

The pattern of chemical chains that attach to the DNA in your cells—on-off switches known as epigenetic markers—can reveal how you’re aging and possibly even how much longer you’ll live.

While genetic testing might tell you where you came from, epigenetics promises a glimpse into the future by showing you how fast your cells are actually aging.

Want to learn more about your biological age? Follow FOXO as we prepare to launch our first beta product that will include insights into biological and molecular aging.

Our Chronological Age is based on our date of birth and reflects our yearly trips around the sun. But did you know we all have another—arguably, more important—age? Our Biological Age reflects the condition of our cells and lets us know how fast our body is actually aging.

Unlike our Calendar Age that cannot be changed, our Biological Age is influenced by our environment and lifestyle habits. Diet, exercise, sleep, and stress management all play an important role in determining the rate at which our cells are aging.

Using the science of epigenetics, we can reveal our Biological Age to better understand our cellular health and take actionable steps towards slowing and even reversing the aging process.

If you’re interested in finding out your Biological Age, apply to be part of our beta test. Link in bio.

We all know exercise is good for your overall health. Whether you are trying to cut pounds, gain muscles, or maintain your weight—exercise benefits everyone. Many benefits of exercise can be seen or felt over time, such as weight loss or overall strength. But did you know that exercise is also a primary key to longevity?

Studies have shown that HIIT, Tabata, cellular burst workouts, and endurance training exercises have been the most effective at stimulating cell rejuvenation, boosting mitochondria, removing toxins, improving cognitive function, reducing inflammation, and enhancing sleep. These workouts have been proven to put positive stress on the body, activate your longevity genes, repair your body, and rid your system of dead cells.

Don't sit down on yourself and your health. Every bit of movement matters.

"Research has begun to show an association between poor sleep and a higher risk of accumulating beta-amyloid protein plaque in the brain, one of the hallmarks of the disease."
--Harvard Blog

Scientists are unsure what truly causes Alzheimer's, but they believe a combination of quality sleep and aerobic exercise can be preventative measures for cognitive health as they play a pivotal role in detoxing the body and promoting cell rejuvenation.

What do you think--is quality sleep the answer to preventing Alzheimer’s? Let us know in the comments!

Epigenetics is a field of science that looks at how genes are modified by biological and environmental conditions or “markers.”

Essentially, these “markers” tell proteins in a cell to process parts of the DNA in certain ways. This process impacts how the cells behave and carry out various life functions without actually changing the underlying DNA sequence.

Epigenetic modifications are a natural part of human biology, but they may also be prompted by external habits for health—if you are eating to be healthy, how often you are exercising, how well you are managing stress, and how much sleep you are getting.  

Epigenetic changes stem from several biological systems, one of which is DNA methylation. DNA methylation occurs when a methyl group—a structural unit of organic compounds—attaches to a gene and changes the gene’s expression by turning it off or on and dimming it up or down.

Taking care of yourself by eating healthy, exercising regularly, managing your stress, getting enough sleep, and interacting with people that have a positive impact on your mental health can eventually cause genetic chemical modifications over time that influence how you age and how long you live.

As the science of epigenetics advances, we are learning more and more that health and aging starts from the inside out, and we have more control over our destiny than we originally thought.

Interested in learning more about your epigenetics and cellular makeup? Sign up to be a beta tester! Link in bio.