The Sadayappan Lab

The Sadayappan Lab

The lab is investigating the regulatory, structural, and functional role(s) of the striated muscle protein, myosin binding protein-C, in health and disease.

Establish an integrative, multidisciplinary research, training and education program dedicated to solving the intractable problems associated with cardiovascular disease and health.

Photos from The Sadayappan Lab's post 03/06/2024

Dr. Darshini Desai,
Congratulations on successfully defending your PhD thesis this afternoon!
Your hard work, dedication, and expertise have culminated in this significant achievement, and we are truly impressed by your accomplishments. Your research on cardiac hashtag for hashtag hashtag has undoubtedly contributed valuable insights to the field, and we look forward to seeing how your findings impact future scholarship. As you embark on this new chapter as a doctor, remember that your journey doesn’t end here—it’s just the beginning! We have no doubt that your passion and commitment will continue to drive meaningful advancements. Wishing you continued success, exciting opportunities, and a fulfilling career ahead.

29/05/2024

UC CardiovascularResearch Seminar Series!

29/05/2024

Join us for Recess in the Stadium!

Upcoming Ph.D. Dissertation Defense Announcement for Darshini Desai, MS. 28/05/2024

Darshini Desai, We are thrilled to celebrate your upcoming graduation on June 3, 2024. It feels like just yesterday that you joined our lab, and now you are ready to embark on your postdoctoral journey. Your presence and contributions will be greatly missed in the lab. Wishing you all the best in your future endeavors!

Upcoming Ph.D. Dissertation Defense Announcement for Darshini Desai, MS. Ms. Desai has successfully completed an AHA predoctoral fellowship (20PRE35120272, Jan 2020-Dec 2021), three publications (PMID: 35832193, PMID: 32670090, PM...

24/05/2024

Invitation to Join and Witness in the of of

I am pleased to invite you to join and witness Darshini Desai for the defense of her Doctor of Philosophy (PhD) dissertation in the Molecular, Cellular, and Biochemical Pharmacology program, Department of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, on Monday, June 3, 2024, at 1:00 pm in MSB 5051. Ms. Desai’s dissertation is entitled “Unraveling the Impact of MYBPC3 Variant Using hiPSC-Derived Cardiac Organoids.

Ms. Desai is my fifth PhD student, and she has successfully completed an American Heart Association predoctoral fellowship (20PRE35120272, Jan 2020-Dec 2021), three publications (PMID: 35832193, PMID: 32670090, PMID: 32656747 and bioRxiv pending), and received numerous awards and oral presentations at national meetings. She also spent six months at Bristol-Myers Squibb in 2023 as a research intern to learn more about industrial research operations and projects. Additionally, she has secured a postdoctoral position at a leading academic institution, which will commence soon. I am thrilled to see her grow and succeed as a scientist, and I wish her the best as she publicly defends her thesis work. At this juncture, I thank her mentoring committee and the Molecular, Cellular, and Biochemical Pharmacology Graduate Program for supporting her academic advancement.

18/04/2024

Cardiovascular Health & Disease Grand Rounds - 04/23/2024 - Donald Lloyd-Jones, MD, ScM

05/04/2024

Tiny Science Stories Competition
Date: May 7, 2024 (4 pm)
Location: MadTree (3301 Madison Ave, Cincinnati, OH 45209)
We cordially invite you (open to all) to join us in celebrating our efforts to promote cardiovascular research in Cincinnati.
American Heart Association - Ohio
University of Cincinnati
University of Cincinnati College of Medicine

25/10/2023

This is our new paper that defines the role of slow myosin binding protein-C (Mybpc1) in skeletal muscle development, regulation, and function. We hope to publish this in eventually! Comments are welcome!
https://www.biorxiv.org/content/10.1101/2023.10.23.563591v1

21/10/2023

Special Seminar: 2023 THEODORE AND BESSIE CHRISTOPOULOS AWARD AND ENDOWED LECTURESHIP IN CARDIOLOGY

12/09/2023

Department of Internal Medicine Research Conference

07/06/2023

It's time for the 37th OPS Annual meeting.

18/04/2023
13/04/2023

Charles K. Thodeti, Ph.D., FAHA, FCVS
Cardiovascular Grand Rounds
04/18/2023 at noon

29/03/2023

Please join us in MSB 3051 or virtually Tuesday, April 4, 2023 at 12 noon for Cardiovascular Grand Rounds. Dr. Jiang Chang will be presenting “Exploring Conserved Mechanisms and Emerging Concepts in Heart Failure: from Rho Signaling, Epigenomics to Exosomes”.

15/03/2023

Cardiovascular Grand Rounds - Stephen B. Liggett, MD

02/03/2023

SPECIAL INAUGURAL SEMINAR - ALL ARE INVITED!!

01/03/2023

Dr. Song and team, Congratulations!
https://pubmed.ncbi.nlm.nih.gov/36854776/

30/01/2023

Maulee Sheth, Congratulations on your new role as the of the Student Chapter of the Biophysical Society at University of Cincinnati. Thanks to Leyla Esfandiari, Ph.D., for sponsoring the first-year activities. We look forward to working with you to build the chapter and biophysics at BME - University of Cincinnati.

24/01/2023

Cardiovascular disease is the No. 1 killer of women. This National ®, you can be the beat for a woman you love. for the women in your life on Friday, Feb. 3 and help us raise awareness about women's heart health.

Timeline photos 18/01/2023

- is February 3rd! 💃 Are you as excited as we are!? ❤️ 🙌

Home 17/01/2023

Congratulations to Dr. Hesham Sadek and the team: This is an exciting study, and happy to support and be part of the research study defining and treating the cardiac troponin T gene mutation-mediated dilated cardiomyopathy!

Home Research Square is a preprint platform that makes research communication faster, fairer, and more useful.

10/01/2023

Please join us in MSB 2351 or virtually on Tuesday, January 17, 2023 at 12 noon for Cardiovascular Grand Rounds. Dr. David M. Harris, MD will be presenting “Academic Education: Recruitment”.

06/01/2023

Please join us Tuesday 01/10/2023 at 12pm noon in MSB 2351 or via zoomfor Cardiovascular Grand Rounds. Dr. Wei Huang, M.D., Ph.D. from University of Cincinnati Department of Pathology will be presenting "Epigenetic and 3D-genomic Regulation in Cardiac Regeneration".

20/12/2022

Congratulations to Lisa Green, Ph.D. (Postdoc fellow), and Pooneh Nabavizadeh, MD (Cardiologist, PSTP fellow) for securing the AHA Postdoc Fellowship.
American Heart Association - Ohio
American Heart Association

19/11/2022

Gaury Dhamdhere, MBBS
-Graduate Student Rotation (November 2022 – Jan 2023)
-Molecular Genetics, Biochemistry and Microbiology (MOLGEN) Program

Gaury completed her MBBS in India. She has done Master’s in Biology from University of Delaware. Gaury is in her first year of Ph.D. program in the MOLGEN department at University of Cincinnati. She is currently rotating in the Sadayappan lab to learn about generating cardiac organoids, an in vitro three-dimensional model, using human induced pluripotent stem cells for studying the role of MYBPC3 gene variants in hypertrophic cardiomyopathy.

16/11/2022

REGISTRATION IS OPEN

We would like to invite you to join us for our next Cardiac Muscle Society Reception in San Diego, CA. Information to register is below.

REGISTRATION IS OPEN
Cardiac Muscle Society 63rd Annual Reception
San Diego Wine & Culinary Center
February 19, 2023 (Sunday)
5:00-10 PM
https://www.cardiac-muscle-society.org/event-5023756/RegistrationsList

Abstract and Poster Information » Myology Institute » College of Medicine » University of Florida 11/10/2022

2023 Advances in Skeletal Muscle Biology In Health and Disease Conference

Abstract and Poster Information » Myology Institute » College of Medicine » University of Florida   Abstract Submissions Abstracts are now being accepted! Abstracts to be considered for oral presentation, including our Trainee Data Blitz Session, must be submitted by December 12, 2022. All others, for posters, must be submitted by February 8, 2023. All accepted abstracts will be included in our...

05/10/2022

First International Pediatric Cardio-Oncology Conference in Cincinnati | October 21-22, 2022
https://www.cincyhearteducationseries.org/cardio-onc

26/06/2018

Mohammed Arif, PhD, Congratulations!!!

Videos (show all)

Guest of honor's address by Dr. Chellam Rajamanickam

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