The Tapestry Autism Study

Did you know that the gut-brain connection may play a role in ? Researchers have discovered that there may be a link between gut bacteria (our ) and the brain which could contribute to certain behaviors, such as aggression, emotional meltdowns, and self-injury, in children with ( ).

Based on this fascinating research, a new clinical study for children with autism is underway. Learn more about the trial and follow our progress: https://www.theautismstudy.com/

Today we’re shining a spotlight on the Centre for Clinical Trials in Rare Neurodevelopmental Disorders at Children's Health Queensland for their critical role in supporting the Tapestry Study! We’d like to express our heartfelt appreciation to the entire Queensland Children’s team for their unwavering commitment and dedication to the community and their collaboration on this clinical trial.

Learn more about their work and mission at https://www.childrens.health.qld.gov.au/

The TAPESTRY Study is exploring a potential new approach to treating challenging behaviors that children with often face.

If your child has a diagnosis of autism and struggles with behaviors like aggression, destruction, self-harming, isolation and meltdowns, follow and share this page for progress on our clinical trial of AB-2004, a new microbiome-based treatment and potential alternative to anti-psychotic treatments.

Visit www.theautismstudy.com to learn more and follow the trial’s progress!

Our clinical sites and coordinators play an integral role in the success of our ongoing clinical trial, the Tapestry Study. Today, we recognize CNS Healthcare and thank the entire CNS team for their commitment and dedication to the Tapestry Study and the community! Learn more about their work: https://cnshealthcare.com/

Happy Halloween from Axial! 🎃 Wishing our team and community a safe and fun-filled Halloween with great costumes, sweet treats, and laughter!

Halloween is almost here! Check out Cincinnati Children's Hospital Medical Center’s tips to help kids with autism enjoy the spooky season!

🎃 Increasing predictability decreases anxiety
🍬 Consider sensory processing needs
🎃 Be flexible and get creative! Your celebration doesn't have to include conventional traditions

Learn more: Tips for Helping Kids with Autism Enjoy Halloween >>> https://blog.cincinnatichildrens.org/healthy-living/child-development-and-behavior/tips-for-helping-kids-with-autism-enjoy-halloween/

Tips for Helping Kids with Autism Enjoy Halloween Halloween can be tricky for kids who are young, easily startled and/or neurodivergent. Read 4 tips to help them prepare and enjoy it.

We’re pleased to announce the successful completion of enrollment in our Phase 2b clinical trial of AB-2004! AB-2004 is an oral gut-targeted small molecule therapeutic designed to treat irritability associated with autism. Completing enrollment is an important milestone that brings us closer to our goal of addressing the significant unmet need for a safe and effective therapy to treat irritability in autism that works differently from existing medications.

We would like to sincerely thank the children and adolescents who participated in the trial, their families, and caregivers. We also want to extend our gratitude to the clinicians and their staff who conducted this trial at over 25 clinical sites and played an essential role in ensuring that the potential of AB-2004 could be fully explored. This work would not be possible without all of you.

We look forward to sharing data from this clinical trial in early 2024 and bringing forward this innovative therapy to improve the lives of people with autism and their families!

Read the press release to learn more: https://bit.ly/48m3Cnk

Our gut is full of millions of microbes including bacteria and fungi. In this video, we explain how the gut affects the brain and traits. Watch to learn more: https://vimeo.com/740535991

About the TAPESTRY Study - Autism Clinical Trial The clinical trial is researching an experimental treatment, AB-2004, that is designed to adsorb certain substances produced by bacteria in the gut to reduce their…

If your child with is struggling with challenging behaviors such as meltdowns, isolation and aggression, a new clinical trial could help. Researchers have discovered that there may be a link between gut bacteria (our ) and the brain which could contribute to these behaviors in children with ( ).

Based on this fascinating research, the TAPESTRY Study is now enrolling children ages 5-17 with an autism diagnosis.

Interested in learning more? Find out if your child is eligible: www.theautismstudy.com

Today is ! We join the community today – and everyday – to celebrate the diversity of individuals with ASD and the endless opportunities and differences within the autistic community!

We are proud to sponsor the Mount Sinai Seaver Autism Center's 27th Annual Advances in Conference, joining experts from across the field to discuss the latest research with a focus on precision medicine in profound autism. Learn more: https://bit.ly/3VLQj9L

Our ongoing clinical trial-- the TAPESTRY Study-- is evaluating a potential treatment for managing irritability associated with autism that leverages how the brain and gut are connected. Learn more: www.theautismstudy.com

Today at 10:30am ET, our SVP of Clinical Development Science and Operations, Dr. Gabriel Belfort, will present on targeting the gut to treat challenging behaviors in at the Autism Parenting Magazine Summit! A recording of the presentation will be available for 24 hours on the conference website. Learn more: https://bit.ly/3VInzyI

We are thrilled to sponsor and present at the 2023 Autism Parenting Magazine Summit! This free virtual event starts today and features presentations on topics that matter most to people with and their families including research updates. Learn more and register here: https://bit.ly/3px63BM

As comes to a close, we recognize and celebrate the unique perspectives of people with . Together, we can create a more inclusive world. Visit the CDC's Autism and Developmental Disabilities Monitoring (ADDM) Network's website for the latest autism data and resources for early identification and support services: http://bit.ly/3Z9faon

ADDM Network Community Report on Autism A snapshot of ASD among 4 and 8-year-old children across the U.S.

: affects 1 in 36 children. Learn more from the Autism Science Foundation: https://autismsciencefoundation.org/quick-facts-about-autism/

Quick Facts About Autism Defining Autism Autism Spectrum Disorders (ASD) are a complex set of neurological disorders that severely impair social and communicative functioning. Individuals with ASD can range from having cognitive impairments to […]

Researchers have discovered that there may be a link between gut bacteria (our ) and the brain which could contribute to certain behaviors such as aggression, emotional meltdowns, and self-injury in children with ( ). We discuss the gut-brain connection in – and a new clinical study based on this fascinating research – in the latest issue of Autism Parenting Magazine. Check it out: https://www.autismparentingmagazine.com/treat-irritability-associated-with-autism/

Targeting The Gut To Treat Irritability Associated With Autism Spectrum Disorder (ASD) Have you heard about the gut-brain connection in autism? Researchers have discovered that there may be a link between gut bacteria (the microbiome) and the brain, which could contribute to certain challenging behaviors, such as aggression, emotional meltdowns, and self-injury, in autism.

The Autism Society of America is working to create connections and empower everyone in the community to live fully. This , learn more about their campaign!

Acceptance means that together, we create connections for everyone in the Autism community to have access to the unique services, supports, and information needed. Your support on will help us continue to empower Autistic individuals and their families in our local communities every day. https://bit.ly/3Z9nHaG

Today, our SVP of Clinical Development Science and Operations, Dr. Gabriel Belfort, will present on targeting the gut to treat challenging behaviors in at The Autism Community in Action's Take Action Conference! Learn more: https://lnkd.in/gFSKUBbb

Take Action Conference Series APRIL 1-28, 2023 in partnership with IonCleanse by AMD Spectrum Awakening topics of the week April 1-7 April 8-14 April 15-21 April 22-28 Register Now TACA’s Take Action Conference Series is an entirely new offering for TACA families. This virtual month-long opportunity will include live lectures ...

We’re thrilled to sponsor and present at the The Autism Community in Action's 2023 Take Action Conference Series! This virtual month-long series includes live lectures, panel discussions and more to support and inform the community. Learn more: https://bit.ly/41pI3Ou

Take Action Conference Series APRIL 1-28, 2023 in partnership with IonCleanse by AMD Spectrum Awakening topics of the week April 1-7 April 8-14 April 15-21 April 22-28 Register Now TACA’s Take Action Conference Series is an entirely new offering for TACA families. This virtual month-long opportunity will include live lectures ...

Axial Therapeutics, the team of researchers behind the TAPESTRY Study, is proud to celebrate ! We recognize the diversity of experiences within the autism community and we are dedicated to advancing science to make a meaningful difference in the lives of people with autism and their families!

Exciting update to begin ! The TAPESTRY Study has expanded its age eligibility criteria. Now, children ages 5 to 17 (previously 13 to 17) are eligible to enroll in the clinical trial of AB-2004, a gut targeted, molecular therapeutic. This novel small molecule approach is focused on the gut-brain axis connection and offers a potential alternative to anti-psychotic treatments. Learn more: https://bit.ly/3mdLHfg

As comes to an end, check out the Autism Society of America's “The Art of Autism” highlighting 30 black individuals with autism who are making an important impact!

30 Black Autistic People You May Want to Know About The Art of Autism celebrates black autistic influencers (Black History Month). If you have someone you'd like to add to this post, please comment below.

The TAPESTRY Study Clinical Trial | Home The TAPESTRY Study clinical trial is evaluating an experimental drug, AB-2004, that offers a novel approach for the treatment of irritability associated with Autism Spectrum Disorder (ASD). The trial is being conducted in the United States, Australia and New Zealand.

In this video, Mary Moran Heller shares her son Ryan Heller's story and the positive impact a microbiome-based treatment has had on his quality of life with . Mary discusses the potential role microbiome treatments could play in improving the quality of life for people with autism and helping them gain independence. She says that Ryan now has the opportunity to be “part of the world."

Watch here: https://vimeo.com/792621754

Ryan's Story: A Microbiome Treatment Significantly Improved His Quality of Life as an Adult with Autism In this video, Mary Moran Heller shares the story of her son Ryan and his experience with a microbiome-based treatment to help lessen the severity of the challenging…

Our ongoing clinical trial, the TAPESTRY Autism Study, was recently featured in the New Zealand Hеrаld. The article discusses AB-2004, a potential new treatment that targets the gut microbiome to treat challenging behaviors in Autism Spectrum Disorder. Check out the article to learn more: https://bit.ly/3wbvtEQ

The Axial team participated in a holiday gift drive in support of the Doug Flutie, Jr. Foundation for Autism this holiday season! We are proud to support their mission to help people with autism and their families live life to the fullest. Thank you to The Arc of Greater Haverhill-Newburyport, Inc., for helping us deliver these gifts to families in time for the holidays!

Thank you Autism Parenting Magazine for sharing more information about our ongoing , the Tapestry Study, currently enrolling! Visit our website to learn if your teen is eligible to participate: https://www.theautismstudy.com/?apm

Have you heard about the gut-brain connection in ? Researchers have discovered that there may be a link between gut bacteria (our ) and the brain which could contribute to certain behaviors, such as aggression, emotional meltdowns, and self-injury, in teens with ( ).

Based on this fascinating research, a new clinical study for teens with autism is underway.

Interested in learning more? Take the first step! Find out if your teen is eligible here: https://www.theautismstudy.com/?apm

The Tapestry Autism Study

Dr. Sarkis Mazmanian from the Luis & Nelly Soux, Professor of Microbiology at Caltech, discussed the Gut-Brain Axis and the currently enrolling clinical trial, theautismstudy.com, on the NPR Short Wave podcast:
https://www.npr.org/2022/12/12/1142254360/you-know-that-gut-feeling-you-have?

.com

You Know That Gut Feeling You Have?... : Short Wave TFW when you're so excited you get those butterflies in your stomach - or maybe when you see something icky, you feel ill. On today's show, producer Berly McCoy looks at this relationship between our gut and our brain. Berly talks to host Emily Kwong about how the organs evolved to have a tight conn...