MRCGP Myanmar Class Notes
To help about MRCGP [INTERNATIONAL] and MRCGP (South Asia) Myanmar candidates and Myanmar doctors an
How to prepare MRCGP [INT:] AKT
within 3 months
Reference - One Shot Courses
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Choice of OHA in MRCGP
ááźááşáᏠGP áá˝áą DM ááŻáááşááŤáááşá ááŤááąáááˇáş á
áŹááąá¸áá˝á˛ááźáąáá˛áˇáĄá፠ááąá¸áá˝ááşááąá¸áá˝áąáááş á Guideline áĄáááŻááşá¸ ááąáŹááşáááşáĄáąáŹááşááŻáááŻááşáááŻáˇáááşááᯠMRCGP Exam áážáŹ Assess ááŻááşááŤáááşá
OHGP 5th Edition Page 320, 321 áᏠáĄáááŻááşáááąáááŤáááşá
- DM Control ááᯠHbA1c áááşááąáŹááşáá˛áˇ ááźááşááá˛á
- Mono therapy, Dual therapy, Triple therapy áá˝áąáážáŹ áááşááąá¸ááᯠáŚá¸á
áŹá¸ááąá¸ááźáŽá¸ áĄáááşááąáŤááşá¸áážáŹáá˛
- Indication for Initiation of Insulin Therapy
- Side Effects of OHAs
áááŻááźáŽá¸ ááąá¸áá˝ááşá¸áááşááąáŹááşáááşááŤáááşá
áĄáá˝ááşáĄááąáá˛áˇ
Hypoglycemia SE OHAs
đľ Sulphonylureas e.g Gliclazide
đľ Dipeptidylpeptidase-4 inhibitors (DPP4i) e.g Sitagliptip
đľ GLP-1 mimetics e.g exenatide, liraglutide, lixisenatide
đľ Rapid acting insulin secretagogues. e.g repaglinide, nateglinide
Hypoglycemia SE áá
áąáá˛áˇ ááąá¸áááťááŻá¸ááťááŻá¸ááŤááąáááş HbA1c ááᯠáĄááźááˇáşááŹá¸ááźáŽá¸ control áááŤáááşá < 53 ááŤá ááąá¸áááŻá¸ááŹá > 58
đŻ Target HbA1c
Metformin only < 48
Dual therapy < 53
Triple therapy < 53
Weight Increase SE OHAs
âŹď¸ Sulphonylureas e.g Gliclazide
âŹď¸ Pioglitazone
đĽ Pioglitazone also increase risk of CA bladder, bone fracture, fluid retention and heart failure.
Sodium glucose cotransporter 2 inhibitor (SGLT2i) Gliflozins e.g Canagliflozin, Dapagliflozin, Empagliflozin.
âŹď¸ Weight.
ááŤáˇááźáąáŹááˇáş BMI ááťáŹá¸áá˛áˇáá°áᏠHbA1c áááşááąáááş control áááąáŹááşá¸áá°á¸ áááŻáááş SGLT2i áá˝áąááᯠáŚá¸á
áŹá¸ááąá¸áá˝áąá¸áááŤáááşá
ááŽááąááŹáážáŹ GLP-1 mimetics e.g exenatide, liraglutide, lixisenatide áá˝áąááááşá¸ Weight ááťá
áąáááş BMI > 35 áááŻáááşááąá¸áááş áááŻááąáááˇáş Page 321 ááᯠááąááťáŹááźááˇáşáááş Triple Therapy Fail ááźáŽá¸ Insulin áᏠáá°ááŹááŻááşáááşá¸áá˝ááşáá˛áˇ ááááˇáşááąáŹáşááž ááŻáśá¸ááááş áááŻáᏠáááááŤáááşá áááşá¸ááŻáśá¸áááŻáˇ ááááŤá ááŤáˇááźáąáŹááˇáş áŚá¸á
áŹá¸ááąá¸á SGLT2i ááŤá
ááźááşáᏠGP áá˝áą DM ááŻáááşááŤáááşá International Level ááŻáá˛áˇáĄááŤáážáŹ ááááşááᯠááŻááąááťáĄáááŻááşá¸ Metformin + Gliclazide áááŤáááś Sitagliptip ááąá¸ááźáŽá¸ ááŻááąááŻáśáá˛áˇ áááŻáśááąáŹááşááąáŹáˇááŤáá°á¸á International Level áá˛áˇ ááťáąáŹáşááŽá
á˝áŹ upgrade ááŻááşáááŻáˇ áááŻááŹááŤáááşá
DM first line Management á Lifestyle Modification, healthy eating and exercise ááźá
áşááŤáááşá
DM first line Drug á Metformin ááźá
áşááŤáááşá
Control áááąáááş á á á á፠HbA1c ááąáŹááşá
á
áşáááŤáááşá
Latest Guidelines áááŻáááş OHGP 5th Edition á ááąáŹááşááťáááşááŤáááşá Latest NICE Guidelines áááŻáᏠáĄáááşáá°áááŤáááşá
MRCGP Exam Focus ááŤá ááąáŹááąáŹáááş á
áŹááááşááŤá áááşáá˛áˇááąááŹáá˝áąáážáŹáᲠáááşááąá¸ááźááŤá
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