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HOW HEPATITIS IS DIAGNOSED
Depending on the cause and how advanced the disease is, hepatitis typically is diagnosed with some combination of blood work, imaging tests, and liver biopsy. If viral hepatitis is suspected, blood tests are run to detect the presence of a specific hepatitis virus or for antibodies produced by the immune system to fight that virus. Blood tests to look for signs of liver damage may also be used to diagnose viral hepatitis, as well as the non-viral types. More extensive testing may be used to help fully diagnose and assess hepatitis of all types.

LABS AND TESTS
Symptoms that might prompt a doctor to suspect a patient has hepatitis include flu-like or gastrointestinal symptoms, along with jaundice (yellowing of the skin or whites of the eyes, dark urine, or pale stools). These symptoms, plus a medical history and physical exam, are likely to result in the ordering of blood tests.

LIVER FUNCTION TESTS
The blood can provide a great deal of information about how well the liver is working. A liver function test, or liver panel, is used to look for markers of liver disease caused by hepatitis, such as elevated bilirubin (a by-product of blood that's responsible for jaundice) and certain liver enzymes that help with essential functions.

Normally, the liver keeps tight control of these enzymes. But when it's damaged, enzymes can escape into the blood where they can be detected in a small sample drawn by your healthcare practitioner.

The four most common enzymes tested for when liver damage is suspected are:

Alanine aminotransaminase (ALT)
Aspartate aminotransferase (AST)
Gamma-glutamyl transaminase (GGT)
Total Bilirubin

In general, testing for elevated liver enzymes is a solid approach to diagnosing viral hepatitis, but there is one drawback: Although the results can determine if there is liver inflammation, or possibly damage, they can't reveal the cause—in other words, which hepatitis virus is behind the infection.

ANTIBODY TESTS
The immune system makes two types of antibodies specific to individual viruses: As soon as the body identifies one, it produces IgM antibodies to fight that specific virus. Toward the end of infection, the body produces IgG antibodies that also are specific to the virus but function to provide future immunity.

Tests exist for both IgM and IgG antibodies specific to three hepatitis viruses: hepatitis A (HAV), hepatitis B (HBV), and hepatitis C (HCV).

DIRECT VIRAL MASURES (VIRAL LOAD TESTS)
In addition to detecting antibodies for HBV and HCV, tests called polymerase chain reaction, or PCR, tests can be used to directly measure the amount of virus in the blood.

IMAGING
Although imaging tests cannot detect a viral infection of the liver, certain ones can reveal inflammation, changes in size, and tumors that can be consequences of chronic infection or liver disease caused by hepatitis of any type.

Abdominal ultrasound: This test can evaluate abnormalities in the liver and abdomen, and may also detect the fluid build-up in the abdomen, which can occur with liver failure.
Computerized axial tomography (CT): An abdominal CT scan can detect changes in the size and density of the liver and may visualize masses or signs of early cancer (a potential complication of hepatitis).

Magnetic resonance imaging (MRI): An MRI can pick up on abnormalities that suggest liver dysfunction or cancer.
Biopsy

A liver biopsy is a section of tissue taken from the organ and evaluated under a microscope to look for identifying features disease.

The most common type of liver biopsy is called a percutaneous biopsy, which involves inserting a hollow needle through the abdomen into the liver through which a sample of tissue can be extracted.

This is an outpatient procedure, which means it doesn't require a hospital stay. Usually, only local anesthesia is necessary (to numb the area into which the needle will be inserted). However, a sedative can be used if needed.

N/B: Because the symptoms of hepatitis can be mild or mimic other diseases—if there are any symptoms at all—it can be tricky to diagnose. If you have any symptoms that you think might point to a liver problem—especially jaundice—see your doctor. A simple blood test may be all that's necessary to determine if you have hepatitis and if you should be treated.

SYMPTOMS OF HEPATITIS
Common symptoms of hepatitis
If you have infectious forms of hepatitis that are chronic, like hepatitis B and C, you may not have symptoms in the beginning. Symptoms may not occur until the damage affects liver function.

Signs and symptoms of acute hepatitis appear quickly. They include:

*fatigue
*flu-like symptoms
*dark urine
*pale stool
*abdominal pain
*loss of appetite
*unexplained weight loss
*yellow skin and eyes, which may be signs of jaundice

N/B: Chronic hepatitis develops slowly, so these signs and symptoms may be too subtle to notice.

WHAT IS HEPATITIS?
Hepatitis refers to an inflammatory condition of the liver. It’s commonly caused by a viral infection, but there are other possible causes of hepatitis. These include autoimmune hepatitis and hepatitis that occurs as a secondary result of medications, drugs, toxins, and alcohol. Autoimmune hepatitis is a disease that occurs when your body makes antibodies against your liver tissue.

Your liver is located in the right upper area of your abdomen. It performs many critical functions that affect metabolism throughout your body, including:

-bile production, which is essential to digestion
-filtering of toxins from your body
-excretion of bilirubin (a product of broken-down red blood cells),
cholesterol, hormones, and drugs
-breakdown of carbohydrates, fats, and proteins
-activation of enzymes, which are specialized proteins essential to
body functions
-storage of glycogen (a form of sugar), minerals, and vitamins (A, D,
E, and K)
-synthesis of blood proteins, such as albumin
-synthesis of clotting factors

Treatment options vary depending on which type of hepatitis you have. You can prevent some forms of hepatitis through immunizations and lifestyle precautions.

THE TYPES OF VIRAL HEPATITIS
Viral infections of the liver that are classified as hepatitis include hepatitis A, B, C, D, and E. A different virus is responsible for each type of virally transmitted hepatitis.

Hepatitis A is always an acute, short-term disease, while hepatitis B, C, and D are most likely to become ongoing and chronic. Hepatitis E is usually acute but can be particularly dangerous in pregnant women.

Hepatitis A
Hepatitis A is caused by an infection with the hepatitis A virus (HAV). This type of hepatitis is most commonly transmitted by consuming food or water contaminated by f***s from a person infected with hepatitis A.

Hepatitis B
Hepatitis B is transmitted through contact with infectious body fluids, such as blood, vaginal secretions, or semen, containing the hepatitis B virus (HBV). Injection drug use, having s*x with an infected partner, or sharing razors with an infected person increase your risk of getting hepatitis B.

Hepatitis C
Hepatitis C comes from the hepatitis C virus (HCV). Hepatitis C is transmitted through direct contact with infected body fluids, typically through injection drug use and s*xual contact. HCV is among the most common bloodborne viral infections in the United States.

Hepatitis D
Also called delta hepatitis, hepatitis D is a serious liver disease caused by the hepatitis D virus (HDV). HDV is contracted through direct contact with infected blood. Hepatitis D is a rare form of hepatitis that only occurs in conjunction with hepatitis B infection. The hepatitis D virus can’t multiply without the presence of hepatitis B.

Hepatitis E
Hepatitis E is a waterborne disease caused by the hepatitis E virus (HEV). Hepatitis E is mainly found in areas with poor sanitation and typically results from ingesting f***l matter that contaminates the water supply.