COHA This Is One Health

One Health in the news! The amazing work by the
The Dog Aging Project was recently highlighted by
People! https://people.com/pets/dog-aging-project-study/?utm_source=twitter.com&utm_medium=social&utm_campaign=social-share-article

New Study Exploring Canine Aging Hopes to Help Dogs and Their Owners Live Longer The Dog Aging Project is researching canines over the age of 20, or "supercentenarian" dogs, to discover what gives these pets more longevity

Check out Dr. Nicola Mason, Professor of Medicine at the University of Pennsylvania School of Veterinary Medicine, describing the canine comparative oncology trials, part of the Cancer Moonshot Initiative.

https://www.youtube.com/watch?v=bIWaMKZ9pl4

Unleashing Comparative Oncology Dr. Nicola Mason of the University of Pennsylvania School of Veterinary Medicine describes the progress her research team has made in advancing immunotherapy...

Residency-trained veterinarians: Check out this fellowship program to fund your research training with top veterinary scientists.
https://www.ctsaonehealthalliance.org/coha-translational-research-fellowship-opportunity-residency-trained-veterinarians

COHA Translational Research Fellowship Opportunity for Residency-Trained Veterinarians | COHA The CTSA One Health Alliance (COHA) is supporting 2-year research fellowships to engage veterinary clinical specialists in inter-disciplinary and comparative research teams.

New collaborative study led by researchers at University of Minnesota investigates the genomics of vascular tumors in dogs and people, which could lead to targeted treatments. University of Minnesota College of Veterinary Medicine NC State College of Veterinary Medicine & Veterinary Hospital Broad Institute of MIT and Harvard

https://cancer.umn.edu/news/university-minnesota-researcher-published-molecular-cancer-research

University of Minnesota researcher published in Molecular Cancer Research | Masonic Cancer Center MINNEAPOLIS, MN - March 1, 2021 - Jong Hyuk Kim, DVM, PhD, Assistant Professor of Oncology and Comparative Medicine in Veterinary Clinical Sciences and Masonic Cancer Center member, published new research around the causes of canine hemangiosarcoma and human angiosarcoma,

New paper detailing best practices for institutional review of veterinary clinical studies. https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-021-02790-4?utm_source=twitter&utm_medium=social&utm_content=organic&utm_campaign=twitter_2021_bmcseries

A CTSA One Health Alliance guidance on institutional review of veterinary clinical studies Harmonized institutional processes and reviewer training are vital to maintain integrity and ethical rigor of the veterinary clinical research pipeline and are a prerequisite to future work that might establish centralized or single-site ethical and regulatory review to ease initiation of multi-cent...

We're launching an exciting new campaign to share and promote stories and need to hear from you (yes, you!). Tell us about your work, and how the One Health approach can move your field forward. https://enrichly.co/one-health-learning-network/

One Health Learning Network - EnRICHLY| Beyond Knowledge STORIES WANTED: If you have a personal One Health story, or working in One Health, we need to hear from you. Let’s create more collaboration, learning and action in One Health. Stories with propel the movement and help us build the first ever One Health Learning Network.

Despite decades of promise, success using mesenchymal stromal cell ( ) therapy to treat injury and disease remains elusive. Researchers at the Baker Institute at Cornell University College of Veterinary Medicine gain important insights into this challenge using tissues.
https://pubmed.ncbi.nlm.nih.gov/33276815/

Single-cell RNA sequencing of equine mesenchymal stromal cells from primary donor-matched tissue sources reveals functional heterogeneity in immune modulation and cell motility - PubMed Ultimately, these findings will enhance our understanding of MSC heterogeneity and will lead to improvements in the therapeutic potential of MSCs, accelerating the transition from bench to bedside.

"The horse is a representative model of naturally occurring human due to the similarities between human and equine articular and subchondral bone thickness." The Schnabel Lab NC State College of Veterinary Medicine & Veterinary Hospital UNC Thurston Arthritis Research Center North Carolina Translational and Clinical Sciences Institute
https://www.sciencedirect.com/science/article/pii/S1063458420311729?dgcid=coauthor

The combination of mitogenic stimulation and DNA damage induces chondrocyte senescence Cellular senescence is a phenotypic state characterized by stable cell-cycle arrest, enhanced lysosomal activity, and the secretion of inflammatory mo…

"Dogs are similar to us in important ways, like how they act during adolescence and old age, and what happens in their DNA as they get older." The Dog Aging Project https://www.nytimes.com/2020/11/09/science/dogs-aging-behavior.html

Old Dogs, New Research and the Secrets of Aging The ways that dogs grow and age may provide potentially useful similarities with people.

Biobanking is the backbone of precision medicine. Collaborators from Cornell College of Veterinary Medicine and Weill Cornell are investigating whether people and dogs with lymphoma experience similar metabolic changes.
https://www.vet.cornell.edu/news/20200512/banking-new-understanding-canine-and-human-lymphomas

Banking on a new understanding of canine and human lymphomas Chelsey Pickthorn, a cancer survivor, plans on donating her blood to the Cornell Biobank. Her dogs, Hudson (pictured here) and Noma are already biobank donors. This photo: Jocelyn Simone. All other photos by Rachel Philipson unless otherwise noted. It’s been one year since hair artist and salon ow...

This page will be a place to highlight the exciting interdisciplinary work that COHA members are engaged in that advance human, animal, and environmental health.

COHA This Is One Health updated their information in their About section.

COHA (Clinical and Translational Science Award One Health Alliance) consists of veterinary schools partnered with medical colleagues to advance our understanding of diseases shared by humans and animals and find solutions & treatments.