Bulldog Bio, Inc.

This month's Barker introduces the TiYO Autofluorescence Quenching System in more detail. Also we have a sale on our PCR master mixes that you won't want to miss!
https://conta.cc/3zlHIUf

Autofluorescence a problem for your lab? New Autofluorescence Quenching Instrument   Call Us Today! 603-570-4248 Request A Quote Eliminate background autofluorescence via low impact photobleaching We're always looking for new lab tools to ma

New fully automated nucleic acid purification system from CleanNA. https://conta.cc/4aOB1rj

Need an easier way to purify DNA? New fully automated nucleic acid extractions system   Call Us Today! 603-570-4248 Request A Quote Purify nucleic acids for less Our long time partner CleanNA is recognized as a leader in carboxylated

Check out our March Once Bitten eNewsletter here: https://conta.cc/3TCgNLJ
You'll find huge savings on multiple products related to PCR.

Save Big with PCR Once Bitten -- March 2024   Call Us Today! 603-570-4248 Request A Quote Once Bitten | March 2024 PCR products at amazing prices We have too much inventory of existing and new products for labs that re

We've just sent out our January Once Bitten eNewsletter that introduces Nepa Gene's new TiYO Autofluorescence Quenching System. This system removes background fluorescence from cells and tissues prior to immunofluorescence imaging making signals much easier to analyze. Read the eNewsletter from the link below.
https://conta.cc/49hVTqf

Tools for Cell Analysis Once Bitten -- January 2024   Call Us Today! 603-570-4248 Request A Quote Once Bitten | January 2024 Something old and something new for cell researchers Bulldog Bio has invested in cell biology produ

We've just launched the newest gel documentation system from Nippon Genetics. See the novel advantages of the FastGene FAS-X featuring its proprietary illumination design.

Does your lab image gels? Newest Gel Documentation System from Nippon Genetics   Call Us Today! 603-570-4248 Request A Quote Let Blue/Green LEDs light your way for better gel imaging For the past 10 years Nippon Genetics has b

https://conta.cc/3YPuxUq

Tools for DNA Once Bitten -- August 2023   Call Us Today! 603-570-4248 Request A Quote Once Bitten | August 2023 We like DNA... Bulldog Bio cut its teeth on all things PCR. Before Mike and David started the busines

https://conta.cc/3Dml1xO

Electro-kinetic Transfection of Stem Cells Once Bitten -- July 2023   Call Us Today! 603-570-4248 Request A Quote Once Bitten | July 2023 Multi-phase electroporation levels-up transfection, transformation, and gene editing Nepa Gene, our long-

https://conta.cc/410Wzwv

Western Blot Tools Once Bitten -- April 2023   Call Us Today! 603-570-4248 Request A Quote Once Bitten | April 2023 Recently Expanded Product Line -- Western Blot Reagents! Bulldog Bio has a complete range of tools, rea

We are looking to hire a part-time Office Support Representative at our Webster, NY location. https://www.ziprecruiter.com/k/t/AAJOaJWC2EVEwE9rS0MH-LafZ6tmco2JZwjJqfdWvRmiDvRwWr3MHd279seVuh120fCDbebHSku97cvLLC5bxUPJajBN3msXSyvMX-Pi5BX7IKRGid4Xy-NkRzLCVRNY7c9PxT7_yzdSvSz_hIl04O6mS-rUtMFsaQ9PfVmXTDvi0jXxoAFQyUQBhrfq55QcH20Y-qvXiSWKCekBG_F4-k6QHn358TzFh094e_9aQVR3Kq7Ygsc5kuMC9FAb09Phmi2gIsTAUibRY-q8z54H3zdOExtjIs4LZD_B9tmAnQb9UITlq0seyVEnu1onmPqzzruh_b0rUG1Jc16YmAkLraajo6__Sf2m6_d5oBnRJfaAMetzGNCtpFs0MuCqoDocaO4

Office Support Representative - Webster Office Job in Webster, NY at BULLDOG BIO INC $21-$25/hour BULLDOG BIO INC Office Support Representative - Webster Office in Webster, New York. Easy 1-Click apply today!

https://conta.cc/3A0hZxe

Inflation-proof PCR Enzymes Once Bitten -- August 2022 Call Us Today! 603-570-4248 Request A Quote Once Bitten | August 2022 Quality PCR enzymes at affordable prices Bulldog Bio has invested in developing our own brand of thermo

Learn about our expanded range of tools and reagents for running protein gels. We now offer precast PAGE gels! https://conta.cc/3yxxtd4

Do you run protein gels? Complete PAGE System and Precast Gels from Nippon Genetics Call Us Today! 603-570-4248 Request A Quote New protein analysis tools from Japan Our longtime partner, Nippon Genetics Europe, has been sell

Bambanker® HRM: A new solution for the cryopreservation of PBMCs, Lymphocytes, ES cells, iPS cells and more

Are you ready to experience improvement in cell recovery and viability of your PBMCs, Lymphocytes, ES cells and iPS cells? This xeno-free, serum-free cell freezing media reduces the risk of spontaneous cell differentiation, improving storage and survivability of PBMCs, Lymphocytes, ES cells and iPS cells while greatly simplifying the protocol. Additionally, this ready-to-use freezing media enables long term storage at -80°C (or liquid nitrogen if you prefer) with absolutely no programmed or sequential freezing required. Just add and freeze! Bambanker HRM allows any lab to transport your frozen cells on dry ice without fear of recovery issues.

Check out some recent publications referencing Bambanker® HRM here: https://scholar.google.com/scholar?hl=en&as_sdt=0%2C33&q=%22bambanker+HRM%22&btnG=

And see what researchers have to say about Bambanker® HRM: https://www.bulldog-bio.com/product/bambanker-hrm-cell-freezing-media/ #:~:text=Additional%20Information

Want to try? Ask for about our trial pricing progam here: https://www.bulldog-bio.com/product/bambanker-hrm-cell-freezing-media/

Please check out our recent Once Bitten for the month of April. Lots of savings on PCR products. https://conta.cc/3vC1rto

Low Cost PCR Products Once Bitten -- April 2022 Call Us Today! 603-570-4248 Request A Quote Once Bitten | April 2022 PCR machines and PCR reagents for every lab Bulldog Bio has been selling the same brand of thermal cycler

Our newest promotion bundles Nippon Genetics' FastGene Gel Documentation Systems with a MUPID One Electrophoresis System. FastGene Gel Imager's provide ultra-resolution and super-sensitivity courtesy of their proprietary blue/green illumination technology. The MUPID is an all-in-one slab gel system (power supply integrated).
Read more about these deals here: https://conta.cc/3BZCbAc

Versatile Microvolume Spectrophotometers for fast and easy quantification.

The FastGene® Spectrophotometers are compact stand-alone devices with simple and intuitive touchscreen interfaces. The spectrophotometers include both a direct-micro-volume and a cuvette measuring option.

The FastGene® NanoSpec is offered as an all-round UV-VIS spectrophotometer measuring the widest absorption spectrum (190 nm–850 nm) in seconds by using an array type spectrophotometer technology with Xenon lamp and a super-sensitive CMOS sensor (2048 pixels).

The FastGene® NanoView is an ultra-compact, three wavelength spectrophotometer utilizing long-lived LEDs as a light source — which are capable of quickly measuring a sample’s absorbance at 260 nm, 280 nm, and 600 nm wavelengths.

See the details and request a demo here: https://www.bulldog-bio.com/our-products/protein-reagents/spectrophotometers/

Extract up to 96 samples simultaneously & economically. FDA registered and ideal for COVID-19 testing labs.

The GenePure PRO 96 Nucleic Acid Purification System (NPA-96), listed with the FDA as a registered instrument for nucleic acid extraction and purification, along with the very popular MagaBio Plus Virus DNA/RNA Purification Kit III (pre-packed 96-well plate), has been adopted by several testing labs in North America as it uses a well-established extraction technique commonly used by more expensive automated extraction instruments. The GenePure PRO 96 and its MagaBio kits are easily inserted into this existing workflow with no major changes to protocol or documentation.

See FDA Registered Establishment Number 3016635427: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRL/rl.cfm?lid=711046&lpcd=JJH

Request a Quote or Demo here: https://www.bulldog-bio.com/product/genepure-pro-96-automated-nucleic-acid-purification-system/

Important points to consider when choosing a nucleic acid gel imaging system.
Read about how Nippon Genetic's line of FastGene Gel Imagers might fit your lab's needs. This recent Biocompare article highlights key issues when considering a purchase of a system, such as illumination options, camera optics, and the benefits of safe nucleic acid stains.
https://www.biocompare.com/Editorial-Articles/577406-Improving-Nucleic-Acid-Gel-Imaging/
And see our full range of Gel Imagers here: https://www.bulldog-bio.com/our-products/gel-imaging/

Improving Nucleic Acid Gel Imaging Innovations in dyes and imaging are having an impact on systems.

Cleave N-linked Glycans with Endo S PRIME-LY
See the advantages of our newest addition to our growing line of glycoprotein reagents - endo-β-N-acetylglucosaminidase.
• Cleaves N-linked glycans from ONLY the heavy chain of native IgG molecules
• N-terminal histidine tag for easy removal
• Efficiently cleaves bound IgG from IgG Fc receptors without producing additional damage to native cells
• Ultra-stable lyophilized format

Click here to request a Quote: https://www.bulldog-bio.com/product/endo-s-prime-ly/

Our contract has recently been renewed to continue selling ChromoTek products here in the USA. See today's Once Bitten for some special deals on their nanobody-based affinity reagents. https://conta.cc/3AhCUe5

The Power of Nanobodies Once Bitten -- September 2021 Call Us Today! 603-570-4248 Request A Quote Once Bitten | September 2021 We've extended our longtime partnership with ChromoTek Dr. Klaus Herick, VP Sales and Marketing f

This month's Once Bitten newsletter offers free samples and big savings on some of our favorite new reagents used in cell research. https://conta.cc/3kOoXiW

Tools for your cells Once Bitten -- July 2021 Call Us Today! 603-570-4248 Request A Quote Once Bitten | July 2021 Affordable low oxygen experiments The nBIONIX Hypoxic Cell Culture Kit is a great option for labs wanting t

Achieve More Complete Glycan Release with PNGase F PRIME Glycosidase

• PNGase F PRIME Glycosidase catalyzes the cleavage of N-linked oligosaccharides from proteins.
• Available in liquid and lyophilized formats.
• Works on native glycoproteins and serum glycoproteins, in minutes, at RT.
• Higher specificity towards complex sialylated structures.
• Excellent for use in high-end use applications such as UPLC/HPLC, HILIC, and/or MALDI-Glycan Mass Spec Imaging.
• Released glycans can be easily examined following labeling.
• Imaging of released glycans directly on tissue can be done following spraying of enzyme on tissue and incubation at 37°C for 1 hour.

Click here to see recent publications: https://lnkd.in/dgQs5S4

Click here to request a Quote: https://lnkd.in/dD-acXP

https://conta.cc/3xoyrox

Do you use a 2x PCR Master Mix? TaqDog is now available as a master mix Call Us Today! 603-570-4248 Request A Quote Meet the newest member of our TaqDog family What a strange and challenging year this is shaping up to be -- product

AcquaStain Protein Gel Stain: Simple, Fast, Sensitive & Reusable

AcquaStain is a 1-step Coomassie blue protein gel dye. That's right! No pre-washes. No destaining. Just run your protein gel, add the stain, and watch your bands appear in just a few minutes. Unlike many other stains, AcquaStain is a water-based product, which means that it causes no observable shrinkage or wrinkling of the gel. Better yet, unlike methanol-based stains, proteins isolated from AcquaStain-treated gels are 100% compatible with mass spectrometry analysis or other post gel applications. And did we mention you can save money by reusing it at least 3 times?

Below is a gel from one of our customers. Most customers say AcquaStain is significantly more sensitive than standard Coomassie protocols. Ask for a FREE sample here: https://lnkd.in/dihKX-m

Happy Birthday Bulldog Bio!
This month marks our 12th anniversary. What started in 2009 as a small “garage” company has grown! With offices in MA, NY and NH, our sales admin, tech and product support teams continue to expand. Lots of progress, yet we feel we’ve managed to uphold a friendly “Mom and Pop” vibe. Heartfelt thanks to each and every customer and trusted partner. With you we’ve reached this milestone. We’ve withstood the headwinds of 2020 and put the wind at our backs for 2021!!
Supporting your Science!

Neutralize Toxic Ethidium Bromide.

EtBr Destroyer is formulated to break-down ethidium bromide into a non-toxic and non-mutagenic bi-product. Available in two convenient formats for treatment of both solid and liquid ethidium bromide contaminants. EtBr Destroyer Bags are ideal for the treatment of liquid solutions or agarose gels that contain ethidium bromide. The EtBr Destroyer Sprayer is used to decontaminate solid surfaces that have been exposed to ethidium bromide including electrophoresis gel boxes, glassware, laboratory equipment, and bench surfaces.

Click here to request a Trial Quote: https://www.bulldog-bio.com/product/etbr-destroyer/

Do you use SuperScript II?

Do you use SuperScript II? Try our new RT enzyme for half the price Call Us Today! 603-570-4248 Request A Quote If you like SuperScript™ II* then you'll love Scriptase II You may recall seeing a similar eNewsletter from us for

FastGene Scriptase II: Longer cDNAs, Less Time, Half the Price

This high-quality reverse transcriptase is an optimized, drop-in replacement for SuperScript™ II. Reduces typical incubation times from 50 minutes to as little as 5 minutes. We've got your experiments covered with three convenient formats: Enzyme-only, complete cDNA synthesis kit and an easy-to-use master mix. Take your cDNA projects to a new level -- and for half the price.

Click here to request a Trial Quote: https://www.bulldog-bio.com/product/fastgene-scriptase-ii/

See Comparative Analysis Technical Note:https://www.bulldog-bio.com/wp-content/uploads/2019/09/LS53_FG-Scriptase-II_AN_2018_19.pdf
See Nature Biomedical Engineering publication from 2020, for SARS-CoV-2 detection, using Scriptase II to make template for qPCR: https://www.nature.com/articles/s41551-020-00654-0

Realize the new possibilities with Nano-Secondary Antibodies.
Nanobodies are small and powerful Camelidae antibody fragments. Hundreds of published papers have shown that these tiny binding proteins outperform classic monoclonal antibodies in just about every measurable way. Nano-Secondary Antibodies are the newest development in Nanobody research; roughly 10 times smaller than conventional secondary antibodies, this compact size enables better tissue pe*******on and decreases the distance between epitope and label. Their ultra-tight binding even allows you to add Nano-Secondary Antibodies directly to primary antibodies, before treating the sample -- thus eliminating steps and washes.

Read here to learn how these tiny and highly specific secondary antibodies will dramatically improve your lab's everyday immuno-assays: https://www.bulldog-bio.com/product/nano-secondary-antibodies/

TaqDog, a researcher's Best Friend.
Adopt a Premium TaqDog -or- Hot Start TaqDog PCR enzyme today, and experience the warm and fuzzies of amplified savings at just a few pennies per unit. Made for everyday PCR, Genotyping, qPCR, and high-volume PCR processing.

Stop paying too much for PCR. All of Bulldog Bio's PCR enzymes are priced fairly and promise satisfying results. It's that simple. Just ask us for a FREE sample and find out for yourself: https://www.bulldog-bio.com/product/taqdog-premium-taq-dna-polymerase/