Sarcoidosis Research

NIH
Scientists develop a simple blood test to quickly diagnose sarcoidosis
February 22, 2024, 9:00 AM EST

A research project supported by the National Institutes of Health has developed a tool to rapidly and inexpensively diagnose sarcoidosis, a chronic inflammatory disease marked by the growth of tiny lumps called granulomas in the lungs and other organs in the body. The tool, which uses a simple blood test, could allow for selective use of more invasive diagnostic tests often used to identify the disease. The findings published in the American Journal of Respiratory and Critical Care Medicine.

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Scientists develop a simple blood test to quickly diagnose sarcoidosis Sarcoidosis is hard to diagnose but scientists have now developed a simple blood test that can diagnose sarcoidosis, an inflammatory condition that primarily impacts the lung.

We must never forget that Black History is American History‼️

Happy New Year 2024!

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Who’s Natural!

Creamy Crack Be Gone:

FDA Proposes To Ban Relaxers But Watch How Companies Advertised To Black Women For Years

That “creamy crack” could be leaving the shelves according to a new proposal set forth by the U.S. Food and Drug Administration (FDA). The proposal would ban relaxers, which have been used primarily amongst Black women within the cosmetic industry for many years. Read more on why the FDA is proposing this change now and check out commercials with the harmful products, which were directly advertised to Black women.

The FDA is shaking up the beauty industry with a proposed ban on chemical hair-straightening products that are filled with health-compromising chemicals such as formaldehyde, which is used in glues and resins, dyes, textiles, disinfectants, building materials, automobile parts, embalming, and laboratories. Reports came out publicly in May sharing the links between straightening products and health risks like uterine, breat and ovarian cancer. (More in link)

Creamy Crack Be Gone: FDA Proposes To Ban Relaxers But Watch How Companies Advertised To Black Women For Years Relaxers could be leaving the shelves according to a new proposal set forth by the FDA. Watch commercials advertised to Black women inside.

Krayzie Bone Shares Health Update Amid Hospitalization:

‘Just Fought for Life’
The Bone Thugs-n-Harmony rapper was reportedly hospitalized nine days ago for complications related to sarcoidosis, an inflammatory disease

“Just fought for life literally for 9 days straight,” Henderson wrote on Instagram in his first post since the medical scare. “And I only won the battle this time because I know Jehovah God was with me every step of the way fighting for me.”

Krayzie Bone Shares Health Update Amid Hospitalization: 'Just Fought for Life' The Bone Thugs-n-Harmony rapper was reportedly hospitalized nine days ago for complications related to sarcoidosis, an inflammatory disease

HOME · HEALTH AND WELLNESS
Health Matters: Understanding Sarcoidosis – Here’s What You Need To Know About The Disease

AS BONE-THUGS-N-HARMONY’S ANTHONY HENDERSON BATTLES WITH THE CONDITION, PEOPLE ARE CURIOUS ABOUT THE DISEASE THAT HAS LEFT HIM FIGHTING FOR HIS LIFE.

Health Matters: Understanding Sarcoidosis – Here’s What You Need To Know About The Disease | Essence As Bone-Thugs-N-Harmony’s Anthony Henderson battles with the condition, people are curious about the disease that has left him fighting for his life.

ABILITIES IN MOTION

2023 Adapted Sports Day
Saturday, September 23 | 8AM -3PM

Adapted Sports Day is a FREE event hosted by the Harris County - Houston Sports Authority in partnership with TIRR Memorial Hermann. Adapted Sports Day provides an opportunity to both youth and adults with physical disabilities to experience a variety of Adapted Sports. We encourage first time participants to come out and try pickleball, swimming, and more! It will be a fun day filled with educational and training opportunities.

Who can participate?
Adapted Sports Day is an opportunity for youth and adults with physical disabilities to experience a variety of Adapted Sports. If you or someone you know has a physical disability, we encourage you to click HERE to find out more about the event.

Participants Wanted - Free Adapted Sports Event Adapted Sports Day is a FREE event hosted by the Harris County - Houston Sports Authority in partnership with TIRR Memorial Hermann. Adapted Sports Day provides an opportunity to both youth and adults with physical disabilities to experience a variety of Adapted Sports. We encourage first time parti...

Treatment is not one size fits all’: Sarcoidosis management must be individualized

‘Treatment is not one size fits all’: Sarcoidosis management must be individualized DESTIN, Fla. — Complicated disease pathogenesis and a lack of FDA-approved therapies makes sarcoidosis a significant clinical challenge, according to a presenter at the 2023 Congress of Clinical Rheumatology-East.“Sarcoidosis is a chronic disease of unknown etiology,” Nadera Sweiss...

Ignore No More': Actress Pushes for Research on Rare Inflammatory Disease

Actress Jeryl Prescott Gallion is working to get more African Americans into clinical trials for Sarcoidosis. News4 Community Reporter Molette Green reports on her push for Congress to pay attention to the disease.

‘Ignore No More': Actress Pushes for Research on Rare Inflammatory Disease Actress Jeryl Prescott Gallion is working to get more African Americans into clinical trials for Sarcoidosis. News4 Community Reporter Molette Green reports on her push for Congress to pay attention to the disease.

Do you know what Sarcoidosis is? A Houston-area mom didn't, until her beloved daughter passed away from it 20 years ago.
Melinda Wilson

Emma Carroll has spent all these years running a foundation in her daughter's name to raise awareness through Janine's Sarcoidosis Outreach Foundation. "My daughter became ill, and we had no idea what her illness was, but when she finally got a diagnosis on a Monday, she died the next Monday at 31-years-old from a disease that we were told was sarcoidosis, something we had never heard of. (Please click the link for more)

Walk to fight, spread awareness of Sarcoidosis in Bellaire this weekend Get ready to lace up your shoes as it’s going to be a beautiful weekend to walk for a worthy cause.

Don’t forget to register for the April Sarcoidosis Awareness Month Walk in Houston Texas April 29th. Www.Jsof.org

https://d-mars.com/event/april-is-sarcoidosis-awareness-month-walk-for-a-cure/

April is Sarcoidosis Awareness Month! | Walk For A Cure! - d-mars.com HOUSTON, TEXAS APRIL 1, 2023 – In observance of April as International Sarcoidosis Awareness Month, Janine’s Sarcoidosis Outreach Foundation & Support Group (JSOF) will host its annual Sarcoidosis Awareness 5K...

APRIL SARCOIDOSIS AWARENESS MONTH PURPLE CHALLENGE!!
www.Jsof.org


April Challenge list. Choose any number for any day!

1. Paint fingernails Purple
2. Wear Purple bottoms
3.Paint your hair with Purple streaks
4. Wear Purple shoes
5. Make a Wreath of Purple and place on your door.
6. Wear a Purple hat
7. Make a sign and place in back of car saying April belongs to Sarcoidosis Awareness
8. Wear a Purple Tie
9. Purple lipstick
10. Purple outfit
11. Large Purple earrings
12. Guest towels Purple
13. Buy a Purple Pillow
14. Draw a Snowflake, put your name on it, or a Fallen Snowflake
15. PURPLE WELCOME RUG
16. Display a Purple Ribbon
17. Change your profile picture temporarily to:

https://houston.culturemap.com/eventdetail/janine-sarcoidosis-outreach-foundation-presents-walk-for-a-cure/

Janine Sarcoidosis Outreach Foundation presents Walk For A Cure The Janine Sarcoidosis Outreach Foundation presents Walk For A Cure. Sarcoidosis affects men, women and children of all races. Sarcoidosis is a multi-system disorder that affects the lungs and intrathoracic lymph nodes.

Extrapulmonary Sarcoidosis With Multi-Organ Involvement Presenting Primarily as Hypercalcemia

Published: January 09, 2023 (see history)

Sarcoidosis is a highly variable disease. The majority of cases affect the lungs, but they can involve other organs as well. Extrapulmonary sarcoidosis is rare, and it can present in many ways. Therefore, the diagnosis can be challenging. We hereby present a case of a patient presenting with hypercalcemia and diagnosed with extrapulmonary sarcoidosis with multi-organ involvement. This article was previously presented as a meeting abstract at the MI-ACP 2022 Annual Scientific Meeting on October 14, 2022.

Introduction

Sarcoidosis is a highly variable, granulomatous disease. It most commonly affects females below 40 years of age [1]. Over 90% of the time, there is pulmonary involvement [2]. However, it is well documented that there are a variety of ways that sarcoidosis can present with extrapulmonary involvement. Mediastinal and hilar lymphadenopathy followed by cutaneous involvement is the most common extrapulmonary presentation [1]. African Americans are disproportionately affected by extrapulmonary manifestations [3].

Sarcoidosis is a diagnosis of exclusion. The major diagnostic criteria are as follows: compatible clinical presentation, finding non-necrotizing granulomatous inflammation in one or more tissue samples, and the exclusion of alternative causes of granulomatous disease [4]. Other causes of granulomatous disease that must be ruled out include lymphoproliferative disorders such as Hodgkin’s lymphoma and infectious diseases including leishmaniasis, toxoplasmosis, and tuberculosis [5].

Cutaneous sarcoidosis is described as specific or non-specific. Erythema nodosum is recognized as the most common non-specific skin manifestation of sarcoidosis. It can present as erythematous macules, papules, plaques, or subcutaneous nodules. It may also occur in scar tissue, at traumatized sites, and around embedded foreign bodies, such as tattoos. Reactions to tattoos may form in response to one or more colors within a tattoo and can develop even years after the placement of the tattoo [5-6]. These changes may even be seen in imaging, which is often used to evaluate the involvement of sarcoidosis. They appear as soft-tissue nodules or masses in the subcutaneous planes with low signal intensity on T1-weighted imaging and high signal intensity on T2-weighted imaging. Cutaneous findings should be taken as an opportunity to evaluate for systemic disease [7].

Sarcoidosis can also present with renal involvement, presenting as granulomatous interstitial nephritis and hypercalcemia [6,8]. Other extrapulmonary findings include ocular manifestations, most commonly uveitis. In addition, in the workup of lymphoproliferative disorders, granulomas can be seen on bone marrow biopsy, which is uncommon but documented in case reports [9]. Parotid gland enlargement can be seen on imaging and is usually bilateral. It is present in 6% of cases [10]. Other rare manifestations include splenomegaly, muscular involvement, and hepatic involvement.

The mainstay of treatment for all manifestations of sarcoidosis continues to be corticosteroids. In the setting of cutaneous sarcoidosis, topical corticosteroids can be used as well. Of note, methotrexate and antimalarials such as chloroquine and hydroxychloroquine have been shown to be good treatment options for cutaneous sarcoidosis and hypercalcemia [6]. (Please click the link for more)

https://www.cureus.com/articles/125849-extrapulmonary-sarcoidosis-with-multi-organ-involvement-presenting-primarily-as-hypercalcemia

Extrapulmonary Sarcoidosis With Multi-Organ Involvement Presenting Primarily as Hypercalcemia Sarcoidosis is a highly variable disease. The majority of cases affect the lungs, but they can involve other organs as well. Extrapulmonary sarcoidosis is rare, and it can present in many ways. Therefore, the diagnosis can be challenging. We hereby present a case of a patient presenting with hyperca...

Study shows a changed microbiome in the lower airways for sarcoidosis patients

Study shows a changed microbiome in the lower airways for sarcoidosis patients Sarcoidosis is a systemic inflammatory disease that is difficult to diagnose and treat, partly because its cause and mechanism remain unclear.

UTHealth Houston
McGovern Medical School
Clinics for Sarcoidosis

What is Sarcoidosis?

Sarcoidosis is an inflammatory disease that affects many different organs of the body. It mostly affects the lungs and the lymph nodes. People who are diagnosed with sarcoidosis usually present with lumps called granulomas. Occasionally, sarcoidosis is referred to as simply “sarcoid.”

The symptoms vary widely depending on the organs involved. Not all organs are affected at the same time with sarcoidosis. There are many people with sarcoidosis who live healthy, happy, and active lives. Many do not have daily symptoms. Others have symptoms that develop and worsen over time.

Patients mostly complain of persistent dry cough, fatigue and shortness of breath, especially when the lungs are involved. The exact cause of sarcoidosis is still unknown but its manifestations show an association of autoimmune response from unknown triggers. In other words, the person’s own immune system may be involved.

The Clinics for Sarcoidosis

At the Clinic for Sarcoidosis at the Texas Medical Center in Houston, Texas, we are committed to improve the lives of our patients. Our priorities are to alleviate their symptoms and improve the function of everyday lives. Quality of life is very important to us. We seek to coordinate patient care with other specialist physicians depending on the organs that are affected by the sarcoidosis condition.

As part of an academic tertiary referral center, our Clinic for Sarcoidosis offers state of the art, evidence-based management of sarcoidosis.

For more information on our Clinics for Interstitial Lung Disease (ILD), click here.

Mission of Clinics of Sarcoidosis

We break down our mission statement into four key focus areas: clinical care, community, education, and research. (Please click the link for full article)

Clinics for Sarcoidosis - Department of Internal Medicine Sarcoidosis. The UT physicians who are leading the Clinics for Sarcoidosis is Dr. Pascal Kingah. Dr. Pascal Kingah and Dr. Rahat Hussain are at McGovern Medical School at UTHealth. Make your appointment today.

The Bernie Mac Foundation Presents - The "Kick It" Comedy Show Fundraiser

A Fundraising Celebration with Comedy, Food, Cocktails and Great Vibes with The Bernie Mac Foundation!

By
The Bernie Mac Foundation
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When and where
Date and time
Wed, October 26, 2022, 6:00 PM – 9:00 PM CDT
Location
200 W Madison St 200 West Madison Street Chicago, IL 60606

Come celebrate with The Bernie Mac Foundation for the birthday of the late Bernie Mac! You'll enjoy stand-up comedy with Comics Leon Rogers, Jeff B, and Jeremy Unmask. Located at a beautiful venue in downtown Chicago, you will be served delicious hors d'oeuvres and a complimentary cocktail.

During our cocktail hour you'll hear sounds by DJ Zulu.ish and be able to check out our vendors tables. Everyone will have a chance to enter our raffle to win cool items and a % of the pot! Following our cocktail hour will be a comedy show that you won't want to miss!

The purpose of this event is to help The Bernie Mac Foundation raise funds for sarcoidosis research and also to celebrate the birthday and life of a Chicago comedian whose life was taken too soon, Bernard "Bernie Mac" McCullough.

This will be a night that you won't forget, and we can't wait to celebrate it with you!
Proceeds will help fund The Bernie Mac Sarcoidosis Translational Advanced Research (STAR) Center at UI Health here in Chicago, IL.**

The Bernie Mac Foundation Presents - The "Kick It" Comedy Show Fundraiser A Fundraising Celebration with Comedy, Food, Cocktails and Great Vibes with The Bernie Mac Foundation!

1st Patient Dosed in Trial of Pulmonary Sarcoidosis Treatment... The Phase 3 trial is testing efzofitimod's ability to improve lung function, reduce corticosteroid use in adults with pulmonary sarcoidosis.