Wyss Center for Bio and Neuroengineering, Geneva Videos

📰News round-up! In this issue we welcome our new Head of Business Development and Licensing, invite you to our Wyss Center Brain Health Symposium and share a new exciting job opportunity as Head of R&D at the Wyss Center; and much more! 💥 Read and subscribe here: https://wysscenter.ch/newsletter #neurotechnology #neuroscience #innovation

In support to @savesightnoweurope in their commitment to curing childhood blindness, Wyss Center teams are running @GeneveMarathon this Sunday in Geneva. Good luck to all the runners as they help raise awareness of #ushersyndrometype1b. Thousands of children around the world are born with hearing and balance problems due to Usher Syndrome Type 1B. They will also lose their sight during their childhood years due to the degeneration of the retina caused by Retinitis Pigmentosa. @SaveSightNowEurope and @SaveSightNow work tirelessly with families on both sides of the Atlantic to support and enhance scientific research so that a cure for Usher 1B Syndrome can be found as soon as possible. #GeneveMarathon #savesightnoweurope #savesightnow Find out more: https://www.savesightnoweurope.org/

🌟📽 New video 🧠 3D spatial transcriptomics may hold clues to future therapies for brain diseases. The technique measures gene expression from the RNA found in cells. It tells us what type of cell it is, exactly where it is, and can also indicate how a cell may interact with neighboring structures to the sides, above or below. 🔬 Imaging performed with spinning disk microscopy. For more information about our microscopy facility: https://wysscenter.ch/facilities/alice #lightsheet #microscopy #brain #neuroscience #transcriptomics

Our fifth and final #Brainawarenessweek video is a sneak peak of our new 3D spatial transcriptomics film – coming soon, stay tuned. 3D spatial transcriptomics is a technique that measures gene expression from the RNA found in cells. It tells us what type of cell it is and exactly where in the sample the cell is. The technique could reveal crucial characteristics of brain diseases that may hold the key to future therapies. Every day this week we are sharing short videos that shed light on an emerging suite of lab techniques that are helping to accelerate development of therapies for brain disorders. Campus Biotech #brainweek #brainawarenessweek2023 #neuroscience #microscopy

Our fourth #Brainawarenessweek video: Creating elastic brain samples. The ELAST technique helps fluorescent 'tags' penetrate samples more deeply making structures in thicker brain sections visible under a microscope. Every day this week we are sharing short videos that shed light on an emerging suite of lab techniques that are helping to accelerate development of therapies for brain disorders. #brainawarenessweek2023 #brainweek #neuroscience #microscopy

Expansion microscopy
In our third #Brainawarenessweek video, we explain how to physically expand a brain sample to allow as much information as possible to be extracted from the tissue. Expansion microscopy deepens our understanding of disease mechanisms to accelerate development of therapies for neurological and psychiatric disorders. #brainweek #brainawarenessweek2023 #brain #neuroscience

How to optically slice brain samples with a sheet of light. Introducing #lightsheet #microscopy. Every day this #brainawarenessweek2023 we are sharing videos to shed light on techniques that are accelerating development of therapies for brain disorders. @campusbiotech @danafoundation #brainawarenessweek #BrainWeek Find out more: https://wysscenter.ch/facilities/alice

#brainawarenessweek2023 kicks off today and we are joining partners around the world in a celebration of brain science. Every day this week we will be sharing short videos that shed light on lab techniques that are helping to accelerate development of therapies for brain disorders. First up, ‘Creating transparent brains’, a 55 second introduction to preparing brain samples for imaging with lightsheet microscopes. #BrainWeek #BrainAwarenessWeek Campus Biotech Dana Foundation Brain Awareness Week Find out more about lightsheet imaging: https://wysscenter.ch/facilities/alice

❤️ Thanks to our prototyping lab team for this laser cut #Valentine’s Day heart ❤️ Our prototyping laboratories enable the design, fabrication and optimization of novel devices and #technologies to improve the lives of people with nervous system disorders. It is here that innovative concepts move from initial idea to realistic technology - @Campus Biotech. Find out more:

Season’s greetings! 🎄 This fantastically festive #lightsheet #microscopy image shows the neuronal network that surrounds the gut. Colour represents the strength of the fluorescent signal from the gut neurons. The NeuroGI team is investigating how #neurons are involved in gut function and how their connection with the #brain could inspire novel treatments for brain disorders. (Festive sparkles do not represent data.) Subscribe to keep up-to-date with all our news in 2023: https://wysscenter.ch/newsletter

🌟 What better time of year to launch our STAR project - Solutions Through Astrocyte Research! Could the long-overlooked star-shaped astrocyte be a secret weapon against diseases like Alzheimer’s? Find out how the STAR team is pursuing new strategies to identify #biomarkers and new therapeutic targets to treat #neurological and psychiatric disorders. Astrocytes make up at least 30% of brain cells and use chemical signals - changes in their intracellular calcium (Ca2+) concentration - to communicate among themselves and with other nearby cells, including neurons. This video shows 3D Ca2+ signaling in a single astrocyte. https://wysscenter.ch/advances/star #brain #therapy #neuroscience

📽 Expansion microscopy: Expanding gel physically increases the size of #brain 🧠 samples, allowing intricacies to be visualized. The technique deepens understanding of disease mechanisms to accelerate development of #therapies for neurological and psychiatric disorders. For more info and full video visit: https://wysscenter.ch/facilities/alice#section-expansion-microscopy-visualizing-the-intricacies-of-the-brain Campus Biotech

📽 Expansion microscopy: Movie shows expanding gel physically increasing the size of a #brain sample 🧠 The technique allows the intricacies of the brain to be visualized and more information to be extracted, revealing disease mechanisms and accelerating development of therapies for neurological and psychiatric disorders, like Parkinson’s and Alzheimer’s diseases. Full video 📽 and details about the team, 🧖‍♀️ 🧖‍♂️ collaborators and capabilities 🔬 here: https://wysscenter.ch/facilities/alice#section-expansion-microscopy-visualizing-the-intricacies-of-the-brain

Latest neural signals recorded with ABILITY brain-computer interface. New data and details will be announced in a series of poster presentations at #SfN22. ABILITY is being developed to restore movement & communication for people with severe paralysis. Meet the team and see the ABILITY device @Society for Neuroscience exhibition booth number: 3117 @societyforneuroscience https://wysscenter.ch/updates/latest-neural-signals-recorded-with-ability-brain-computer-interface-and-new-details-of-the-system-presented-at-society-for-neuroscience-meeting

Travel down the gut and discover a second brain! This amazing new video reveals the gut’s own nervous system. It is the latest data from the team exploring the gut-brain connection in the quest to solve brain disorders. Captured with lightsheet microscopy the images show a section of mouse colon in 3D with tissue structures (blue) and the neuronal network that surrounds the gut (pink). The team is unveiling the shape, size and organization of the enteric nervous system and is developing a micro-endoscopic device to further explore gut-brain dynamics in health and disease. The project has received funding from the European Research Council (ERC). Find out more here: https://wysscenter.ch/advances/neurogi

Congratulations to the NeuroRestore team & co-first author Kyuhwa Lee - now Machine Learning Scientist at the Wyss Center - on their new paper published today in @ScienceMagazine (Translational Medicine). Exciting prospects for these results to improve walking in people with Parkinson’s disease. https://www.science.org/doi/10.1126/scitranslmed.abo1800

🌟 New project: Exploring the gut-brain connection in the quest to solve #brain disorders with @Inserm and @unistra First data - architecture of the colon thanks to lightsheet microscope images of clarified mouse gut in cross-section More: https://wysscenter.ch/advances/neurogi

This International Women in Engineering Day #INWED22 we highlight Wyss Center Project Manager, Shenandoah Montamat. Shenandoah is leading the exciting and innovative #neuroengineering project - ABILITY - a brain-computer interface system under development to enable applications such as restoration of communication and movement for people with severe paralysis. We believe that the strongest teams are built on diversity. We bring together people of different genders, from different disciplines and with different backgrounds to encourage creative thinking, drive progress and ultimately deliver results. In this new video, Shenandoah reveals her first invention at the age of five and describes the ABILITY team’s shared dream. https://wysscenter.ch/multimedia#section-where-i-work-the-shared-dream-of-the-ability-team Inwed1919 Campus Biotech

Congratulations to the Wyss Center relay #marathon finishers! This year, 16 Wyss Center runners took part in @GeneveMarathon. Look back on an exciting day with ups, downs, emotions & fantastic #team spirit! Full video: https://wysscenter.ch/join-our-team#section-congratulations-to-the-wyss-center-relay-marathon-finishers

📽️📺 New interview and video! Research technician Ivana Gantar explores the hidden microscopic world of 🧠s with #lightsheet microscopes. “I'm already pushing the limits of what I thought I could image. I think this describes the Wyss Center - you're always pushing a little bit beyond what you expect and what you imagined you could do.” 🧠 Check out the video and full interview: https://wysscenter.ch/updates/where-i-work-seeing-the-invisible 🧠 Thanks to @mariondevevey for multimedia production Campus Biotech