Videos by Mazindol ER in Narcolepsy in Zürich. The POLARIS clinical development program is being conducted by NLS Pharmaceutics.
NLS Pharmaceutics is presenting interim top-line data on the phase 2a study in narcoleptic patients at the World Sleep Congress in Rome today March 16, 2022, 12:30pm - 2:00pm (CET).
#worldsleep2022 #narcolepsy #worldsleepsociety #forbetterhealth #cns #cataplexy #narcolepsyawareness
NLS Pharmaceutics at World Sleep 2022
NLS Pharmaceutics is presenting interim top-line data on the phase 2a study in narcoleptic patients at the World Sleep Congress in Rome today March 16, 2022, 12:30pm - 2:00pm (CET).
#worldsleep2022 #narcolepsy #worldsleepsociety #forbetterhealth #cns #cataplexy #narcolepsyawareness
How does mazindol work?
Mazindol has a dual action:
• It acts as a partial Orexin 2 Receptor Agonist that may help replace the missing #orexin (endogenous orexin peptide), addressing the underlying cause of #narcolepsy;
• It also acts as a reuptake inhibitor of #dopamine, #norepinephrine, and #serotonin, that can further reduce disease specific symptoms.
A proprietary extended-release formulation of mazindol (mazindol ER) is being evaluated by NLS Pharmaceutics in the POLARIS Clinical Development Program in adult subjects suffering from narcolepsy.