Mazindol ER in Narcolepsy

The POLARIS clinical development program is being conducted by NLS Pharmaceutics.

16/03/2022

NLS Pharmaceutics is presenting interim top-line data on the phase 2a study in narcoleptic patients at the World Sleep Congress in Rome today March 16, 2022, 12:30pm - 2:00pm (CET).

Current and Emerging Therapy and the Potential to Address the Orexin Deficit by Dr. Helene Emsellem 07/02/2022

Watch Dr. Helene Emsellem's presentation at the International Narcolepsy Webinar by Wake Up Narcolepsy.
"Current and Emerging Therapy and the Potential to Address the Orexin Deficit" - a presentation on generally, including a discussion of mazindol as a potential treatment for narcolepsy and NLS Pharmaceutics ongoing phase 2 clinical trial for mazindol ER.

Current and Emerging Therapy and the Potential to Address the Orexin Deficit by Dr. Helene Emsellem During the Wake Up Narcolepsy International Narcolepsy Webinar January 20 - 21, 2022, attendees heard the latest from narcolepsy researchers, patient advocat...

Swiss Narcolepsy Day - Sponsored Symposium NLS Pharmaceutics 03/02/2022

Take a look at NLS Pharmaceutics' symposium "Swiss Innovation in Sleep Disorders" at the 7th Swiss Narcolepsy Day, featuring C. Camozzi, MD (Medical Director NLS) and S. Panigone, PhD, EMBA (COO NLS).

Swiss Narcolepsy Day - Sponsored Symposium NLS Pharmaceutics Sponsored Symposium NLS Pharmaceutics, Swiss Innovation in Sleep Disorders C. Camozzi, MD - Medical Director NLS S. Panigone, PhD,EMBA - COO NLS

International Narcolepsy Webinar - January 2022 - Wake Up Narcolepsy 19/01/2022

NLS Pharmaceutics Invites Patients, Caregivers and Other Interested Parties to Attend International Narcolepsy Webinar - Wake Up Narcolepsy

A presentation discussing generally, including a discussion of mazindol as a potential treatment for narcolepsy and NLS Pharmaceutics ongoing phase 2 clinical trial for mazindol ER will take place at 12:45pm ET (6:45pm CET) on January 20, 2022.

To join the Webinar, follow the link here:
http://ow.ly/namF50HxxH9

International Narcolepsy Webinar - January 2022 - Wake Up Narcolepsy Wake Up Narcolepsy invites you to attend their FREE International Narcolepsy Webinar on Thursday, January...

04/01/2022

9 facts about

03/01/2022

in

03/01/2022

Did you know?
There is an average of 8 – 15 years between symptom onset and diagnosis.



Source: www.project-sleep.com

02/01/2022

How is diagnosed?

Source: https://www.wakeupnarcolepsy.org/

Photos from Mazindol ER in Narcolepsy's post 02/01/2022

Narcolepsy is a severe rare disease with unmet medical need.



Learn more at https://knownarcolepsy.com/hcp/impact

Source: National Know Narcolepsy Survey, 2018.

02/01/2022

Did you know?
 Based on the presence of , can be classified into two variants.

01/01/2022

What is ?

International Narcolepsy Webinar - January 2022 - Wake Up Narcolepsy 31/12/2021

Hear the latest advancements from researchers, advocates,
and individuals with from across the globe at the International Narcolepsy Webinar by Wake Up Narcolepsy in Jan 2022.

https://www.facebook.com/wakeupnarcolepsy

https://www.wakeupnarcolepsy.org/news/international-narcolepsy-webinar/

International Narcolepsy Webinar - January 2022 - Wake Up Narcolepsy Wake Up Narcolepsy invites you to attend their International Narcolepsy Webinar on Thursday, January 20...

People with Narcolepsy are Often Misunderstood – Emily’s Story 30/12/2021

The impact of and in



https://www.youtube.com/watch?v=TUyVyOL8s7s

People with Narcolepsy are Often Misunderstood – Emily’s Story Emily knows those living with narcolepsy are no different from anyone else. Listen to her story as she shares how narcolepsy symptoms can be mislabeled by ot...

30/12/2021

Excessive Daytime Sleepiness (EDS) is the main symptom of .

Photos from Mazindol ER in Narcolepsy's post 29/12/2021

Symptoms of include:

Hallucinations around sleep
Disrupted nighttime sleep
Brain fog

Photos from Mazindol ER in Narcolepsy's post 29/12/2021

Symptoms of include:

Excessive Daytime Sleepiness

Cataplexy
Sleep paralysis

What is Narcolepsy? 28/12/2021

Understanding how develops: how the dysfunction affects the brain.



https://www.youtube.com/watch?v=Ucpf_OYvs4E

What is Narcolepsy? Dr. Tom Scammell, Professor of Neurology at Harvard Medical School and a Sleep Medicine specialist provides an overview of narcolepsy. He discusses the sympt...

Photos from Mazindol ER in Narcolepsy's post 22/12/2021

What is ?

Narcolepsy is a chronic neurological condition that impairs the brain's ability to regulate the sleep-wake cycle.

20/12/2021

NLS Initiates Phase 2 Trial for Quilience in Narcolepsy and Announces First Patient Enrolled

Read the press release: https://bit.ly/3eer9vu

17/12/2021

Mazindol has a dual action:

• It acts as a partial Orexin 2 Receptor Agonist that may help replace the missing (endogenous orexin peptide), addressing the underlying cause of ;

• It also acts as a reuptake inhibitor of , , and , that can further reduce disease specific symptoms.

A proprietary extended-release formulation of mazindol (mazindol ER) is being evaluated by NLS Pharmaceutics in the POLARIS Clinical Development Program in adult subjects suffering from narcolepsy.

NLS Pharmaceutics Announces New Study Data Confirming Mazindol's Unique Orexin Pathway Activation for Treating Narcolepsy 17/12/2021

NLS Pharmaceutics Announces New Study Data Confirming Mazindol's Unique Pathway Activation for Treating .

Learn more about mazindol at https://polaris.nlspharma.com/mazindol-er/

NLS Pharmaceutics Announces New Study Data Confirming Mazindol's Unique Orexin Pathway Activation for Treating Narcolepsy /PRNewswire/ -- NLS Pharmaceutics Ltd. (Nasdaq: NLSP, NLSPW) ("NLS" or the "Company"), a Swiss clinical-stage pharmaceutical company focused on the discovery...

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