Complex Disease Epigenetics Group

The group have been busy writing in lockdown - here is a review article we have just published on epigenetic research in different dementias.

https://link.springer.com/article/10.1007/s40142-020-00190-y?wt_mc=Internal.Event.1.SEM.ArticleAuthorOnlineFirst

Exploring Beyond the DNA Sequence: A Review of Epigenomic Studies of DNA and Histone Modifications in Dementia Although genome-scale studies have identified many genetic variants associated with dementia, these do not account for all of disease incidence and so recently attention has turned to studying mechanisms of genome regulation. Epigenetic processes such as modifications to the DNA and histones alter t...

We enjoyed compiling a mini-symposium on the molecular etiology of Alzheimer’s disease, featuring some really interesting articles from experts in the field. Check it out on our twitter link 👇

https://twitter.com/katielunnon/status/1282974591539802117?s=21

Professor Katie Lunnon on Twitter “Really enjoyed turning hand to editing and putting together this mini symposium series on the molecular etiology of AD! Some really interesting articles from experts in the field in the series, check it out below👇 https://t.co/cwDJZr19eU”

Our latest paper identifying epigenetic changes in the blood in patients with Alzheimer's disease or mild cognitive impairment is out now! University of Exeter Medical School
https://www.sciencedirect.com/science/article/pii/S0197458020302165

An epigenome-wide association study of Alzheimer’s disease blood highlights robust DNA hypermethylation in the HOXB6 gene A growing number of epigenome-wide association studies have demonstrated a role for DNA methylation in the brain in Alzheimer’s disease. With the aim …

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Complex Disease Epigenetics Group updated their business hours.