Alison Sheldrick

This study, I hope, will start a revolution in the way people diagnosed with Alzheimer’s are treated. It blows out of the water all the studies carried out with drugs which are ineffective as far as I can see. The dreaded beta amyloid, often touted as the cause of Alzheimer’s, is one of the ways the body protects the brain and this makes the drugs designed to remove it positively dangerous.

The symptoms of Alzheimer’s disease are the result of not one but many imbalances in the body caused by infections, toxins, inflammation, hormonal imbalances and poor diet and lifestyle to name a few. If we take care of these, as Professor Bredesen says, we can make Alzheimer’s a rare disease.

Don’t wait for a diagnosis. So much can be done if we start addressing these things early - the earlier the better. Why wait until the brain is damaged beyond repair? It could be just too late…

Analysis of ReCODE Protocol Effectiveness On the ReCODE Protocol, 51% of participants with SCI, MCI, and AD experienced significantly improved cognition.

https://www.genengnews.com/news/human-study-suggests-brain-tissue-inflammation-is-key-to-alzheimers-disease-progression/

Human Study Suggests Brain Tissue Inflammation Is Key to Alzheimer’s Disease Progression Findings indicate that targeting neuroinflammation might help to slow or even reverse tau protein accumulation in the brain, and stave off dementia.

I could listen to Dr Bredesen talk about his work all day!!
In this presentation he tells why drugs haven’t been effective in the treatment of Alzheimer’s and describes his first study showing the effectiveness of a precision medicine model to help treat Alzheimer’s. The results of the trial are dramatic.
Importantly, Dr Bredesen tells us not to wait for a diagnosis of Alzheimer’s. When you think something isn’t quite right, that’s the time to take action to stop the progression towards this horrible disease.

An interesting read.

The First Survivors of Alzheimer’s, and How They Recovered Life and Hope Why I decided to dedicate my career to helping patients rediscover fulfilling lives, rewarding relationships, and meaningful work.

Alison Sheldrick updated their business hours.

A brilliant read.

Flat-Earth Criticism of Alzheimer’s Success - Apollo Health Dr. Bredesen addresses his critics in a recent blog post

The post below is from Dr Bredesen who has developed a programme to prevent and reverse Alzheimer’s disease. It is important that we identify and address the underlying causes of Alzheimer’s and infections can be part of the pathogenesis of the disease. The underlying imbalances that can contribute to this awful disease can be identified decades before diagnosis so now is the time to start looking.

“We've long observed that specific types of infections, like HSV-1 (Herpes simplex 1, which causes cold sores), are associated with Alzheimer's pathogenesis. These infections stimulate the innate immune system to produce amyloid-beta, which has protective antimicrobial properties, in an effort to safeguard the brain. The great news is that many of these infections are treatable, and identifying them as early as possible presents another opportunity to intervene.” https://www.mdpi.com/2075-4426/10/3/74/htm

The Viral Hypothesis in Alzheimer’s Disease: Novel Insights and Pathogen-Based Biomarkers Early diagnosis of Alzheimer’s disease (AD) and the identification of significant risk factors are necessary to better understand disease progression, and to develop intervention-based therapies prior to significant neurodegeneration. There is thus a critical need to establish biomarkers which...

Dementia prevention, intervention, and care: 2020 report of the Lancet Commission The number of older people, including those living with dementia, is rising, as younger age mortality declines. However, the age-specific incidence of dementia has fallen in many countries, probably because of improvements in education, nutrition, health care, and lifestyle changes. Overall, a growi...

https://www.medicinenet.com/script/main/art.asp?articlekey=239088

Are Iron Stores the Key to Alzheimer's? - MedicineNet Health News The progression of Alzheimer's disease may accelerate as iron deposits build up in the brain, a new study finds, hinting at a possible role for the mineral in mental decline.

https://nutrition.bmj.com/content/early/2020/05/20/bmjnph-2020-000085

Nutrition, immunity and COVID-19 The immune system protects the host from pathogenic organisms (bacteria, viruses, fungi, parasites). To deal with this array of threats, the immune system has evolved to include a myriad of specialised cell types, communicating molecules and functional responses. The immune system is always active,....

'Diabolical Disease': COVID-19 Much More Than a Lung Disease Doctors report several non-respiratory conditions stemming from COVID-19.

Does the key to anti-ageing lie in our bones? Osteocalcin, a hormone produced in the bones, could one day provide treatments for age-related issues such as muscle and memory loss

Higher risk of dementia in English older individuals who are overweight or obese AbstractBackground. Several risk factors contribute to dementia, but the role of obesity remains unclear. This study investigated whether increased body weight

https://www.theguardian.com/society/2020/jun/23/scientists-link-bowel-inflammation-to-higher-risk-of-dementia

Scientists link bowel inflammation to higher risk of dementia Study is latest to find high degree of correlation between gut health and mental health

Makes sense!

Research shows that the symptoms of diseases like Alzheimer’s can be prevented and, in some cases, even reversed. This story illustrates this nicely. In many cases it will take more than just changing diet to get results. But now that many of the imbalances that contribute to Alzheimer’s are known we can, for the first time, feel empowered to fight it and get well again.

https://www.collective-evolution.com/2018/04/27/82-year-old-woman-with-dementia-gets-her-memory-back-after-changing-her-diet/

82-Year-Old Woman With Dementia Gets Her Memory Back After Changing Her Diet A message to our readers: Have you checked out our NEW on demand video platform called CETV? We created it to combat censorship and support the important journalism we are doing. Visit CETV.one to sign up for a free 7 day trial here. Thank you for your support! Recently, an 82-year-old woman who suf...

Dr Bredesen says it clearly enough below. Alzheimer’s can be prevented and in those people who have had their symptoms reversed and are living a normal life again, the results are sustained. Yes there is hope but hope alone won’t make a difference - we need to take action, be responsible for our own health and start early. Now is a good time. What changes could you make to improve your health?

September is World Alzheimer’s Month, and this year it is a time of HOPE. In fact, it may be time to consider changing Alzheimer’s Month from September to April, from autumn to spring. We have suffered a long, long Alzheimer’s Winter, and we are now seeing repeated examples indicating that the Alzheimer’s Winter is ending:

•“I could share countless examples of how she has gotten her life back.”
•“He passed his written driving test with a 100% score…He is able to paint again.”
•“He is a functioning person again.”
•“His short-term memory is 100% back.”
•“My neurologist cannot believe the results.”

These are from just 5 of hundreds of reports of improvement. We still have a long way to go to be able to help every person with cognitive decline, but this month is a good time to celebrate what has occurred so far:

•The first examples of the reversal of cognitive decline (2014).
•Identification of the subtypes of Alzheimer’s disease, allowing more precise
treatment (2015).
•Identification of toxin-induced Alzheimer’s disease (2016).
•Report of 100 patients with documented cognitive improvement (2018).

The first patients to adopt the ReCODE protocol have now sustained their
improvement for over 7 years, something that was inconceivable even a few years ago. With prevention and early treatment, it is now possible to make Alzheimer’s a rare disease. So even though it is September, the Alzheimer’s Spring is truly beginning.

I’ve just spent another amazing day listening to Professor Bredesen explain how to prevent and reverse cognitive decline and make Alzheimer’s a rare disease. Here he explains the inter connectivity between our metabolism and the amyloid precursor protein (APP). APP acts like a switch, either pushing us towards or away from developing Alzheimer’s disease.

Alzheimer’s disease can be prevented and reversed - here’s how

https://m.youtube.com/watch?v=AmXGhS1ebKU

Dr. Dale Bredesen Key Takeaways (Depression & Anxiety Secrets) Highlights from Jonathan Otto's interview with Dr. Dale Bredesen, for the Depression & Anxiety Series. Dr. Bredesen discusses Alzheimer's, the role of geneti...

https://www.bps.ac.uk/news-events/news/articles/2019/statins-linked-to-higher-diabetes-risk?_cldee=YnNjQGJvYnNoZWxkcmljay5jb20%3d&recipientid=contact-d50557b2d7f6e31188a7001dd8b721a7-a5bfa2deac7243faa1a28b18e4f2c93e&esid=cadadd11-2a77-e911-80e8-00155d0fe673

Statins linked to higher diabetes risk | British Pharmacological Society Individuals who take cholesterol-lowering statins may be at higher risk for developing high blood sugar levels, insulin resistance, and eventually type two diabetes, according to an analysis published in the British Journal of Clinical Pharmacology.

I’ve seen lots of discussion about this headline and people wondering if they should get tested or not. The important thing to note is that the test doesn’t diagnose Alzheimer’s. What they measure is a marker of brain damage so a positive result could mean damage to other areas of the brain, not just those associated with Alzheimer’s.

Would you want to know? How about not worrying about this and taking more care of your brain now? Much better to take positive steps to reduce stress than worry and be negative. After all research shows risk of dementia can be reduced by optimal diet and lifestyle choices. It’s a no brainer!

https://m.medicalxpress.com/news/2019-01-early-alzheimer-blood.html

Blood test detects Alzheimer's damage before symptoms A simple blood test reliably detects signs of brain damage in people on the path to developing Alzheimer's disease—even before they show signs of confusion and memory loss, according to a new study from Washington University School of Medicine in St. Louis and the German Center for Neurodegenerati...

Alison Sheldrick updated their website address.

This is an interesting study. It shows that even if we have genes that increase risk of Alzheimer's disease, this risk can be reduced by following a healthy lifestyle. To find out more about what you can do to reduce risk then take a look at www.nutritionalhealthsolutions.co.uk

https://neurosciencenews.com/lifestyle-genetics-alzheimers-14480/?fbclid=IwAR0gH2yIOf_uYxiYJmw-CGw5BR8IokwKeKSw-98K4Iq-aV9Z8LnDVlwIj9Q

Healthy lifestyle may offset genetic risk of dementia - Neuroscience News Living a healthier lifestyle appears to reduce the risk of developing Alzheimer's disease in older adults with high genetic risk factors.

Dementia risk tied to these commonly prescribed drugs, study says There was nearly a 50% increased odds of dementia among adults aged 55 and older in the UK who took a strong anticholinergic medication daily for at least three years, according to a new study.

Dementia patients should be offered music and dance therapy More people with dementia should be given music or dance therapy in a bid to prevent them being "over-medicalised", the Health Secretary has said.

Blood glucose and dementia

The study below has come out just in time for dementia awareness week. It looked at HbA1c (a marker of blood glucose exposure) and rate of cognitive decline in over 5000 people for up to ten years. Simply put, the higher the HbA1c the faster the rate of cognitive decline.

You have probably heard Alzheimer’s disease being described as type three diabetes. Having diabetes tends to increase the risk of Alzheimer’s. What was interesting in this study was that cognitive decline also occurred in people who had raised HbA1c but who weren’t considered to have diabetes. So, it is important to ensure we keep our HbA1c optimal. There are a couple of other measurements we can do too - more about those next time.

https://www.ncbi.nlm.nih.gov/m/pubmed/29368156/

HbA1c, diabetes and cognitive decline: the English Longitudinal Study of Ageing. - PubMed - NCBI Diabetologia. 2018 Apr;61(4):839-848. doi: 10.1007/s00125-017-4541-7. Epub 2018 Jan 25. Research Support, Non-U.S. Gov't

Adopting a healthy lifestyle helps reduce the risk of dementia New WHO Guidelines recommend specific interventions for reducing the risk of cognitive decline and dementia

https://www.bbc.co.uk/news/health-47933345

Statins 'don't work well for one in two' Fresh research questions the merit of the cholesterol-lowering pills taken by millions of Britons.

The Selye Phenomenon: Scientists Behaving Badly Here’s a very serious question for consideration: To what degree has ego interfered with scientific progress—the identification of valid solutions to serious...