Bismuth

Bismuth subsalicylate metabolism pathway

Bismuth brands available in the market

Usual Adult Dose for Dyspepsia

524 mg orally every 30 to 60 minutes as needed not to exceed 8 doses in any 24 hour period.
Alternatively, 1048 mg to 1050 mg may be given orally every hour not to exceed 4 doses in any 24 hour period.

Comments:
-Use until diarrhea stops but not longer than 2 days.
-Bismuth subsalicylate may be useful in the prevention of traveler's diarrhea during periods of risk. The duration of use for traveler's diarrhea should not exceed approximately 3 weeks.
-Shake liquid formulations well before using.
Usual Adult Dose for Traveler's Diarrhea

524 mg orally every 30 to 60 minutes as needed not to exceed 8 doses in any 24 hour period.
Alternatively, 1048 mg to 1050 mg may be given orally every hour not to exceed 4 doses in any 24 hour period.

Comments:
-Use until diarrhea stops but not longer than 2 days.
-Bismuth subsalicylate may be useful in the prevention of traveler's diarrhea during periods of risk. The duration of use for traveler's diarrhea should not exceed approximately 3 weeks.
-Shake liquid formulations well before using.
Usual Adult Dose for Diarrhea

524 mg orally every 30 to 60 minutes as needed not to exceed 8 doses in any 24 hour period.
Alternatively, 1048 mg to 1050 mg may be given orally every hour not to exceed 4 doses in any 24 hour period.

Comments:
-Use until diarrhea stops but not longer than 2 days.
-Bismuth subsalicylate may be useful in the prevention of traveler's diarrhea during periods of risk. The duration of use for traveler's diarrhea should not exceed approximately 3 weeks.
-Shake liquid formulations well before using.
Usual Adult Dose for Helicobacter pylori Infection

524 mg orally 4 times a day.
Usual Pediatric Dose for Diarrhea

Non-specific diarrhea:

Bismuth use in ulcers caused by Helicobacter pylori.

Bismuth is a naturally occurring mineral that can act as an antacid as well as against H. pylori. Bismuth preparations are now often prescribed along with triple therapy as a component in quadruple therapy for the eradication of H. pylori. The best-known and most widely used bismuth preparation is bismuth subsalicylate (Pepto-Bismol). However, bismuth subcitrate has produced the best results against H. pylori and in the treatment of non-ulcer-related indigestion as well as peptic ulcers.