CDigital

M/S CDigital has conducted a training program focused on managing servers and applications for a real-time flow monitoring system used in data acquisition. This type of training is critical for ensuring that individuals and teams are equipped with the knowledge and skills necessary to effectively manage the system and ensure it is running smoothly.

With the rapid pace of technological advancement and the increasing importance of data acquisition in many industries, it's essential to have well-trained professionals who can manage these systems effectively. By conducting training programs like this, M/S CDigital is helping to ensure that there are skilled individuals who can manage and maintain these systems to maximize their value and benefit to organizations.

National Institutes of Health researchers have developed and released an innovative software tool to assemble truly complete (i.e., gapless) genome sequences from a variety of species. This software, called Verkko, which means "network" in Finnish, makes the process of assembling complete genome sequences more affordable and accessible.

Software assembles complete genome sequences on-demand: Software opens the door for a greater number of complete genome sequences Researchers have developed and released an innovative software tool to assemble truly complete (i.e., gapless) genome sequences from a variety of species.

A controlled trial of an international team of researchers led by the Butler Columbia Aging Center at the Columbia University Mailman School of Public Health shows that caloric restriction can slow the pace of aging in healthy adults. The CALERIE™ intervention slowed the pace of aging measured from participants’ blood DNA methylation using the algorithm DunedinPACE (Pace of Aging, Computed from the Epigenome). The intervention effect on DunedinPACE represented a 2-3 percent slowing in the pace of aging, which in other studies translates to a 10-15 percent reduction in mortality risk, an effect similar to a smoking cessation intervention.

Calorie restriction slows pace of aging in healthy adults In a first of its kind randomized controlled trial an international team of researchers shows that caloric restriction can slow the pace of aging in healthy adults. The CALERIE™ intervention slowed pace of aging measured from participants' blood DNA methylation using the algorithm DunedinPACE (Pac...

, Awan Distribution, and Huawei conducted a successful event at Pearl-Continental Hotel Muzaffarabad! "Power your IT infrastructure" The Event was a platform to discuss the crucial role of modern digital ecosystems in driving progress and innovation. The Senior Most Minister for LG&RDD Khawaja Farooq Ahmed was Chief Guest.
Madam Midhat Shehzad Secretory Tourism AJ&K, Mr. Mansoor Qadir Dar The Secretory Food AJ&K, Dr.Khalid Rafique DG IT Board AJ&K, Sardar Asim Khan Director of Technical ITBoard, Malik Ijaz the Director of IT Electricity Department AJ&K, Sardar Idrees Director IT Finance Dett, AJ&K along with other senior officials of the govt of AJ&K attended the event. Mr. Muhammad Ahsan Bashir the Managing Director CDigital shared its journey in AJ&K and emphasized the significance of IT in the region's growth and development.
Huawei Launched its new product “Idea Hub S2 series” in AJ&K.
All the participants appreciated the efforts of CDigital for conducting such a beautiful and valuable event for the people of Kashmir.
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What a day! We had an amazing time during our sports activities day on Saturday at . Our staff played cricket, football, and badminton, and had a blast competing against each other. But the real highlight of the day was the orange party, where we all came together to enjoy some delicious orange treats and celebrate our team spirit. Thanks to everyone who participated and made this event a huge success! Special thanks to our admin who arrange this event successfully. Check out some of the pictures from the day!

The Electricity Department of AJ&K team visits our Office to check the progress of the CERP project. CDigital team briefing them on the project.

Researchers have discovered how to modify the function of an enzyme crucial to fat production in fruit flies, which could lead to more effective treatments of cancer and childhood obesity in humans.

Discovery of metabolic switch could lead to targeted treatment of obesity, cancer Researchers have discovered how to modify the function of an enzyme crucial to fat production in fruit flies, which could lead to more effective treatments of cancer and childhood obesity in humans.

"For people with drug-resistant epilepsy, or those who have been unable to find effective treatment to reduce seizures, it's encouraging to see that there are lifestyle changes that can be combined with standard drug therapy to reduce the number of seizures"
Following a modified Atkins diet high in fat and low in carbohydrates plus taking medication may reduce seizures in people with tough-to-treat epilepsy

Can diet combined with drugs reduce seizures? Following a modified Atkins diet high in fat and low in carbohydrates plus taking medication may reduce seizures in people with tough-to-treat epilepsy, according to a new study.

A fundamental challenge in drug development is the balance between optimizing a drug's lock-and-key fit with its target and the drug's ability to make its way across the cellular membrane and access that target. The search for cell-permeable drugs has conventionally focused on low-molecular weight molecules with rigid, nonpolar chemical structures. However, emerging therapeutic strategies break traditional drug design rules by employing larger, flexibly linked chemical entities.

New pathway for molecular cancer drug therapies: Bitopic inhibitors may lay foundation for new approach to disease treatment Researchers reveal the discovery of a cellular uptake pathway important for larger molecules. These large and complex molecules bind in unconventional ways to their targets, are efficiently taken up by target cells, and can be harnessed to create new drugs for the treatment of cancer and other disea...

Happy New Year from the team at CDigital! We hope the new year brings you and your loved ones health, happiness, and success. Here's to a fantastic year ahead!

Lung cancer is the deadliest cancer in the United States and around the world. Many of the currently available therapies have been ineffective, leaving patients with very few options. A promising new strategy to treat cancer has been bacterial therapy, but while this treatment modality has quickly progressed from laboratory experiments to clinical trials in the last five years, the most effective treatment for certain types of cancers may be in combination with other drugs.

New bacterial therapy approach to treat lung cancer: Columbia biomedical engineers develop therapeutic strategy to combine bacterial therapies with pharmaceutical drugs Researchers report that they have developed a new experimental pipeline to combine bacterial therapy with current cancer drugs. Their study, which explores resistance to bacterial therapy at the molecular level, has achieved better treatment efficacy without additional toxicity in laboratory models.

Researchers have discovered an antibody with the potential to protect against Strep A infection, as well as a rare form of antibody binding, that leads to an effective immune response against bacteria. The discovery could explain why so many Group A strep vaccines have failed.
One strategy that the scientific community uses to find new ways of fighting bacterial infections is to create target-seeking antibodies. First, the antibodies that the body's immune system produces in the event of infection are mapped, and then their effect on the immune system is studied. In this way, antibodies can be identified that can be used both for preventive treatment and for treatment during an ongoing infection.

Antibody discovery paves way for new therapies against group A streptococcal infections Researchers have discovered an antibody with the potential to protect against Strep A infection, as well as a rare form of antibody binding, that leads to an effective immune response against bacteria. The discovery could explain why so many Group A strep vaccines have failed.

Researchers at the University of Copenhagen's Faculty of Science have modified a yeast cell to sense the active substances in cannabis and get it to turn red when it does. The researchers substituted the yeast cell's with a sense of taste and smell that allows them to detect cannabinoids, the active substances in cannabis. Going one step further, the researchers made the yeast turn red or glow when it successfully detects cannabinoids.

Scientists modify yeast cell and turn it into a cannabis tracker Researchers have modified a yeast cell to sense the active substances in cannabis and get it to turn red when it does. The result paves the way for more actors to discover new medicinal substances and for a new type of drug test that can be done with a smartphone.

Early life experiences can impact the activity of our genes much later on and even affect longevity. The scientists report that gene expression 'memory' can persist across the lifespan, and may present a novel target for improving late-life health.

Early life experiences can have long-lasting impact on genes Early life experiences can impact the activity of our genes much later on and even affect longevity, finds a new study in fruit flies.

Little is known about how social behavior develops in the earliest stages of life. But most animals including humans are born with an innate ability to interact socially or form bonds with others. And that contributes to success throughout life.

Now, a new animal study points to a gene that is important for the earliest development of basic social behaviors. The work also suggests that exposure to certain drugs and environmental risk factors during embryonic development can cause changes to this gene, leading to alterations in social behavior that are similar to those found in individuals who have autism. Much to their surprise, the researchers also found they could reverse some of the effects using an experimental drug.

Gene that guides earliest social behaviors could be key to understanding autism A new animal study points to a gene that is important for the earliest development of basic social behaviors. The work also suggests that exposure to certain drugs and environmental risk factors during embryonic development can cause changes to this gene, leading to alterations in social behavior th...

Researchers found that the fungus removes mercury from the soil around plant roots, and from fresh and saltwater. The researchers also genetically engineered the fungus to amplify its mercury detoxifying effects. This new work suggests Metarhizium could provide an inexpensive and efficient way to protect crops grown in polluted areas and remediate mercury-laden waterways.

How a common fungus eliminates toxic mercury from soil and water Researchers found that the fungus Metarhizium robertsii removes mercury from the soil around plant roots, and from fresh and saltwater. The researchers also genetically engineered the fungus to amplify its mercury detoxifying effects. This new work suggests Metarhizium could provide an inexpensive a...

Scientists have successfully bioengineered an important protein in plants to increase the yield of oil from their fruits and seeds -- a holy grail for the global agri-food industry. Their patent-pending method can increase oil content in seeds by 15 to 18 percent, which is a significant improvement since major oil-producing crops such as soybean, sunflower, rapeseed, and peanut, already have a high percentage of oil in their seeds. This innovation can help the world in its quest for sustainability, helping to reduce the amount of arable land needed for oil-yielding crops while increasing the yield to meet the world's growing demand for vegetable oil.

Scientists genetically engineer plants to yield more vegetable oil Scientists have successfully bioengineered an important protein in plants to increase the yield of oil from their fruits and seeds -- a holy grail for the global agri-food industry. Their patent-pending method can increase oil content in seeds by 15 to 18 per cent, which is a significant improvement...

The unreasonable use of antibiotics has pushed bacteria to develop resistance mechanisms to this type of treatment. This phenomenon, known as antibiotic resistance, is now considered by the WHO as one of the greatest threats to health. The lack of treatment against multi-resistant bacteria could bring us back to a time when millions of people died of pneumonia or salmonella.

https://www.sciencedaily.com/releases/2022/11/221104113518.htm

Researchers have succeeded in identifying a new approach for the therapy of colorectal cancer. In preclinical models and studies on human immune cells, they found that urolithin A, a metabolite product from pomegranate, sustainably improves the function of immune cells in their fight against cancer. After treatment with urolithin A, tumour-fighting immune cells become T memory stem cells which, due to their ability to divide, constantly supply the immune system with rejuvenated, non-exhausted T cells.

Metabolite product from pomegranate: Researchers identify way to boost tumor-fighting immune cells: Preclinical models and cell culture experiments show 'rejuvenation' of T cells by urolithin A -- clinical trials planned Researchers have succeeded in identifying a new approach for the therapy of colorectal cancer. In preclinical models and studies on human immune cells, they found that urolithin A, a metabolite product from pomegranate, sustainably improves the function of immune cells in their fight against cancer....

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Scientists have found that a stress response in cells, when 'switched on' at a post-reproductive age, could be the key to slowing down ageing and promote longevity.

Manipulating stress response in cells could help slow down aging: Findings from lab studies on roundworms could open the door to therapies for age-related disorders Scientists have found that a stress response in cells, when 'switched on' at a post-reproductive age, could be the key to slow down ageing and promote longevity.

The candidates are required to meet the eligibility criteria and only shortlisted candidates will be called for interview. These positions lead to a permanent employment based on performance. Email your latest resume at [email protected] . For detailed job description of the post, please visit our website
QuratulAin Malik < >
Note: - Last Date to Apply: 15-November-2022

We are looking forward to engage graduates/experienced professionals for our IT Division, for the following positions

Experiments in cell cultures and mice showed that blocking the function of a specific enzyme present in all cells triggers a powerful innate immune response, the body's first line of defense against any foreign invader. When challenged by several types of viruses in the study, this response dramatically lowered the replication of viral particles and protected mouse lungs from damage.

A potential target for developing broad-spectrum antiviral therapies: Study finds inhibiting enzyme boosts the innate immune response Researchers have identified a promising strategy for development of broad-spectrum antiviral therapies that centers around promoting a strong immune response capable of stopping a number of viruses in their infectious tracks.

Yeast cells and human immune system cells rely on surprisingly similar chemical reactions to know when to grow. University of Arizona scientists have identified subtle differences between the two cell types that could help spur the development of antifungal drugs that are able to attack disease-causing yeasts in the body while sparing the immune system.

Newly discovered protein could be used to produce life-saving antifungals Researchers have discovered a protein that is responsible for controlling cell growth in yeasts. Since humans and yeasts have remarkably similar cellular mechanisms, teasing out the differences presents drug developers with new targets for treatments.