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What is human growth hormone?

The body naturally produces growth hormone (HGH or simply GH) in the pituitary gland, and, as its name implies, it is responsible for cell growth and regeneration. Increasing muscle mass and bone density are impossible without GH, but it also plays a major role in maintaining the health of all human tissue, including that of the brain and other vital organs. When secreted, GH remains active in the bloodstream for only a few minutes, but this is enough time for the liver to convert it into growth factors, the most crucial of which is insulin-like growth factor-1, or IGF-1, which boasts a host of anabolic properties. Scientists began to harvest GH from the pituitary glands of cadavers in the 1950s, but didn’t synthesize the first HGH in laboratories until 1981, with its use as a performance-enhancing drug becoming popular shortly thereafter

Proviron (Mesterolone)

Proviron History and Overview
Proviron is the trade / brand name for the androgen known as Mesterolone. It is an oral product, and is not considered an anabolic steroid. This is because its anabolic activity is known for being extremely weak – so weak, in fact, that it can be practically considered nonexistent. Proviron was initially developed by Schering in 1934, making it one of the oldest steroids manufactured and marketed for medical use. Mesterolone is so old, in fact, that it shared its inception alongside Methyltestosterone in 1935, and Testosterone Propionate in 1937, which were two of the first anabolic steroids put to use in medicine as well. Of course, Methyltestosterone and Testosterone Propionate are best remembered for all of their glory while Proviron is/was lesser known. This is likely due to the fact that the former two anabolic steroids were demonstrated as being very strong anabolic agents, while the latter was not.
Although Proviron is considered a very old medication, it still stands the test of time as being known as a compound that has impressive effectiveness as a medicine alongside an impressive history of safety and tolerance among patients. Within the medical establishment, Proviron has been utilized as a medication for the treatment of declining well-being in older males due to declining androgen levels, libido dysfunction in males, and infertility.
Its use as a fertility aid is where Proviron was really emphasized in medical literature. This is because while almost all anabolic/androgenic steroids are known to cause temporary infertility, Proviron in normal therapeutic dosages actually barely suppresses endogenous gonadotropins (LH and FSH) when utilized. However, Proviron is poorly misunderstood as a compound that increases LH, which it does not do. Instead, research has demonstrated that Proviron provides the androgenic effects necessary for spermatogenesis in specific areas in the te**es.

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Schering still manufactures Mesterolone under the name of Proviron across the world today. It has been sold under different brand names as well, including Pluriviron (in Germany by Asche), Vistimon (in Germany by Jenepharm), and Restore (in India, by Brown and Burke). What is interesting, however, is that Proviron was never approved for use on the prescription market in the United States.
Proviron Chemical Characteristics
Proviron is a modified derivative of dihydrotestosterone (DHT) via the addition of a methyl group on its first carbon (1-methyl dihydrotestosterone). As previously mentioned, it is an extremely weak anabolic, which is why Proviron is almost always referred to as an androgen (or androgenic steroid). Studies have demonstrated the reason for its weak anabolic effects: it shares with its parent compound (DHT) a similar property – it is rapidly metabolized and broken down into inactive metabolites once it enters into muscle tissue.

This has always been the problem with dihydrotestosterone itself – once it enters muscle tissue, the enzyme 3-hydroxysteroid dehydrogenase (where it is in very high concentration in muscle tissue) binds to it, and renders it inactive by converting it into a compound that has no anabolic effects. This is the real reason for Proviron’s weak anabolic effects. There have been false rumors about Proviron’s weak anabolic nature in circulation among bodybuilding communities that Proviron “blocks the androgen receptor in muscle tissue”, which is wrong, and this rumor should therefore be put to rest.
An added benefit of Proviron is its ability to have a high affinity for SHBG (S*x Hormone Binding Globulin), which is a protein that binds to anabolic steroids in the bloodstream (namely, Testosterone) and renders them completely inactive once bound. The use of Proviron in this case alongside other anabolic steroids may magnify the activity and effects of other anabolic steroids through this pathway, leaving more unbound and free Testosterone to perform its job.
A well-known benefit of Proviron is also its ability to act as an anti-estrogen via its activity as an aromatase inhibitor. It should be noted, however, that its activity as an aromatase inhibitor is not regarded as strong as Aromasin, Arimidex, or Letrozole, but it still works and can be used as such. Its strength as an aromatase inhibitor can be compared to Arimidex, but slightly lower in terms of strength.
Proviron Side Effects
Because Proviron is a DHT-derivative, it carries with it no risks at any dosage for estrogenic side effects. In fact, as previously mentioned, Proviron acts as an anti-estrogen via its activity as an aromatase inhibitor in the body. This can result in the mitigation of estrogenic side effects from other compounds via the reduction of total circulating plasma levels of Estrogen. Research has demonstrated that because of this effect of Proviron, it has been utilized medically in the treatment of gynecomastia and breast cancers because of its strong androgenic nature combined with its anti-estrogenic capabilities.

Arimidex vs. Aromasin - which to use on cycle?

When using anabolic steroids to add bulk, to improve your performance, or even to maintain muscle mass while you melt away unwanted fat, it is vital to understand how that steroid works and whether it converts to estrogen in your body. The vast majority of steroids do require treatment with an aromatase inhibitor like Aromasin or Arimidex. Here, we will look at Aromasin vs. Arimidex and which is the better choice during a steroid cycle.

First Things First – What Is an Aromatase Inhibitor?

When looking at Aromasin vs. Arimidex, it’s important to remember that both compounds are aromatase inhibitors. In the bodybuilding and athletic circles, they’re often called anti-estrogens. Both products work by blocking an enzyme known as aromatase that converts excess free testosterone (and testosterone-derived steroids) into estrogen. When using steroids, some of them will aromatize thanks to the presence of that enzyme. While some estrogen is healthy and even required, even in men, too much can cause unwanted side effects like bloating, mood swings, and even gynecomastia. Aromasin and Arimidex are vital parts of your steroid cycles because they stop aromatization.

Things to Consider when Buying Aromatase Inhibitors

Aromasin vs. Arimidex When looking at Aromasin vs. Arimidex on-cycle, there are a few factors to keep in mind. Of these, one of the most important for bodybuilders and athletes is availability. In some cases, it is much simpler to find one product over the other, making it more convenient. What’s more, you will also need to consider things like the overall price and what kinds of side effects the compound can produce. Some drugs can worsen your lipid profile or cause unwanted effects, and others may not be cost-effective.

Of course, while all of the above are important considerations, you should also be concerned with the action of the anti-estrogen you choose. In short, how well does it work, and will it prevent the buildup of estrogen and irreversible side effects like gynecomastia? Fortunately, this is where the Aromasin vs. Arimidex debate ends – both are equally capable of preventing estrogenic side effects. With that in mind, your decision will come down to research and what you have available.

All About Aromasin

Aromasin is the brand name given to a drug called exemestane, and it was first developed to treat breast cancer in women. Some certain types of cancers grow more quickly when exposed to a healthy supply of estrogen, so by blocking the creation of estrogen in the first place, it is possible to slow the growth of cancerous breast cancer tumors, making treatments like chemotherapy and radiation more successful in the long run.

Aromasin Benefits

Aromasin is a better choice among men who may be concerned about their lipid profiles. Many anabolic steroids come with high cholesterol warnings, so many men are very particular about the supplements they use alongside those steroids. Aromasin is a better option when it comes to managing cholesterol and keeping lipid profiles in check.
Aromasin is a suicidal inhibitor. This means that once it bonds to the molecules of the aromatase enzyme, it doesn’t break free. It remains attached for the entire lifecycle of the enzyme. This means there’s less estrogen rebound. Remember, though, that you need some estrogen in your body, and just as steroids can shut down your body’s natural testosterone production, Aromasin can shut down your body’s estrogen production through that suicidal inhibition.

Aromasin Downfalls

When examining Arimidex vs. Aromasin, most people agree that Aromasin is the better choice. However, this makes it the costlier choice, especially on the street. Aromasin may cost anywhere from two to three times as much as Arimidex, even though both accomplish the same goals.
Some men have reported that Aromasin has caused “shedding”. This term refers to unwanted hair loss, including hair on the head and hair on the body.
Aromasin can cause side effects that mimic those experienced by menopausal women, even in men. This may include things like hot flashes, mood swings, and more.
It takes up to a week for Aromasin to truly start blocking aromatase.
All About Arimidex
Arimidex, on the other hand, is the brand name given to an anti-estrogen compound called anastrozole. Like Aromasin, it was originally developed to help in the fight against breast cancer by reducing estrogen, thereby slowing or even reversing the growth of cancerous tumors. Over time, it also became popular among bodybuilders and athletes interested in protecting themselves against the unwanted side effects associated with anabolic steroids.

Arimidex Benefits

Arimidex is much more affordable than Aromasin, and in some places, it costs half to a third the price of its more expensive counterpart.
Arimidex is widely available online and on the street, making it far more attainable than Aromasin.
Unlike Aromasin, reports of hair loss while using Arimidex to prevent or counteract estrogenic side effects are very rare.
The side effects associated with Arimidex vs. Aromasin are roughly the same, but most men agree that Arimidex is far more tolerable.
Arimidex goes to work in the first couple of days rather than taking a week or more to fully protect against estrogenic side effects.

Arimidex Downfalls

Though it is easier to find, Arimidex may further worsen lipid profiles. When considering Aromasin vs. Arimidex, be sure to consider your personal health. If you have high cholesterol, or if you are using a steroid known to cause high cholesterol, then consider taking Aromasin, instead.
While Arimidex does go to work more quickly, it is less forgiving. Men must be diligent about their dosing, taking it at least every other day, in order to fully protect themselves. Missing even one dose could lead to unwanted sides.
In the great debate over Aromasin vs. Arimidex, the truth is that either one will get the job done. Each one of these compounds has its own unique set of benefits and downfalls, and it is up to the individual user to decide what’s right for his or her needs. Remember, too, that genetics can play a role in your body’s response, so what works for most people may not work for you.

Warning! Articles related to the use of illegal performance enhancing drugs are for information purposes only and are the sole expressions of the individual authors opinion. We do not promote the use of these substances and the information contained within this publication is not intended to persuade or encourage the use or possession of illegal substances. These substances should be used only under the advice and supervision of a qualified, licensed physician.

Cardarine (GW 501516)

Cardarine (GW-501516) is drug that binds to the PPAR receptor. It was first created by Glaxo Smith Kline and Ligand Pharmaceuticals in 1992. It was discovered that Cardarine, when binding to the PPAR receptor, recruits what is called the coactivator PGC-1α enzyme, which then increases the expression of genes involved in the expenditure of energy. Rats treated with Cardarine were shown to have increased fatty acid metabolism and increased protection against obesity from eating a bad diet, as well as an increased protection from type-2 diabetes. In another study on Rhesus monkeys, cardarine was shown to increase HDL (good cholesterol) and decrease LDL (bad cholesterol). Reasons for this effect appeared to be caused by an increased expression of the cholesterol transporter ABCA1. In other words, cardarine activates the same genetic pathways that are involved in exercise. In addition, cardarine was studied for use in treating cardio disease before its development was halted in 2007.

What is Cardarine Used for?

Cardarine is great for pretty much everything! Incredible endurance benefits from it are probably the most prominent reason to use this product. Not only has it proven to increase endurance in scientific studies, but when you use it for yourself you'd see that the results are nothing short of amazing!

Some of the other benefits include:

Rapidly melts fat and NON catabolic.
Provides noticeable results on the first dose.
The ability to run for as long as 8-12+ weeks.
Is versatile and can be stacked with anything.
Can be used while cutting OR bulking.
No side effects, liver toxicity, or suppression have been reported.
No need for a PCT

Cardarine can be stacked with pretty much anything, and it will enhance the results of the cycle. For anabolic-androgenic steroid users who like the drug trenbolone, cardarine is fantastic at combating the negative side effects of “tren” and even enhancing the positive effects.

Testosterone - King of steroids
Testosterone is not only the most popular steroid in bodybuilding. Testosterone replacement therapy (TRT) is also indispensable.

Testosterone Cypionate vs. Testosterone Enanthate: Which is Right for You?

Understanding Testosterone Cypionate and Testosterone Enanthate

When it comes to optimizing men’s health and vitality, testosterone plays a crucial role. Testosterone replacement therapy (TRT) has gained popularity among men who are looking to restore their testosterone levels and enhance their overall well-being. Two commonly prescribed forms of testosterone for TRT are testosterone cypionate and testosterone enanthate.

Testosterone Cypionate: This injectable hormone medication is typically administered through an intramuscular injection. Testosterone cypionate has a longer half-life, which means it remains active in the body for a longer duration compared to other testosterone esters. Doctors usually recommend injections of testosterone cypionate once every 7–10 days, providing a steady release of testosterone into the bloodstream.

Testosterone Enanthate: Similar to testosterone cypionate, testosterone enanthate is also an injectable hormone medication used in TRT. It has a slightly shorter half-life than cypionate but remains active for a considerable period. Typically, testosterone enanthate injections are administered once every 5–7 days, ensuring a consistent supply of testosterone in the body.
Benefits of Testosterone Cypionate and Testosterone Enanthate
1. Increased Energy and Vitality

One of the primary benefits of testosterone cypionate and testosterone enanthate is the potential for increased energy levels and vitality. Men experiencing low testosterone often report feelings of fatigue, low motivation, and reduced stamina. By restoring testosterone levels to a healthy range, these forms of testosterone can help combat these symptoms, leading to improved energy levels and an overall sense of well-being.
2. Enhanced Muscle Strength and Mass

Testosterone is crucial for muscle development and maintenance in men. Both testosterone cypionate and testosterone enanthate can help promote muscle growth and increase muscle strength. By stimulating protein synthesis and enhancing nitrogen retention, these testosterone forms aid in the formation of lean muscle mass. Regular exercise and strength training, combined with TRT using testosterone cypionate or testosterone enanthate, can yield significant improvements in muscle strength and size.
3. Improved Mood and Cognitive Function

Testosterone influences mood and cognitive function in men. Low testosterone levels can lead to feelings of irritability, depression, and difficulty concentrating. Testosterone cypionate and testosterone enanthate have been shown to improve mood, reduce depressive symptoms, and enhance cognitive abilities, including memory and focus. Restoring testosterone levels through TRT can have a positive impact on mental well-being and overall cognitive performance.
4. Increased Libido and S*xual Function

Testosterone is closely linked to male sexual health and function. Low testosterone levels can cause decreased libido, erectile dysfunction, and other sexual problems. Testosterone cypionate and testosterone enanthate can help improve libido, enhance sexual desire, and address issues related to sexual function. By optimizing testosterone levels, these forms of testosterone can potentially reignite sexual vitality and improve overall sexual satisfaction.
5. Overall Well-being and Quality of Life

By addressing the symptoms associated with low testosterone levels, such as fatigue, muscle weakness, mood disturbances, and sexual dysfunction, testosterone cypionate and testosterone enanthate can contribute to an improved quality of life. Many men who undergo TRT with these testosterone forms report an overall sense of well-being, increased confidence, and a higher quality of life.
Differences Between Testosterone Cypionate and Testosterone Enanthate

While both testosterone cypionate and testosterone enanthate offer remarkable benefits, it’s important to understand their unique characteristics:

Dosage Frequency: Testosterone cypionate injections are typically administered every 7–10 days, while testosterone enanthate injections are given every 5–7 days. Consider your lifestyle and preference for convenience when choosing the best fit for your routine.
Half-Life: Testosterone cypionate boasts a longer half-life compared to testosterone enanthate. This means fewer injections are required, providing a more convenient treatment option. Testosterone enanthate, though slightly shorter in half-life, still maintains consistent testosterone levels.
Side Effects: Testosterone therapy, including the use of Testosterone Cypionate and Testosterone Enanthate, may have potential side effects such as acne, fluid retention, and increases in red blood cell count.
Consistent Testosterone Levels: Both forms of testosterone provide consistent levels of testosterone in the body when administered as prescribed.
Individual Response: Each person responds differently to medications. While the benefits of both testosterone cypionate and testosterone enanthate are similar, your unique physiology may favor one over the other.

Conclusion

If you’re a man seeking to enhance your well-being and address symptoms associated with low testosterone, both testosterone cypionate and testosterone enanthate can be valuable treatment options. They offer similar benefits in terms of energy, muscle strength, mood, and sexual function. However, their differences in dosage frequency and half-life should be considered in consultation with a healthcare professional to determine the most suitable choice for your needs. Remember, the goal is to optimize your testosterone levels and improve your overall quality of life.

Milo-Lab has now its own Human Growth Hormones (HGH).

Benefits of HGH:
If you have an actual growth hormone deficiency, supplementation can improve your quality of life.

While not all of these benefits are true for every person, it’s wise to speak to a healthcare professional to help you to achieve the results you’re hoping for. A good doctor should be able to set realistic expectations about what you can achieve.

Results are unlikely to happen overnight, but with HGH treatment taken over time, you can hope to achieve some of the following benefits:

• Improved mood and mental health

• Improved energy levels

• Better quality of sleep

• Increased muscle mass and strength

• Ability to lose weight and keep it off if used alongside a healthy diet

• Increased libido and sexual performance

• Lower cholesterol

• Balanced testosterone levels

• Better mental acuity and memory

• Improved bone mass

• Better immune system function

• Replenished and rejuvenated skin

• Faster recovery from injuries and wounds.

Our satisfied customer on the stage!
We support professional bodybuilders as well as hobby bodybuilders and men who would like to do testosterone replacement therapy. Feel free to contact us!

"Satisfied customer 👍"
This customer sent us yesterday his picture with this words. He is 44 years old, 176cm and 83kg. He has a really great body! Of course he had to train hard to get this body. But we support him with our gear. You too can look like this with the right support. Feel free to get in touch with us!

WHAT IS MK-677 (IBUTAMOREN)?

MK-677 (also known as ibutamoren), promotes the secretion of the growth hormone (GH) and increases insulin-like growth factor 1 (IGF-1). Ibutamoren increases growth hormone levels by mimicking the action of the hormone ghrelin and binding to one of the ghrelin receptors (GHSR) in the brain.

Activated GHSR stimulates growth hormone release from the brain. Clinical studies describe only the effects ibutamoren has on appetite and as expected, like ghrelin, ibutamoren increases it. GHSR is found in brain regions that control appetite, pleasure, mood, biological rhythms, memory, and cognition.

Therefore, we can expect that ibutamoren may also affect these functions. It increases growth hormone levels with little or no increase in other hormones, such as cortisol. Cortisol suppresses the immune system, reduces wound healing, and impairs learning and memory, and it’s usually not good to have this hormone elevated.
MK-677 Benefits and Results

The benefits of MK-677 include muscle-building, a reduction in muscle wasting, better bone density, improved sleep, and anti-aging properties. It may also have nootropic effects and it can be beneficial in treating growth hormone deficiencies. Read on for a more in-depth look at these benefits.
Helps Build Muscles

Ibutamoren is frequently used as an anabolic substance, to increase lean body mass. It is orally active and can be taken once a day. MK-677 stimulates Growth Hormone and IGF-1 which each factor in significantly to maintaining lean body mass. Growth Hormone is believed by many to stimulate an increase in muscle size and strength and the ability of MK-677 to increase Growth Hormone production make it a popular choice.

One study that studied 60-year-olds indicated that injections to stimulate Growth Hormones led to increased strength in thigh muscles. When it comes to MK-677 stimulating muscle growth, its results will vary by person depending on their exercise regimen and if they have any health conditions.

In another study of 24 obese men, a two-month treatment with ibutamoren increased lean mass, and transiently increased basal metabolic rate (BMR)

Reduces Muscle Wasting

MK-677 has shown in recent studies to alleviate muscle wasting that can be caused by a decline in protein within an individual’s diet. In one study a group of healthy young adults were tested to determine if MK-677 could reverse protein catabolism and the results proved to be quite positive. As a result, MK-677 is theorized to be possibly being an effective treatment for individuals who suffer from catabolic conditions.

Increases Bone Density

Several studies have indicated that long-term use of MK-677 can have tremendous results to increase bone mineral density. This finding can benefit several populations including obese individuals, older adults, and women with menopause. These distinct populations can have detrimental health problems due to low bone mineral density and MK-677 has proven to be an effective treatment for many of them.

In 24 healthy obese male volunteers, ibutamoren increased bone turnover.

In 187 elderly adults (65 years or older), ibutamoren increased bone building, as measured by osteocalcin, a marker of bone turnover in multiple studies.

In one study with 292 post-menopausal women, ibutamoren increased bone mineral density, which helps increase bone strength and prevent osteoporosis.

The groups of people who serve to benefit by MK-677’s ability to increase bone density must research the possibility of any long-term side effects since increases in bone density typically take more than a year’s use.
Improves Sleep

Since Growth Hormone is known to help improve sleep quality, it is commonly thought that Ibutamoren Mesylate can assist with sleep quality since it stimulates production in Growth Hormone.

A study showed that in both younger and elderly subjects, ibutamoren improved sleep quality and REM (rapid eye movement) sleep duration.

Apart from scientific studies, there have been many reports of subjective improvements in sleep quality.
Combats Aging and May Increase Longevity

As seen with other hormones in the body, Growth Hormone naturally begins a steady decline once a certain age is hit. Individuals who are aging can benefit from taking MK 677 since Growth Hormone and IGF-1 will be increased in the body among its consumption. Aging individuals who take MK 677 can improve their overall hormone profiles as they give their declining GH levels (Growth Hormone levels) a boost.

In a study with 65 elderly men and women, daily ibutamoren increased GH and IGF-1 levels to those of healthy young adults without serious adverse effects.

In another study with 24 obese males, ibutamoren rejuvenated the growth hormone profile.
May Have Nootropic Effects

Since MK-677 shares a lot of similar qualities to Ghrelin and binds to its receptors, it is believed that MK 677 can have the same effects on the brain that Ghrelin has.

However, there are no studies that confirm whether or not MK 677 has direct nootropic effects on the brain. Scientists do have hope though that a couple of noticeable indirect methods may explain how MK 677 can be of assistance to cognitive function. Looking back at the previous section, one method that shows promise is Ibutamoren’s ability to improve sleep quality by increasing REM sleep.

Obtaining the proper amount of sleep each night is extremely important when trying to achieve adequate cognitive function. MK-677 can improve cognitive function by assisting individuals with the ability to get a good night’s rest. The ability of MK-677 to stimulate IGF-1 production can also indirectly improve cognitive function based on IGF-1’s role in cognitive function. One study indicated that IGF-1 positively affected participants’ ability to perform well on cognitive tests. We know that sleep is essential for good cognitive function.
Beneficial in Treating Growth Hormone Deficiency

Ibutamoren can increase growth hormone, IGF-1, and IGFBP-3 levels in children with growth hormone deficiency. Furthermore, these effects are achieved without changing the concentrations of prolactin, glucose, triiodothyronine (T3), thyroxine (T4), thyrotropin, cortisol or insulin.

In severely GH-deficient men, ibutamoren increased IGF-1 and growth hormone, with no significant changes in cortisol, PRL, and thyroid hormone levels. However, insulin and glucose were increased.
Potential Side Effects of MK-677

MK 677 has not produced very many side effects for its users to be concerned about, but certain populations may have some side effects to look out for.

Individuals who are vulnerable to insulin sensitivity or who have Diabetes may be at risk when taking MK-677. Symptoms associated with these conditions could possibly be exacerbated by the use of MK 677. As with any other compound, correct dosing and usage of MK-677 is the key. In studies that looked at how MK-677 increases muscle mass, the dosage was key. Side effects of MK-677 are usually the result of a handful of two things: improper dosage and extended use.

Reported side effects of MK-677 are typically the result of unnaturally high levels of growth hormone in the body from taking too much too often, which include:

Increased appetite
Lethargy
Joint pain if you have previous medical conditions or elevated hormone levels
Insulin resistance
Possible increase in prolactin levels, which can be controlled

When dosed properly, the side effects of MK-677 are minimal to none compared to the results you get from taking it properly.

Conclusion

MK-677 has shown to provide numerous health benefits for individuals with certain conditions. Those with low bone density, those who have trouble sleeping at night, and individuals with catabolic conditions can all benefit greatly from the use of MK 677.

The ability of the MK 677 secretagogue to effectively secrete Growth Hormone and IGF-1 proves to be a useful tool for many different populations. MK 677 has shown through numerous studies to benefit the elderly, those with obesity, have problems sleeping, have low bone density, and others. For these populations, MK 677 can be used as a helpful tool to combat issues that can be caused in large part due to a lack of Growth Hormone and IGF-1.