Organicell

Organicell Starts Enrolling Trial

Organicell Starts Enrolling Long COVID Trial - Organicell MIAMI, FL / ACCESSWIRE / November 17, 2022 / Organicell Regenerative Medicine, Inc. (OTCQB: OCEL), a clinical-stage biopharmaceutical company

Organicell announces Mayo Clinic in Phoenix, Arizona will be the clinical trial site for their Phase I/II Randomized, Double Blinded, Placebo Trial to Evaluate the Safety and Potential Efficacy of Intravenous Infusion of Zofin for the Treatment of Chronic Obstructive Pulmonary Disease (COPD).

Organicell Activates COPD Trial at Mayo Clinic - Organicell DAVIE, FL / ACCESSWIRE / November 15, 2022 / Organicell Regenerative Medicine, Inc. (OTCQB:OCEL), a clinical-stage biopharmaceutical company focused

Organicell Announces Additions to Board of Directors

Expanded Board of Director Broadens Company’s Access to Valued Business Expertise and Relationships

Organicell Regenerative Medicine, Inc. Announces Additions to Board of Directors - Organicell Expanded Board of Director Broadens Company's Access to Valued Business Expertise and Relationships

Organicell Announces Expansion of Management Team, recruiting a new Chief Operating Officer, Chief Information Officer, and Director of Finance.

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Organicell Regenerative Medicine, Inc. Announces Expansion of Management Team - Organicell MIAMI, FL / ACCESSWIRE / September 20, 2022 / Organicell Regenerative Medicine, Inc. (OTCQB:OCEL), a clinical-stage biopharmaceutical company focused on

Organicell Regenerative Medicine, Inc. Announces Expansion into Health and Beauty Market

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Organicell Regenerative Medicine, Inc. Announces Expansion into Health and Beauty Market - Organicell MIAMI, FL / ACCESSWIRE / September 16, 2022 / Organicell Regenerative Medicine, Inc. (OTCQB:OCEL), a clinical-stage biopharmaceutical company focused on

BeautyHealth’s Hydrafacial Announces Partnership with Organicell to Develop Breakthrough Exosome Booster to Address Aging and Inflammation through Regenerative Technology.

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BeautyHealth’s Hydrafacial Announces Partnership with Organicell to Develop Breakthrough Exosome Booster - Organicell Co-Created with Organicell, the first-to-market booster will address aging and inflammation through regenerative technology

Organicell Regenerative Medicine, Inc. Secures Additional $11 Million in Financing in Preparation for Clinical Trial Enrollment

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Organicell Regenerative Medicine, Inc. Secures Additional $11 Million in Financing in Preparation for Clinical Trial Enrollment - Organicell MIAMI, FL / ACCESSWIRE / September 9, 2022 / Organicell Regenerative Medicine, Inc. (OTCQB:OCEL), a clinical-stage biopharmaceutical company focused

Organicell Regenerative Medicine, Inc. announced the broad-based engagement of top international law firm McDermott Will & Emery, widely considered to have the best health care practice in the nation.

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Organicell Regenerative Medicine, Inc. Engages Law Firm McDermott Will & Emery - Organicell MIAMI, FL / ACCESSWIRE / August 30, 2022 / Organicell Regenerative Medicine, Inc. (OTCQB:OCEL), a clinical-stage biopharmaceutical company principally

Organicell Regenerative Medicine, Inc. announced today that the board of directors has appointed Matt Sinnreich as Chief Operating Officer and acting CEO.

Organicell Announces Matt Sinnreich as CEO - Organicell MIAMI, FL / ACCESSWIRE / July 26, 2022 / Organicell Regenerative Medicine, Inc. (OTCQB:OCEL), a clinical-stage biopharmaceutical company principally

Organicell Regenerative Medicine, Inc. announced today that it has secured $4.0 million in funding to finance clinical trials of its products and for general working capital purposes. In addition, Organicell has agreed to implement changes in corporate governance and management.

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Organicell Regenerative Medicine, Inc. Secures $4 Million in Funding for Clinical Trials and Agrees To Restructure Management - Organicell MIAMI, FL / ACCESSWIRE / July 20, 2022 / Organicell Regenerative Medicine, Inc. (OTCQB:OCEL), a clinical-stage biopharmaceutical company principally

Tania del Rivero, Ph.D., is a Senior Scientist at Organicell and is an integral part of our team.

Dr. del Rivero is a highly analytical research scientist with over 12 years of experience working in biomedical research. Her field of expertise includes molecular biology, immunology, and neuroscience.

She has worked in many settings — both clinical and laboratory — recently overseeing multiple clinical research projects from residents and faculty at Aventura Hospital and Kendall Regional Medical Center in Miami, FL.

Additionally, she has worked in various research laboratories to develop novel drugs and study their biological effects in cell culture and animal models.

Dr. del Rivero earned her doctorate from Drexel University, where her thesis focused on the role of TNF in neuropathic pain and is the author of numerous publications covering subjects such as osteoporosis, spinal cord injury, inflammation, and neuropathic pain.

Ribonucleic acid, or RNA for short, is a nucleic acid present in all living cells. It has a similar structure to DNA, however, differs in that it is single-stranded, vs. the DNA’s double helix structure.

RNA has several functions — translating genetic information to the structure of the cell, regulating gene activity during development, cellular differentiation, and making proteins within the cells to name a few. Some viruses even use RNA as the genomic makeup.

There are 4 common types of RNA, with each one having an important role in the cell functions and protein synthesis:
⁠⁠
1️⃣Messenger RNA (mRNA): It’s main role is transcription — the beginning phase of making a protein from a DNA blueprint.⁠ ⁠ ⁠⁠
⁠⁠
2️⃣Transfer RNA (tRNA): Ensures the correct amino acids are put into the polypeptide chain in the correct order during the process of translation.⁠ ⁠ ⁠⁠
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3️⃣Ribosomal RNA (rRNA): Helps assemble proteins.⁠ ⁠⁠
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4️⃣MicroRNA (miRNA): A non-coding region of mRNA used in the promotion or inhibition of gene expression.⁠ ⁠ ⁠⁠

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Source: National Human Genome Research Institute

While both DNA and RNA carry genetic information, there are a few key differences that give them distinct roles in living organisms.

The main difference is their structure — DNA is a double-stranded molecule, while RNA is a single-stranded molecule.

They also have different functions in the human body. DNA stores and transfers genetic information, while RNA directly codes for amino acids and is the messenger between DNA and ribosomes to create proteins in the body.

DNA molecules are self-replicating, but RNA molecules can only be synthesized by transcription, which is the process of copying DNA into RNA.

In essence, DNA and RNA work hand-in-hand to provide your genetic makeup, but they have very different functions in that process.

Source: ThoughtCo

Today commemorates the passage of the Declaration of Independence by the Continental Congress on July 4, 1776.

Our flag symbolizes the birth of one nation represented by: Red for hardiness and valor, White for purity and innocence, and Blue for vigilance, perseverance, and justice.

One flag, One land, One nation evermore.

Happy Independence Day!🇺🇸

Cytoskeletal proteins make up the cytoskeleton portion of the cell (the cytoskeleton is similar to the bones in our body). They are proteins that make up microtubules, microfilaments, and intermediate filaments.

Cytoskeletal proteins respond to intracellular stresses, such as mitochondrial, endoplasmic reticulum, and oxidative stresses, and present themselves as a therapeutic target.

These proteins can be considered part of the exosome transportation process and can provide further insight into biomarkers for numerous diseases.

Source: National Library of Medicine

It’s and Organicell would like to recognize the significant advances made by women in biomedical engineering, such as:

💡Judy Sullivan: the lead biomedical engineer for NASA on the Apollo 9 and 11 missions. She was the first woman engineer to be hired by NASA for spacecraft testing.

💡 Rosalind Franklin: her work on X-Ray diffraction studies led to the discovery of the double-helix structure of DNA.

We would also like to recognize the current advances spearheaded by women in biomedical engineering, such as:

💡Gordana Vunjak-Novakovic, Ph.D.: leads the Tissue Engineering Resource Center at Columbia where her team focuses on engineering human tissues for regenerative medicine and studies of disease. She is one of the most-cited scientists of all time.

💡Kaitlyn Sadtler, Ph.D.: Chief of NIBIB’s Section for Immunoengineering developing new biomaterials for regenerative medicine and studying the immunology of wound healing and tissue growth.

💡Ranu Jung, Ph.D.: dedicated her career to developing neurotechnologies that provide recovery and repair lost function due to a neurological disability or trauma. Under her leadership, researchers have created the first wireless, implantable, neural-interface system for a prosthetic hand.

Without the dedication, persistence and determination of women engineers and scientists, biomedical and genetic science would not be what it is today.

Today we celebrate Juneteenth, commemorating the emancipation of enslaved African Americans.

Freedom finally came on June 19, 1865, when some 2,000 Union troops arrived in Galveston Bay, Texas, and disclosed to enslaved African Americans that they were free, more than two years after the Emancipation Proclamation was signed.

Happy Father’s Day!

Your blood is composed of several types of blood cells in a liquid known as plasma. Plasma is primarily water but also contains protein, salt, fats, and glucose.

Blood cells are made from stem cells within bone marrow. These stem cells are able to develop into the different types of blood cells and once mature and able to function, are released from the bone marrow into the blood.

The three types of blood cells are:

🩸 Red Blood Cells - carry oxygen to your cells using a protein called hemoglobin, which is what makes the blood-red. They also carry carbon dioxide away from cells to allow it to be exhaled by the lungs. Red blood cells make up the majority of blood cells.

🩸 White Blood Cells - are an integral part of the immune system because they fight infections by targeting bacteria and viruses that invade the body. The majority of white blood cells are found outside of the blood in other tissues, meaning there is normally a few amount of white blood cells in the blood.

🩸 Platelets - cause the blood to clot and stop bleeding by clumping together.

Source: Canadian Cancer Society

Every year, 4.5 million Americans will need a blood transfusion.

Today is — a day to raise awareness of the need for safe, life-saving, blood donations. Safe blood and blood products in a sufficient supply are a necessary part of an effective healthcare system.

The selfless donations of donors across the world can be used for patients receiving care for:

Auto accidents
Heart surgery
Organ transplants
Severe burns
Certain premature infant treatments
Joint replacements
Post-cancer treatments

To learn more about donating, please visit givingblood.org.

Source: givingblood.org

June is and Organicell would like to recognize LGBTQ+ individuals who have made incredible, and important, contributions to science.

🧪 Isaac Newton: an English mathematician, physicist, astronomer, alchemist, theologian, and author who is most widely known for developing the theory of gravity and laws of motion.

🧪 Ben Barres: a neurobiologist and elected member of the US National Academy of Sciences whose work on brain cells known as glia changed the way we understand how the brain operates.

🧪 Alan Hart: a prominent figure in fighting tuberculosis and served as the director of hospitalization and rehabilitation at the Connecticut State Tuberculosis Commission.

🧪 Sara Josephine Baker: founder and the first director of New York’s Bureau of Child Hygiene and pioneer of numerous disease prevention and education programs, including the prevention of a serious Typhoid outbreak in 1906.

🧪 Sophie Wilson: developed the Acorn Computer, a small personal computer that paved the way for modern mobile devices. The ARM processor is still used in over 60% of smartphone devices today.

Thank you to all LGBTQ+ scientists for your dedication and contribution to science.

Read more: https://www.asbmb.org/asbmb-today/people/061821/lgbtq-scientists-through-history

Enzymes are proteins found throughout the body that act as a catalyst for reactions and metabolism.

Enzymes can be found in all living cells and in extracellular vesicles. Each type of enzyme has a unique architecture which makes the enzyme highly specific, meaning a specific enzyme can only work with a specific reaction.

Essentially, enzymes mediate reactions throughout the body.

Extracellular Vesicles, such as exosomes, contain enzymes inside and on their surface.

Enzymes within exosomes act in cell-to-cell communication, delivering the enzymes to neighboring cells to stimulate a specific response. Whereas enzymes on exosome surfaces can be associated with the mobilization of growth factors, the degradation of macromolecules, and the destruction of amyloid β plaques.


Source: National Library of Medicine

Cells are quite an intuitive part of the body. They can detect what is happening around them and can respond in real-time to external stimuli.

They communicate via chemical signals, known as signaling molecules, which are secreted from the cell and then released into the extracellular space. They can then be transferred to neighboring cells.

This chemical signaling causes changes to the cell, such as the alteration of a gene or cell decision.

Signaling cells can be broken down into four categories:

➡Paracrine signaling: where cells communicate through short distances, allowing localized activity.
➡Synaptic signaling: where nerve cells transmit signals between another nerve cell.
➡Autocrine signaling: a cell that signals to itself to release a ligand to bind to receptors on its surface or within its own cell.
➡Endocrine signaling: long-distance signaling that is produced by specialized cells that are released into the bloodstream.

Source: National Library of Medicine

Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory lung disease that obstructs airflow from the lungs.

COPD is most commonly caused by long-term exposure to irritating particulate matter, such as cigarette smoke. Those with COPD are at high risk for developing other conditions, including heart disease and lung cancer.

COPD is a progressive disease and currently affects over 15 million Americans, with nearly 150,000 COPD related deaths each year.

Common symptoms include:

🫁 Shortness of breath
🫁 Wheezing
🫁 Fatigue
🫁 Chronic, mucus-producing cough
🫁 Chest tightness

While COPD is not curable, prevention is the best way to manage this disease. An alarming approximation of 90% of smokers begin before 18 years old, with the average being 13 years old. The most effective intervention in stopping the progression of COPD is to stop smoking early into adulthood.

Learn more about Organicell’s involvement with COPD - https://orga​​nicell.com/2021/01/28/organicell-announces-fda-approval-of-ind-application-for-the-use-of-zofin-in-the-treatment-of-chronic-obstructive-pulmonary-disease-copd/)

Source: CDC

On the last Monday of May, we remember and honor those who served and sacrificed for our country
Originally called Decoration Day, Memorial Day originated in the post-Civil War period and was declared a federal holiday in 1971.
Americans observe this day by visiting cemeteries, memorials, gathering with family, and participating in parades. Each year a national moment of remembrance occurs at 3 pm local time for Americans to pause and pay their respects.
Today does not just mark the start of a new season — it's an opportunity for Americans to remember the thousands who have laid down their life to protect the freedom and safety of their country, as well as offer support for their families who continue to grieve.

Ivan Santos is the Biologics Manufacturing and Operations Manager at Organicell. Experienced in regenerative medicine, Ivan has a strong ability to translate design requirements into actionable plans. He brings valuable experience in biotechnology and neuroscience research, and is a key contributor to the development of novel therapeutics at Organicell.

Ivan is immensely adept with biologic quantification techniques such as ELISA assays, bradford analysis, flow cytometry, nanosight technology, and is skilled in biologic processing such as exosome isolation, and cell culturing and expansion.

He also has extensive experience with MATLAB/Simulink, Wolfram Mathematics, and Python, contributing qualitative analysis programing to biologic research and manufacturing.

This week is the ISEV Annual Meeting in Lyon, France. brings together scientists from academic, clinics, and industry, who have a common goal of understanding EVs and applying this knowledge for societal and economic benefit.

Join Organicell May 25-29th for our abstract presentation on “Small RNA sequencing of amniotic fluid-derived extracellular vesicle cargo reveals diverse RNA types”.

Conference agenda: https://www.eventscribe.net/2022/ISEV2022/aaStatic.asp?SFP=TE5aWFlKWEZAMTAwOTRAUHJvZ3JhbSBhdCBhIEdsYW5jZQ