LivaNova

We appreciate the creative “Patients First” thinking of LivaNova UKI team team member Natalie Bailey. She helped a Consultant Neurosurgeon in Hull, UK, move an important VNS Therapy™ procedure out of the main hospital to a day case surgery unit.

Mr. Adam Razak worked tirelessly, with Natalie’s support, to make this move so patients could get more timely battery replacements for their VNS Therapy devices. Mr. Razak and his colleagues are among the first in the country to conduct battery changes in a dedicated day surgery facility.

This change lowers the numbers of procedure cancellations or delays, eliminates the need for hospital admission, and reduces the waiting list for battery replacements. It also alleviates pressure on theatre sessions at the main hospital, Hull Royal Infirmary.

“The new Day Surgery Centre at Castle Hill Hospital offers a much more modern and suitable facility in which to be providing VNS Therapy battery replacements, and we’re proud to be involved in delivering this type of surgery, and supporting local patients, in such a pioneering way,” Natalie said.

In London recently, 25 senior leaders met at Talent & Leadership Connect, a cross-functional meeting of international leaders from LivaNova’s European, MEA, and APAC regions.

They engaged and collaborated on key strategic topics such as innovation, culture, market expansion, external collaboration, ESG, talent, and data analytics. The Board of Directors and ELT members attended select items on the agenda, giving participants an opportunity to speak informally with the Company’s top leaders.

It was a lively, energized, and fun meet-up, and we’re grateful to both organizers and attendees for making this engaging three-day event happen.

At TEDx Mirandola in June 2024, speakers from leading companies in the biomedical district of Mirandola, Italy, and beyond explored the theme “ONE HEALTH - Sustainable for Human,Animal,Environment.”

The theme – which explores how individual well-being is intrinsically linked to that of the surrounding area, society, and the planet – is also the basis of the environmental sustainability path adopted by LivaNova in the development of its Mirandola production site.

Marco Medici, Sr. Technical Leader, Disposables Engineering for LivaNova Cardiopulmonary, detailed some of the optimizations the Mirandola production site has implemented as part of LivaNova’s goal of net-zero greenhouse gas emissions by 2050. They include:

• Separation of plastics amongst cleanroom waste to increase recycling
• Packaging redesign to reduce waste
• Optimization of lighting and room temperature control to reduce waste
• Improvements to the degassing energy and sterilization cycle to reduce ethylene oxide (EO) and nitrogen (N2) consumption

“Collaboration of ideas and actions has been critical in allowing us to take the first decisive steps in recognizing sustainability as a central theme for our site,” Medici said on stage. “Sustainability is a challenge that can only be met together, beyond the business differences of each of the realities in our district.”

For the second consecutive year, LivaNova hosted a delegation of 20 master's students from the University of Palermo on an educational trip to the Mirandola Biomedical Valley.

The students toured LivaNova’s manufacturing plant and research and development laboratories. They also attended a lesson on cardiopulmonary bypass and a course on the use of virtual prototyping techniques in the design process of oxygenators.

The students showed a lot of interest in seeing the practical applications of their Biomedical Engineering Course.

“For nearly five decades, Americares has been working to save lives and improve health for people around the world. I am honored to join the Americares board and look forward to helping advance its mission,” said Vladimir Makatsaria.

We are excited to announce the election of Vladimir Makatsaria to the Board of Directors! CEO and board member of
LivaNova, Makatsaria brings nearly 30 years of experience in the global pharmaceutical and medical device industry. We look forward to his partnership as we continue our work to create a world where every person – everywhere – has a fair and just opportunity to live their healthiest life. Read more about his announcement here: https://www.americares.org/news/vladimir-makatsaria-joins-americares-board-of-directors/

Join us for a virtual educational event about a research study on a different approach to Difficult-to-Treat Bipolar Depression. Questions are encouraged and many will be answered during the live event, Tuesday, July 30, at 8 p.m. Eastern Time. Register: https://livn.info/4cRXl48

We are proud to share that, in the last few months, the LivaNova team in Costa Rica hit several significant milestones! 🌟

The installation of a new Essenz Perfusion System was followed by an intensive day of training and hands-on sessions, ensuring the O.R. team is ready and confident to integrate LivaNova’s perfusion system into daily practice.

Just a few days later, the first clinical case was successfully completed. The perfusion team was pleased with the outcome and confirmed the system performed as expected.

In addition to that, LivaNova team had the privilege of presenting Essenz Perfusion System to more than 150 attendees, including hospital directors, cardiac surgeons, National Funds, and patients from all over Costa Rica.

Welcome Hospital Nacional de Niños San José to the ! Together we are making a difference in patients’ lives.

Enter the New Era: www.essenzperfusion.com



-

Estamos orgullosos de compartir que el equipo de LivaNova LATAM en Costa Rica alcanzó varios hitos importantes en Mayo! 🌟

A la instalación del un nuevo sistema de perfusión Essenz le siguió una semana de intensivo de entrenamiento y sesiones prácticas, lo que garantizó que los Perfusionistas estan preparados y seguros para integrar el sistema de perfusión de LivaNova en la práctica diaria.

Pocos días después se completó con éxito el primer caso clínico. El equipo de perfusión quedó satisfecho con el resultado y confirmó que el sistema funcionó como se esperaba.

Además de eso, el equipo de LivaNova tuvo el privilegio de presentar el Sistema de Perfusión Essenz a más de 150 asistentes, entre ellos directores de hospitales, cirujanos cardíacos, Fondos Nacionales y pacientes de todo Costa Rica.

¡Bienvenido Hospital Nacional de Niños de Costa Rica la ! Juntos estamos marcando una diferencia en la vida de los pacientes.

Entre en la nueva Era de la Perfusión: www.essenzperfusion.com

It is so gratifying to support the next generation of perfusionists who will make a significant impact on patient care!

Last week, we had the pleasure to welcome 12 newly qualified perfusionists from the United Kingdom and Ireland to our plant in Mirandola, Italy.

Our goal was to provide them with firsthand insights into our manufacturing processes, introduce our comprehensive company portfolio, and showcase the Essenz Perfusion System.

This 2-day educational visit empowered participants with knowledge and inspiration to apply to their practices.

Here's to supporting and shaping the future of perfusion together! 💙

Recently, Ahmet Tezel, LivaNova’s newly appointed Chief Innovation Officer, Badri Amurthur, Chief Technology Officer, and Trui Hebbelinck, Chief Human Resources Officer visited our Mirandola and Milan sites to meet with our teams, embrace our core values with a focus on meaningful innovation.

From product development to process improvements, the team dove straight into the opportunities that will keep us at the cutting edge of innovation while maintaining a strong focus on process efficiencies and quality offerings for our patients.

Thank you, Ahmet, Badri and Trui for engaging so openly with our Italian teams and providing further proof of the impactful work they do in ensuring our success.

We are honored to be in Bologna this week at the 1st World Summit for Pediatric and Congenital Heart Surgery.

We are always inspired by the dedication OR teams demonstrate as they care for young patients, and by the strength these patients and their families bring to every surgery.

If you are at the event, connect with our Cardiopulmonary team at Booth 19.

To check a list of events where you can find us with our latest innovations and get a closer look at the , visit: https://cv.livanova.com/en-uk/events

LivaNova today announced preliminary results for the unipolar cohort of the RECOVER study, assessing use of VNS Therapy in treatment-resistant depression. While the study did not meet its primary endpoint (PE) for the unipolar cohort, statistical significance was achieved in select secondary endpoints.

Read more in our press release: https://livn.info/4bPuZrc

Os esperamos en Madrid en el XXVII Congreso de la Sociedad Española de Cirurgia Cardiovascular y Endovascular y el XXIII Congreso de la Asociación Española de Perfusionistas.

Venga a visitarnos hasta el 7 de Junio para descubrir la bomba y todas las lineas de productos cardiopulmonares de LivaNova.

Para más información sobre Essenz Perfusion System, visite: www.essenzperfusion.com

Every day, every month we take knowing that LivaNova is diverse by nature, united by purpose.

The Company embraces diverse perspectives, experiences and backgrounds, knowing they enrich collaborative culture and drive success as a company.

Diversity and inclusion create trust and a deeper sense of belonging to the LivaNova community, uniting the Company to make a meaningful difference in the lives of patients worldwide. LivaNova recognizes the value in fostering a work environment that is culturally diverse and inclusive and strives to provide a workplace free of harassment or discrimination.

Mental Health Awareness Month may be ending, but every day provides a new opportunity to destigmatize mental health. We at LivaNova would like to thank you for your role in making this happen. We have a favor to ask in this last post of the month: Remember 988.

If you or someone you know is struggling or in crisis, help is available.
Call or text 988 or use the chat at 988lifeline.org to reach the 988 Su***de & Crisis Lifeline.

The 988 Lifeline responds 24/7 to calls, chats or texts from anyone who needs support for suicidal, mental health and/or substance use crisis and connects those in need with trained crisis counselors. Please share. You could save a life!

#988

In this information-packed webinar co-presented by LivaNova and the International Bipolar Foundation, Dr. Alva and Lana discuss VNS Therapy™ from their own unique perspectives. This presentation explains what VNS Therapy is and the benefits it can provide in everyday life, as well as in-depth clinical details. Watch now: https://livn.info/3WCHemi

Depressive symptoms may improve slowly over the first year of treatment with VNS Therapy, which is a long-term adjunctive (add-on) treatment for patients 18 years of age and older who are experiencing a major depressive episode and have not had an adequate response to four or more adequate antidepressant treatments. All treatment decisions should be discussed with a physician. Safety information: https://livn.info/3Pzeju2

New hires often bring fresh perspectives and potential, and we are proud to give them the opportunity to get to know our business.

Last week the European Cardiopulmonary Marketing team trained many new colleagues from all over the world! They started from the basics of anatomy and went deeper into the entire cardiopulmonary product portfolio.

At LivaNova, learning and progression strengthen our capabilities to serve patients around the world.

Thanks to all participants for your active engagement, and to our trainers for your guidance and enthusiasm!

Caregivers play an essential role in helping the millions of people in the U.S. who experience mental health conditions each year. They are on their own unique journey to hope and also need support — from tips on how best to support their loved one, to crisis prevention and self care pointers.

Check out these caregiver resources from the National Alliance on Mental Illness (NAMI): https://www.nami.org/Your-Journey/Family-Members-and-Caregivers

The Heart Center at the HagaZiekenhuis Hospital in The Hague, Netherlands, is the regional center of expertise for heart disorders, continuously focused on improving cardiac care for patients.

They are now proud adopters of the Essenz Perfusion System, having purchased and put into clinical use four of these next-generation devices. This center is proud to have been operating with a MiECC system for around 20 years, and they are among the first hospitals in the world to utilize this setting with an Essenz Perfusion System!

“With Essenz, we are more able than ever to offer patient-tailored treatments. We can respond quickly and efficiently to the patient’s needs and adapt to changing circumstances," says perfusionist Van Appeldorn on behalf of the perfusionists at HagaZiekenhuis The Hague, who are part of the Heartbeat Dutch Perfusion Service.

“The device also facilitates an efficient workflow, and by integrating the perfusion information within our Health Information System, we can examine large patient groups and draw learnings to continuously improve the quality of our treatments,” concluded Mr Van Appeldorn.

Thank you to the team at the Heart Center for their commitment to patients and for joining the !

For more information on the Essenz Perfusion System, visit: www.essenzperfusion.com



Please note: Essenz Perfusion System comprises the Essenz HLM with sensing technology and Essenz Patient Monitor. Information about the Essenz Perfusion System is only available in selected geographies. Visit essenzperfusion.com for important safety information.