Epic Bio

Our company is based on the science of our founder, Stanley Qi, one of the original CRISPR co-invent

03/28/2024

Today, for Women's History Month, we're honoring the achievements of Barbara McClintock, a pioneering scientist whose work revolutionized the field of genetics. McClintock's research on maize led to the discovery of jumping genes, challenging existing paradigms. Her work earned her the Nobel Prize in Physiology, making her the first woman to receive an unshared Nobel Prize in that category.

McClintock's dedication to her work, her innovative thinking, and her unwavering commitment to scientific discovery continue to inspire to this day. Her legacy serves as a reminder of the importance of perseverance, curiosity, and passion in pursuing knowledge.

03/26/2024

Today for Women's History Month, we honor the pioneering Edith Clarke! She holds the distinction of being the first professionally employed female electrical engineer in the United States and the first woman to present a paper at the annual meeting of the American Institute of Electrical Engineers. Edith overcame significant challenges in a male-dominated field, leveraging her education and skills to pave the way for future generations of women in engineering.

Edith's journey began with a Bachelor of Science degree in Mathematics from Vassar College in 1908. She continued her studies, earning a master's degree in electrical engineering from the Massachusetts Institute of Technology (MIT) in 1919. Despite encountering difficulties in finding employment due to her gender, Edith's perseverance and passion for engineering led her to a successful career.

One of her more notable contributions is the "Clarke Calculator," a graphical tool that simplified and reduced the workload for engineers analyzing characteristics of long electrical transmission lines. Edith applied for a patent for her graphical calculator in 1921, which was granted in 1925.

Epigenetic Editing Explodes on the Heels of Gene Editing Success | BioSpace 03/25/2024

"Epigenetic editing therapies may also avoid the potential side effects of CRISPR-based approaches, said Dan Hart, head of technology development at Epic Bio, which is developing an epigenetic editing treatment for facioscapulohumeral muscular dystrophy (FSHD). During gene editing, unintended cuts in the DNA can lead to unwanted cell growth and cancer. “So then the pressure is on to find improvements and innovations, and now you see the shift to . . . what else can we do? Where else can we go?” Hart said."

https://ow.ly/C0LG50R1sGR

Epigenetic Editing Explodes on the Heels of Gene Editing Success | BioSpace Ubiquitous potential, possible safety advantages and the recent growth of cell and gene therapy are driving investment in a different type of genetic editing.

03/21/2024

Today, as we continue to celebrate the achievements of women in science, we honor Dr. Mary Putnam Jacobi, a pioneering figure in medicine whose contributions reshaped our understanding of women's health. Dr. Jacobi was not only the first woman to attend Ecole de Medicine in Paris but also a prolific author whose scientific publications challenged prevailing notions about women's bodies.

Dr. Jacobi is also known for debunking myths surrounding women's menstruation in writing a paper challenging a Harvard professor's book on the subject, which was often shrouded in misinformation. Her work paved the way for a more informed and compassionate approach to women's health.

03/19/2024

Today, during Women's History Month, we pay tribute to Rebecca Lee Crumpler, an extraordinary trailblazer in the field of medicine. As the first Black woman to earn a medical degree in the United States, Crumpler's legacy is a beacon of inspiration for generations to come.

Rebecca Lee Crumpler shattered barriers and defied norms in pursuit of her passion for healing. Despite facing immense obstacles due to her gender and race, she persevered with unwavering determination and resilience.

One of Crumpler's notable achievements was the publication of "A Book of Medical Discourses" in 1883. This work was one of the first medical publications by a Black author in the United States, highlighting her exceptional knowledge and expertise in the field of medicine.

Crumpler's achievements paved the way for countless women and people of color to pursue careers in medicine. Her courage and dedication continue to inspire us to break down barriers and strive for excellence in all endeavors.

03/14/2024

🥧 Happy Pi Day from Epic Bio! 🥧

Today, we're celebrating not only our love for science but also our talent for baking! Who knew our team could whip up more than just great experiments? Some of us even made cakes... 🎂😅

Congratulations to our Pi Day baking contest winners! 🏆🥇 Hao took first place with her Cookie Butter Pie, Thomas sliced into second place with his delicious Apple Pie, and Andrew grabbed third with his decidant "Chocolate Cheesecake Pie."

Whether you're calculating the circumference of a circle or the perfect crust-to-filling ratio, we hope your Pi Day is as sweet as π itself!

03/14/2024

Today, we honor the pioneering scientist Esther Lederberg, whose groundbreaking work revolutionized microbiology. Esther's research laid the foundation for our understanding of genetic recombination and bacterial genetics. Her discoveries paved the way for countless advancements in medicine and biotechnology.

Despite facing gender bias in the scientific community, Esther persevered, becoming a trailblazer for women in STEM. Her dedication, intellect, and passion for science continue to inspire us today.

03/13/2024

Today, we announced that Dr. Amber Salzman., chief executive officer, will present at the Charles River Cell & Gene Therapy Summit at 2:00 p.m. PT, Tuesday, March 19, 2024, in South San Francisco. Institutional investors can learn more about this event and register to attend here: https://ow.ly/ZiIj50QSGl8

03/08/2024

This International Women's Day, we celebrate the incredible contributions and achievements of women around the world. At Epic Bio, we are proud to have remarkable women who drive innovation, lead with compassion, and inspire us every day.

From the boardroom to the bench, women play a pivotal role in shaping our organization's success. Their resilience, creativity, and dedication make us stronger, and more innovative.

Happy International Women's Day!

03/05/2024

To celebrate Women's History Month, we want to highlight the groundbreaking work of Rosalind Franklin, a brilliant scientist whose crucial contribution to the discovery of the double helix structure of DNA paved the way for modern genetics. Despite facing significant challenges and not receiving the recognition she deserved during her lifetime, Franklin's pioneering research laid the foundation for our understanding of the molecular basis of life. Her legacy continues to inspire future generations of scientists, especially women in STEM, to pursue their passion and push the boundaries of knowledge. Read more here: https://ow.ly/PI5m50QLRy2

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02/29/2024

There is strength in rarity! Today, on Rare Disease Day, let's raise awareness and support those bravely facing uncommon health challenges. We can amplify their voices, foster understanding, and promote research. Learn more at https://www.rarediseaseday.org

02/27/2024

As work-life balance becomes increasingly important in today's fast-paced world, our team has prioritized unwinding and connecting with each other at our monthly happy hour and other monthly events. This time allows us to socialize, relax, and strengthen relationships in and outside the office.

02/22/2024

Epigenetics is a hot topic these days, not just in scientific circles but even in pop culture! For example, Netflix’s “You Are What You Eat” documentary follows identical twins who are assigned different diets; their health impacts are measured, in part, by looking at changes in their epigenomes.

This growing “buzz” reflects our deepening scientific understanding of how powerful epigenetics is in controlling human health. Epigenetic marks serve as notes that instruct each cell how and when to execute the correct genetic programs essential for maintaining our health and survival. This system is dynamic, responding to signals from our environment, such as diet, temperature, and even the time of day.

At Epic Bio, we are tapping into the power of epigenetics to change the activity of cells, without making permanent edits to the DNA. We’re leveraging the programmability of CRISPR gene-editing systems to develop epigenetic editing therapies. These therapies can selectively upregulate or downregulate critical genes to restore healthy cell functions in disease without making cuts or edits to the genome itself.

Furthermore, we have miniaturized these tools to enable precise delivery to the correct cells in living organisms, ensuring lasting therapeutic benefits.

Learn more on our website: https://epic-bio.com/science/

02/21/2024

Meet Epic Bio team member Andrew Norton, one of our exceptional scientists whose translational expertise in assay development helps to better characterize our therapeutic candidates.

02/16/2024

Wishing everyone a safe and enjoyable Presidents' Day weekend! Presidents' Day was originally established to celebrate George Washington's birthday and has since evolved into a day honoring U.S. presidents. However you're spending the long weekend, we hope it's filled with relaxation and good company.

02/01/2024

Embracing the legacy, honoring the resilience! February is more than just a month; it's a celebration of Black History. Join us to commemorate the achievements, contributions, and rich culture shaping our world. Together, we can amplify Black voices, share stories, and stand united in the pursuit of equality. Happy Black History Month!

11/22/2023

Feeling thankful for all of our supporters 🥰

Epigenetics: Can we control our genes? - BBC Reel 11/08/2023

Medicine is entering a new era where we can treat disease by altering our epigenome rather than rewriting our genetic code. This insightful video from BBC explains some of the fascinating scientific discoveries in epigenetics, including its role in certain diseases like the ones we at Epic aim to treat with .

Epigenetics: Can we control our genes? - BBC Reel For a long time, scientists believed that it wasn’t possible to alter our genetic code. Now, epigenetics is changing the game.

10/31/2023

“We are proud to partner with Kite Pharma to extend the potential application of Epic’s platform for cancer treatment. Epic’s approach is promising for in vivo medicines and may enable next-generation cell therapies to reach a wide range of patient populations.” Amber Salzman, Ph.D., CEO, Epic Bio.

10/26/2023

This week at , the Epic Bio team presented improvements upon CasMINI, previously the smallest Cas protein known to work in human cells. Additionally, we shared progress of our epigenetic editing platform and lead candidate EPI-321 for the treatment of FSHD. Read more here: https://ow.ly/6aRF50Q1aSH

10/26/2023

This week at , the Epic Bio team presented improvements upon CasMINI, previously the smallest Cas protein known to work in human cells. Additionally, we shared progress of our epigenetic editing platform and lead candidate EPI-321 for the treatment of FSHD

10/26/2023

This week at , the Epic Bio team presented improvements to , previously the smallest Cas protein known to work in human cells. Additionally, we presented progress on our lead program, EPI-321, for the treatment of FSHD. Read more here: https://ow.ly/fFiO50Q19p5

10/19/2023

We are pleased to share that Epic Bio will present at the European Society of Gene and Cell Therapy conference October 24-27 in Brussels, Belgium. Read more here: https://ow.ly/wWO150PYFuQ

10/17/2023

Epic Bio strengthens the leadership team by appointing Weston Miller as Chief Medical Officer. Read more here: https://ow.ly/JjG150PXKKs

10/16/2023

It was great to attend today and be honored for our win. Thanks, , for the recognition and , for the nice trophy we’ll display in our office!

10/12/2023

"🌍✨ Today is , a global initiative to raise awareness about vision impairment and blindness. Sight is a precious gift, and together, we can work towards a world where everyone has the opportunity to see the beauty around them. 👁️

10/05/2023

CEO, Amber Salzman, Ph.D., will present at the BMO Private Company Showcase on Thursday, October 12, 2023, in New York, NY. Institutional investors interested in meeting with management during the conference may contact their BMO representative. https://ow.ly/sNqT50PTxF4

09/28/2023

We are pleased to share that Epic Bio will present at the International Annual Congress of the World Muscle Society. Read more here: https://epic-bio.com/news/

09/28/2023

We are pleased to share that Epic Bio will present at the International Annual Congress of the World Muscle Society. Read more here: https://ow.ly/ACTr50PQJ2X

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Videos (show all)

🥧 Happy Pi Day from Epic Bio! 🥧Today, we're celebrating not only our love for science but also our talent for baking! Wh...
Today, we announced that Dr. Amber Salzman., chief executive officer, will present at the Charles River Cell & Gene Ther...
As work-life balance becomes increasingly important in today's fast-paced world, our team has prioritized unwinding and ...
Epigenetics is a hot topic these days, not just in scientific circles but even in pop culture! For example, Netflix’s “Y...
Wishing everyone a safe and enjoyable Presidents' Day weekend! Presidents' Day was originally established to celebrate G...
“We are proud to partner with Kite Pharma to extend the potential application of Epic’s platform for cancer treatment. E...
This week at #ESGCT23, the Epic Bio team presented improvements upon CasMINI, previously the smallest Cas protein known ...
This week at #ESGCT23, the Epic Bio team presented improvements upon CasMINI, previously the smallest Cas protein known ...
This week at #ESGCT23, the Epic Bio team presented improvements to #CasMINI, previously the smallest Cas protein known t...
Epic Bio CEO Amber Salzman, Ph.D., to participate in a panel discussion on epigenomic medicines and rare diseases at the...
New data detail the discovery and engineering of hypercompact transcriptional activation domains with greater magnitude ...
Epic Bio Announces Presentations at Upcoming Scientific and Medical Conferences.Follow the link to learn more: http://ow...

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