Makra Medical Lecture

ការបកស្រាយ ហេតុអ្វីក្រុមថ្នាំ Loop Diuretic ធ្វើឲ្យមាន Hyperglycemia

Note: Insulin ចាប់ glucose គ្រាន់ជាពាក្យចំណាំថា "Insulin បន្ថយ Glucose" ការពិត Insulin មិនបានចាប់ ឬមានសកម្មភាពប៉ះពាល់ Glucose ដោយផ្ទាល់ឡើយ។

សូមភ្ជាប់ឯកសារយោងមួយចំនួនស្តីពីទំនាក់ទំនង Diuretics និង Diabetes:
1. Medscape: https://www.medscape.com/viewarticle/489521
2. American Heart Association: https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.120.048739
3. NIH: https://www.ncbi.nlm.nih.gov/books/NBK546656/
4. Wiley: https://onlinelibrary.wiley.com/doi/full/10.1002/ejhf.2220
5. European Society of Cardiology: https://www.escardio.org/

23/05/2023

Why drugs in the catecholamine group aren't given orally.

03/05/2023

Bronchitis in Children
Source: WHO's guide on Antibiotics therapy

30/04/2023

យើងនឹងជួបគ្នាពី Myasthenia Gravis នៅថ្ងៃស្អែកវេលាម៉ោង 6:00pm ល្ងាច។

27/04/2023

The new video talks about Myasthenia Gravis, an autoimmune disease in neurology, which will be released this Sunday. We will deep dive into the normal mechanisms in the physiology of processing neuromuscular signal transmission at junctions. Then we take a trip to see how the immune causes disturbance of this process leading to a disease, called Myasthenia Gravis.

20/04/2023

ការសិក្សាពីសកម្មភាព Caffeine លើ Adrenergic receptor
- សង្ខេបពី Adrenergic Gs Pathway
- សារះសំខាន់នៃ cAMP
- ការបង្កើត cAMP និង ការបំបែក cAMP
- ទំនាក់ទំនងរវាង cAMP និង Adenosine
- ទំនាក់ទំនងរវាង Gs និង Gi pathway
- សារះសំខាន់របស់ Adeonsine
- ទំនាក់ទំនងរវាង Adenosine និង Caffeine
- សកម្មភាពរបស់ Caffeine
- គុណសម្បត្តិ៍ និងគុណវិបត្តិរបស់ Caffeine
- របៀបញុាំកាហ្វេឲ្យបានត្រឹមត្រូវដើម្បីបញ្ជៀសគុណវិបត្តិ

ខ្ញុំសូមភ្ជាប់ឯកសារសិក្សាមួយចំនួន
1. Caffeine for the Sustainment of Mental Task Performance:
https://www.ncbi.nlm.nih.gov/books/NBK223802/
2. Caffeine and the central nervous system: mechanisms of action, biochemical, metabolic, and psychostimulant effects: https://www.sciencedirect.com/science/article/abs/pii/016501739290012B
3. Caffeine Pharmacology: https://www.news-medical.net/health/Caffeine-Pharmacology.aspx
4. Caffeine as a psychomotor stimulant: mechanism of action: https://link.springer.com/article/10.1007/s00018-003-3269-3
5. Caffeine's Vascular Mechanisms of Action: https://www.hindawi.com/journals/ijvm/2010/834060/

20/04/2023

ការសិក្សាពីសកម្មភាព Caffeine លើ Purinergic receptor
- សង្ខេបពី Adrenergic Gs Pathway
- សារះសំខាន់នៃ cAMP
- ការបង្កើត cAMP និង ការបំបែក cAMP
- ទំនាក់ទំនងរវាង cAMP និង Adenosine
- ទំនាក់ទំនងរវាង Gs និង Gi pathway
- សារះសំខាន់របស់ Adeonsine
- ទំនាក់ទំនងរវាង Adenosine និង Caffeine
- សកម្មភាពរបស់ Caffeine
- គុណសម្បត្តិ៍ និងគុណវិបត្តិរបស់ Caffeine
- របៀបញុាំកាហ្វេឲ្យបានត្រឹមត្រូវដើម្បីបញ្ជៀសគុណវិបត្តិ

ខ្ញុំសូមភ្ជាប់ឯកសារសិក្សាមួយចំនួន
1. Caffeine for the Sustainment of Mental Task Performance:
https://www.ncbi.nlm.nih.gov/books/NBK223802/
2. Caffeine and the central nervous system: mechanisms of action, biochemical, metabolic, and psychostimulant effects: https://www.sciencedirect.com/science/article/abs/pii/016501739290012B
3. Caffeine Pharmacology: https://www.news-medical.net/health/Caffeine-Pharmacology.aspx
4. Caffeine as a psychomotor stimulant: mechanism of action: https://link.springer.com/article/10.1007/s00018-003-3269-3
5. Caffeine's Vascular Mechanisms of Action: https://www.hindawi.com/journals/ijvm/2010/834060/

17/04/2023

លម្អឹតពីធាតុផ្សំសំខាន់របស់ Membrane និងតួនាទីធាតុផ្សំនិមួយ។
+ Lipid:
- Phospholipid
- Cholesterol
- Glycolipids
+ Protein
- Intergral Protein (Transmembrane protein)
- Peripheral Protein (Extra vs Intra membrane protein)

Photos from Makra Medical Lecture's post

17/04/2023

Pharyngitis in Children

16/04/2023

Pediatric normal vital signs and Hemodynamic Assessment

15/04/2023

Happy Khmer New Year!

14/04/2023

លម្អឹតអំពី Primary Active Transport
- Na/K ATPase
- Ca2+ ATPase
- Proton pump

13/04/2023

HBV lab markers and clinical practice

12/04/2023

នេះជាប្លង់ដែលខ្ញុំនឹងបកស្រាយពីសកម្មភាពរបស់សារធាតុកាហ្វេ Caffeine ។ Caffeine នេះមិនមែនមានតែក្នុងកាហ្វេទេ សព្វថ្ងៃគេប្រើវាក្នុងភេសជ្ជៈប៉ូវកម្លាំងនានាដែលខ្ញុំសូមមិនបញ្ជេញឈ្មោះជាសាធារណៈ (លើកលែងក្នងការសិក្សាលក្ខណ professional) ។

ខ្ញុំក៏នឹងផ្សារភ្ជាប់ផងដែរជាមួយមូលហេតុនៃការញៀនកាហ្វេ (ខ្ញុំចូលចិត្តហៅ Caffeine tolerance ជាជាងការហៅថាញៀន)។ បញ្ជាក់÷ កាហ្វេមិនអាក្រក់ទេ ល្អជាងសារធាតុផ្សេងៗនៅគ្រួសារជាមួយវា។

12/04/2023

ចំណុចសំខាន់ៗជាពត៌មានដើម្បីថែរក្សារខ្លួនកំឡុងពេលអាកាសធាតុក្តៅ

11/04/2023

Active Transport
- Primary active transport
- Secondary active transport
- Important of Na/K ATPase
- Example of Cotransport vs Exchanger
- Transportation of amino acid, glucose, Na, K, Cl, Ca, and Proton

Previous related video: https://fb.watch/jQT-lqZV24/

10/04/2023

Membrane Transport: Passive Transport 2
- Facilitated Diffusion
- Glucose Transporter Type 2 in (GI Tract and Renal Tubular)
- Na and K Channel

Previous related video: https://fb.watch/jPRMC4sXaa/

10/04/2023

Tonight's Topic: Facilitated Diffusion

08/04/2023

Membrane Transport: Passive transport
- Simple diffusion
- Factors that affect diffusion
- Fick's law

Previous related Video: https://www.facebook.com/watch?v=3348862438666666

07/04/2023

Overview of Membrane Transport
ការណែនាំពីការ Transport របស់ Membrane

07/04/2023

Welcome to the Page, a community of people who are currently working or studying in the medical field.

Do you find that physiology is hard to understand? What about pharmacology? Curious what's new discoveries like the pathogenesis of Covid-19 as an example? How are variants and viruses like the new bird flu virus? This page will help you in understanding those. Consider it as a backup tool that helps you in making complex mechanisms become more sense and simple.

I usually post a new video at 8:30pm-9:00pm

Anyway, I don't recommend it to be considered as reference documents or guidelines. I also don't give prescriptions so always consult your doctors. I just want to help and share medical knowledge.

Thanks for joining.

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