South East European Journal of Immunology

New Article of 2024 Now Available!
We are pleased to announce the release of a new article for 2024, titled “Atopic Dermatitis as a Precursor to Early Onset of Recurrent Wheeze, Bronchiolitis, and Childhood Asthma”. The article will be also co-published on Sciendo.
We would like to extend our sincere appreciation to Valentina Risteska-Nejasmic for the support and valuable input to our journal.

Atopic Dermatitis as a Precursor to Early Onset of Recurrent Wheeze, Bronchiolitis, and Childhood Asthma INTRODUCTION: Childhood asthma frequently escapes timely diagnosis, a consequence of inadequate parental education, societal prejudices, and health-care professionals’ limited knowledge. Bringing attention to atopic dermatitis (AD) as an early indicator of childhood asthma can enhance awareness ab...

Dear Esteemed Researchers,

On behalf of the editorial team at the Scientific European Journal of Immunology (SEEJIM), we extend a warm invitation for you to submit your research manuscripts for publication consideration.

SEEJIM is an international, modern journal covering all areas in the immunological sciences (sections), from basic immunology, clinical immunology, immunogenetics, and allergology. Published on prominent platforms including Sciendo and MyScienceWork SEEJIM ensures wide visibility for your academic work. We welcome submissions across topics within immunology, including original research articles, reviews, case studies, and perspectives, contributing to collective disciplinary growth. Your valuable research helps expand our understanding and knowledge in the field.

Submitting to SEEJIM offers benefits like rigorous peer review, efficient publication procedures, enhanced visibility, and access to a diverse readership. To submit your manuscript, please visit our online submission portal [https://seejim.eu/index.php/seejim/about/submissions] and follow the instructions provided. Article processing charge, also known as a publication fee for the SEEJIM is 300 EUR (https://seejim.eu/index.php/seejim/APC).

Thank you for considering SEEJIM as a platform to share your research. We look forward to collaborating in advancing immunological knowledge.

Warm regards,
SEEJIM Editorial Team

New Article of 2024 Now Available!
We are pleased to announce the release of a new article for 2024, titled “Toxic epidermal necrolysis: Case report and review”. The article will be also co-published on Sciendo.
We would like to extend our sincere appreciation to Hristina Breshkovska, Silvija Duma, Suzana Nikolovska, Ivana Dohceva-Karajovanov, Julija Telenta-Mitrova, Hristijan Duma, Margarita Peneva, Andrijana Gjorgjeska and Vesna Trajkova for their support and valuable input to our journal.

Toxic Epidermal Necrolysis: Case Report and Review BACKGROUND: Stevens–Johnson syndrome and toxic epidermal necrolysis (TEN) are severe mucocutaneous adverse drug reactions primarily caused by drugs. Characterized by fever, prodromal symptoms, and extensive epidermal sloughing with mucous membrane involvement (>90%), they are collectively termed e...

New Article of 2024 Now Available!
We are pleased to announce the release of a new article for 2024, titled “Botanical Larvicide from Jeruk Limau (Citrus amblycarpa) and Serai (Cymbopogon citratus) for Killing Aedes aegypti Larvae” .
We would like to extend our sincere appreciation to Refa Rahmaddiansyah, Eka Nofita and Sukarsi Rusti for their support and valuable input to our journal.

Botanical Larvicide from Jeruk Limau (Citrus amblycarpa) and Serai (Cymbopogon citratus) for Killing Aedes aegypti Larvae BACKGROUND: Dengue hemorrhagic fever is caused by the dengue virus which is transmitted through the bite of the Aedes aegypti mosquito which breeds in densely populated areas with humid and warm climates. The use of anti-mosquito drugs in the form of burns, sprays, lotions, or other forms has been w...

New Article of 2024 Now Available!
We are pleased to announce the release of a new article for 2024, titled “Ethylenediaminetetraacetic Acid-dependent Platelet Aggregation, Satellitism, and Phagocytosis in a Case in Which Aggregation was Resolved using Kanamycin Blood Collection Tubes”.
We would like to extend our sincere appreciation to Hiroki Doi, Yuri Seki, Katsuma Sakaizawa, Kaisei Ryu, Michiko Osawa, Seiko Sato, Hideaki Matsuura, Masato Hoshi, Hidehiko Akiyama and Hiroyasu Ito for their support and valuable input to our journal.

Ethylenediaminetetraacetic Acid-dependent Platelet Aggregation, Satellitism, and Phagocytosis in a Case in Which Aggregation was Resolved using Kanamycin Blood Collection Tubes BACKGROUND: This study aimed to investigate ethylenediaminetetraacetic acid (EDTA)-dependent pseudothrombocytopenia (EDTA-PTCP) a rare but significant phenomenon in clinical laboratories that cause diagnostic errors and unnecessary treatments. CASE PRESENTATION: Here, we present an 83-year-old male....

New Article of 2024 Now Available!
We are pleased to announce the release of a new article for 2024, titled “The Antioxidant and Antibacterial Effects of Gambier Catechin (Uncaria gambir Roxb) in Streptococcal Gingivitis: A Review”.
We would like to extend our sincere appreciation to Refa Rahmaddiansyah, Muhammad Zidan Amriza and Rauza Sukma Rita for their support and valuable input to our journal.

The Antioxidant and Antibacterial Effects of Gambier Catechin (Uncaria gambir Roxb) in Streptococcal Gingivitis: A Review BACKGROUND: Oral health is very important for general health and well-being. Oral diseases such as caries and periodontitis are common throughout the world. Periodontal is the main cause of tooth loss in adults. This disorder begins with gingivitis (swelling of the gums due to plaque), which, if lef...

New Article of 2024 Now Available!
We are pleased to announce the release of a new article for 2024, titled “Unlocking Therapeutic Potential of Bengkoang (Pachyrhizus erosus) Inulin and Lactobacillus Synergies in Synbiotics for Immunomodulatory Interventions in Indonesia: A Review”

We would like to extend our sincere appreciation to Refa Rahmaddiansyah, Rauza Sukma Rita and Sukarsi Rusti for their support and valuable input to our journal.

Unlocking Therapeutic Potential of Bengkoang (Pachyrhizus erosus) Inulin and Lactobacillus Synergies in Synbiotics for Immunomodulatory Interventions in Indonesia: A Review BACKGROUND: Indonesia’s vision for 2045 encapsulates a grand aspiration for global competitiveness and resilience, with an emphasis on cultivating robust and skilled human capital. This study delves into the pivotal role of health-centric food and beverages as a fundamental component aligned with ...

New Article of 2024 Now Available!
We are pleased to announce the release of a new article for 2024, titled “The Effect of Nutritional Status on the Quality of Life of People with HIV/AIDS (ODHA) Receiving Antiretroviral Therapy”.
We would like to extend our sincere appreciation to Riezky Nugroho and Erika Wardani for their support and valuable input to our journal.

The Effect of Nutritional Status on the Quality of Life of People with HIV/AIDS (ODHA) Receiving Antiretroviral Therapy BACKGROUND: Human immunodeficiency virus (HIV) is a type of virus that can weaken the immune system. People living with HIV (PLHIV) is vulnerable to a decrease in quality of life due to declining physical health and stigma from themselves and society. PLHIV is also found to have less intake, changes...

New Article of 2024 Now Available!
We are pleased to announce the release of a new article for 2024, titled “Prevalence and Characteristics of Allergic Asthma in a Sample of Dairy Farmers”.
The article is accessible to all members on our website and will also be co-published on Sciendo, expanding its reach.
We would like to extend our sincere appreciation to Sasho Stoleski, Jordan Minov, Dragan Mijakoski, Aneta Atanasovska, Dragana Bislimovska, Jovanka Karadzinska-Bislimovska and Kire Donovski for their support and valuable input to our journal.

Prevalence and Characteristics of Allergic Asthma in a Sample of Dairy Farmers AIM: The objective of the study is to evaluate the prevalence characteristics of allergic asthma in a sample of dairy farmers. METHODS: We performed a cross-sectional study including 83 dairy farmers (mean age: 52.6 ± 8.7 years; mean exposure duration: 23.7 ± 7.6 years) compared to 80 office contr...

New Article of 2024 Now Available!
We are pleased to announce the release of a new article for 2024, titled “CAR-T Cells – Main Steps for Obtaining a Proper “Live Drug” Adoptive Therapy”.
The article is accessible to all members on our website and will also be co-published on Sciendo, expanding its reach.
We would like to extend our sincere appreciation to Monica Neagu and Carolina Constantin for their support and valuable input to our journal.

CAR-T Cells – Main Steps for Obtaining a Proper “Live Drug” Adoptive Therapy Chimaeric antigen receptor (CAR) T lymphocytes (CAR-T) discovered in 1992 have been in the recent years in the spotlight of both researchers and clinicians. Immune therapy with engineered CAR-T cells has been approved by the FDA since 2017 for pediatric and young adult acute lymphoblastic leukemia.....

New Article of 2024 Now Available!
We are pleased to announce the release of a new article for 2024, titled “Drug Rash with Eosinophilia and Systemic Symptoms Syndrome: Case Report and Literature Review”.
The article is accessible to all members on our website and will also be co-published on Sciendo, expanding its reach.
We would like to extend our sincere appreciation to Silvija Duma, Suzana Nikolovska, Hristian Duma, Hristina Breshkovska, Ivana Dohcheva Karajovanov, MajaDimova and Ana Trpeska-Boshoska for their support and valuable input to our journal.

Drug Rash with Eosinophilia and Systemic Symptoms Syndrome: Case Report and Literature Review BACKGROUND: Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome is a rare, potentially life-threatening, drug-induced hypersensitivity reaction. This condition is characterized by a range of symptoms, including cutaneous reaction, hematologic abnormalities, lymphadenopathy, and po...

New Article of 2024 Now Available!
We are pleased to announce the release of a new article for 2024, titled “Deviation in White Blood Cell Count Measurement between WNR and WDF Channels on an Automated Hematology Analyzer XN-3000: A Case Report”.
We would like to extend our sincere appreciation to Hiroki Doi, Hideaki Matsuura, Hidehiko Akiyama and Hiroyasu Ito for their support and valuable input to our journal.

Deviation in White Blood Cell Count Measurement between WNR and WDF Channels on an Automated Hematology Analyzer XN-3000: A Case Report BACKGROUND: At present, complete blood count (CBC) testing is one of the most common clinical tests. The XN-3000 used in our hospital utilizes the principles of impedance and semiconductor laser flow cytometry, which contains two types of leukocyte fractionation methods: White cell nucleated (WNR) a...

New Article of 2023 Now Available!
We would like to extend our sincere appreciation to Naina Mohamed Pakkir Maideen for the support and valuable input to our journal.

Efficacy of Nilavembu Kudineer for Dengue Fever Management – An Overview of Clinical and Preclinical Evidences BACKGROUND AND AIM: Dengue viral disease (DVD) is a tropical arboviral disease that is caused by dengue virus (DENV), which is transmitted mainly by the bite of female Aedes aegypti mosquitoes. No specific antiviral drug is approved yet to manage the patients with DENV infection, who are managed usi...

New Article of 2023 Now Available!
We would like to extend our sincere appreciation to the Alaa A. Rashad, Manal F. Elshamaa, Doaa M. Salah, Maha Rasheed, Nagwa Kantosh, Rasha Nazieh, Mervat Ismail, Ashraf S. Kamel and Shaimaa Sayed for their support and valuable input to our journal.

Assessment of Serum Soluble CD30 Levels in Pediatric Kidney Transplant Recipients BACKGROUND: CD30 is considered to be a marker for the activated immune system; however, its association with acute rejection and kidney graft function showed severe heterogeneity. AIM: The aim of this study is to examine the predictive value of soluble CD30 (sCD30) levels for kidney transplantation....

БАРАМЕ ГЛАВЕН И ОДГОВОРЕН УРЕДНИК НА South East European Journal of Human Genetics
Одлучивме да го активираме списанието South East European Journal of Human Genetics од почетокот на 2024 година (https://www.id-press.eu/seejhg/management/settings/context). Потребни ни се Главен и одговорен уредник, заменик уредник, секретар и членови на Уредувачкиот одбор. Пожелно е да се граѓани од Република Македонија.
Услови:
- Докорска теза од областа на хумана генетика;
- Регистрација во ORCID;
- Хиршов индекс (H-Index) во Google Scholar над 10 за Главен и одговорен уредник, и над 5 за останатите.
За 2024 година функциите се волонтерски.
Потребно е да се достави Мотивациско писмо, биографија, ORCID iD и една слика во боја (*jpg format) до [email protected]
Со среќа,
Поздрав,
Проф. д-р Мирко Спироски,
Научна фондација СПИРОСКИ

New Publication Alert: New Article of 2023 Now Available
We would like to extend our sincere appreciation to the Margarita Prifti-Kurti, Genc Sulcebe and Zamira Yll for their support and valuable input to our journal.

The Diagnostic Value of ANA and Anti-SMA in Suspected Patients with Autoimmune Hepatitis BACKGROUND: Autoimmune hepatitis (AIH) is an unknown chronic disease characterized by hepatocellular inflammation with a tendency to progress to cirrhosis. AIH can present with symptoms of acute hepatitis with symptoms of chronic liver disease. AIH occurs globally; it is more commonly found in femal...

New Article of 2023 Now Available!
We would like to extend our sincere appreciation to the authors Refa Rahmaddiansyah, Wahida Rahmi and Rauza Sukma Rita for their support and valuable input to our journal.

Anti-inflammatory Effect of Gambier Catechin (Uncaria gambir Roxb) on Rheumatoid Arthritis: A Review BACKGROUND: Rheumatoid arthritis (RA) is a chronic inflammatory disease of the joints and varies in severity in patients. Inflammation in the joints causes high levels of systemic pro-inflammatory cytokines such as interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) which have an impact on pe...

New Article of 2023 Now Available!
We would like to extend our sincere appreciation to the authors Valentina Risteska-Nejasmic and Dragan Gjorgjievski for their support and valuable input to our journal.

Acute Bronchiolitis and Other Predictors for Early Diagnosis of Childhood Asthma BACKGROUND: Early onset of acute bronchiolitis is associated with early onset of childhood asthma. Unfortunately, childhood asthma tends to be frequently overlooked and not optimally managed. Family pediatricians, however, possess an exceptional opportunity to recognize the connection of these condi...

New Article of 2023 Now Available!
We would like to extend our sincere appreciation to the authors Natasha Stojkovska, Nevena Manevska, Tanja Makazlieva and Sinisha Stojanoski for their support and valuable input to our journal.

Levels of Antithyroid Antiperoxidase and Antithyroglobulin Antibodies in Patients with Graves Hyperthyroidism – Predictors of Initial and Sustained Remission and Consecutive Hypothyroidism BACKGROUND: Initial and sustained remission is the principal objective in patients with Graves hyperthyroidism (GH) treated with antithyroid drugs (ATD). AIMS: Our study aimed to investigate the predictive value of antithyroid antiperoxidase (aTPO) and antithyroglobulin (aTg) levels on initial and s...

New Article of 2023 Now Available!
We would like to extend our sincere appreciation to the author Wafaa M. Abdelghany for the support and valuable input to our journal!

View of Acquired Postpartum Hemophilia A Presentation of Severe Hematuria: A Case Report

New Article of 2023 Now Available!
We would like to extend our sincere appreciation to the authors Mariya Ivanovska, Meral Naimova and Marianna Murdjeva, for their support and valuable input to our journal.

Effects of Stress on the Brain’s Glymphatic System Psychoneuroendocrine immunology is an integrated field that explores the pathways through which psychological experiences influence immune function and how the immune system, in turn, might alter brain function. The glial-lymphatic system regulates fluid balance and waste removal in the central nerv...

New Article of 2023 Now Available!
We would like to extend our sincere appreciation to the authors Aneta Terzievska, Daniela Veleska-Stevkovska, Gordana Apostolova, Zaklina Mencheva and Stavre Trajculeski, for their support and valuable input to our journal.

The Effectiveness of the Influence of the Second Generation Platelet-rich Fibrin in the Treatment of Localized Individual Miller I and II Gingival Recessions (Case Report) BACKGROUND: The mucogingival surgical modality subepithelial connective tissue graft (SCTG) and the coronally positioned flap (CAF) in the treatment of Miller I and II gingival recessions are considered “gold standard,” that is, a technique for predictable and complete gingival root coverage def...

New Article of 2023 Now Available!
We would like to extend our sincere appreciations to the authors, Amirsaleh Abdollahi, Rouzbeh Kadkhodaee, Armaghan Kazeminejad, Lotfollah Davoodi, Muhammadreza Oraee Karimi, Alireza Razavi and Sobhan Mohebbi Najmaba, for their support and valuable input to our journal!

Topical Formulation Based on Arnebia euchroma as a Novel Possible Efficient Treatment on Epidermolysis Bullosa Lesions: A Case Series of Fourteen Patients BACKGROUND: Epidermolysis bullosa (EB) is a skin fragility disorder that results in the disruption of the dermo-epidermal junction and painful blisters on the skin and mucous membranes. Currently, there is almost no definite treatment for EB patients. AIM: This study aims to assess the effect of top...

New Article of 2023 Now Available!
We would like to extend our sincere appreciations to the authors, Jordan Minov, Sasho Stoleski, Dragan Mijakoski, Aneta Atanasovska, Maja Panajotovic-Radevska and Dragana Bislimovska, for their support and valuable input to our journal!

Incidence of Immunological Occupational Asthma in 2015–2022 by Occupation: Macedonian Experience BACKGROUND: Immunologic occupational asthma (OA), a more prevalent OA type than non-immunologic OA, became an important public health problem in the last decades worldwide. AIM: To present the distribution of new diagnosed cases of immunologic OA in the RN Macedonia in the period 2015–2022 by occu...

First Article of 2023 Now Available!!!
"Systemic Circulating Leptin – Aiding New Dimension of Immune-Related Skin Carcinogenesis and Lipid Metabolism”
I would like to express my personal gratitude to the authors, Monica Neagu, Mihaela Surce, and Carolina Constantin, for their support and valuable contribution to our journal.

Vol. 6 No. 1 (2023): SEE J Immunol | South East European Journal of Immunology (SEEJIM) New Editor-in-Chief for South East European Journal of Immunology (SEEJIM) February 2, 2023 Dear SEEJIM members, I am very proud to announce that Slavica Hristomanova-Mitkovska, MD, MSc. has been appointed as the new Editor-in-Chief for South East European Journal of Immunology (SEEJIM).

Recruitment of Marrow Donors in the Non-governmental Sector of the Republic of North Macedonia, 2022
Ana Vučurević, Ivo Spiroski, Emilija Andonoska, Katerina Spiroska, Teodora Fildishevska, Mirko Spiroski*
Scientific Foundation SPIROSKI, Skopje, Republic of North Macedonia

Recruitment of Marrow Donors in the Non-governmental Sector of the Republic of North Macedonia, 2022 BACKGROUND: Bone marrow transplantation is a well-established lifesaving treatment procedure for many patients with various diseases, such as blood cell cancers (leukemia), some severe hematological diseases (aplastic anemia) and some rare diseases, as well as immune deficiency disorders. Allogeneic...

The South East European Journal of Immunology (SEEJIM) is a top-tier open access medical science journal published by the Scientific Foundation SPIROSKI. It is a modern journal covering all areas of the immunological sciences (sections), from basic and clinical immunology to immunogenetics and allergology in several categories (editorial, original papers, professional papers, conference papers, invite papers, case reports, and review papers). The journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. SEEJIM is published continuously online.