Breann Robinson, Stylist

Smash SMARD is proud to make the most exciting announcement yet- that the first ever therapy for IGHMBP2-related disorders has been granted approval for a clinical trial to begin .

In 2018, smashSMARD and smashsmard.de approached Kathrin Meyer’s Lab at Nationwide Children's Hospital to lead pre-clinical research and development of a clinical grade gene therapy for IGHMBP2-related disorders. Almost 3 years to the day, we are beyond hopeful to share this news.

We are pleased that the U.S. Food and Drug Administration recognizes the significant unmet need for treatments for IGHMBP2-related disorders, including SMARD1 and CMT2S. In October 2021, the FDA cleared the Investigational New Drug (IND) application which allows a clinical trial to begin.

This announcement would not be possible without the collaboration from Gregory Cox at The Jackson Laboratory, Dr. Burghes’ Lab and Dr. Arnold’s Lab at The Ohio State University, and Dr. Corti Lab at Associazione Centro Dino Ferrari. Additionally, thank you to Andelyn Biosciences for timely clinical product development. The FDA played an instrumental role in allowing this program to move forward at lightning speed. Lastly, thank you to the principal investigator and treating physician, Dr. Megan Waldrop at Nationwide Children’s Hospital for your commitment to our community.

In Alcyone Therapeutics Inc., we found a steadfast partner who is funding the clinical trial in addition to significant preclinical development funding including chemistry, manufacturing and control. Their support was not limited to funding but included non-monetary support pertinent to the clinical development.

Thank you most importantly to our tens of thousands of donors who have believed in our cause, the families impacted by this disease. Without you, this treatment and announcement would not exist. https://clinicaltrials.gov/ct2/show/NCT05152823?cond=ighmbp2&draw=2&rank=1

Breann Robinson (breann.stylist) on about.me

Who do you know that has hair in need of some updating, Breann-style? Send them in! I love new clients, and I reward those who refer to me with $10 off of their next service.

about.me I have been a professional stylist and colorist for over eleven years, and have enjoyed building a solid and loyal following in the 50th and France area of Edin

Welcome to Julia Bretey Salon

I'm so excited to be back in the 50th and France area of Edina! Back in my old stomping grounds! I absolutely love my new digs: The Julia Bretey Salon

juliabreteysalon.com