ScheuringLab

Hey folks at
We got a lot of interesting stuff for you this year!

Change the scale bar and the black hole becomes a protein imaged by AFM! ;)

For the first time, you can see what a black hole looks like Global telescope consortium images supermassive black hole ringed by bright gas

Our latest review on using high-speed AFM to study the dynamics of channels and transporters out today: https://authors.elsevier.com/c/1YjVF,LqArC4yO

Advances in high-speed atomic force microscopy (HS-AFM) reveal dynamics of transmembrane channels and transporters Recent advances in high-speed atomic force microscopy (HS-AFM) have made it possible to study the conformational dynamics of single unlabeled transmem…

Hey early birds, we hope to see you in the BPS morning sessions where Yi-Chih and a bit later George are talking about their latest results on the Piezo Channel and HS-AFM hight spectroscopy and CLC channels!

Are you at the Biophysical Society Meeting in Baltimore? Many of the Scheuring Lab are too! Today Fang is presenting his work on Septins during the Poster Session at 1:45pm at stand B348. Pass by an have a look!

Simon is opening the "Established Investigator" Seminar Series at Weill Cornell demonstrating the power of HS-AFM to study membrane proteins!

Happy birthday, Fang! We hope you like your new Spurs outfit and we look forward to seeing you at the basketball court with it!

Our recent work highlighted in Nature Methods!
https://rdcu.be/bd4cy

AFM in a split second A new development in high-speed atomic force microscopy enables microsecond resolution.

After 10 hours of high-end high-speed AFM data presentations we go now over to our potluck AFM holiday party and are looking to Secret Santa to come!

The Bio-AFM & Friends Crew at yesterday's WCM Holiday Party! We had a blast!

Beautiful work that pushes the speed limits of AFM even further! Congratulations! https://www.nature.com/articles/s41467-018-07512-3.epdf?shared_access_token=ShQU1d1LHFp9_7i1vLT-VtRgN0jAjWel9jnR3ZoTv0NncKzCc4rIZOrhIi2btxmD8lrM6C3CkaW8TstmueVONk90q_SylTamvt3hAADv6cmVJ_Bnk-Ca_z-5OoKaxjU41rwtG1Jo2Ut4ZK4leysUANbhTwxaePcmTGVUAwSnjmA%3D

High-speed AFM height spectroscopy reveals µs-dynamics of unlabeled biomolecules The dynamics of biomolecules can occur over a wide range of time and length scales. Here the authors develop a high-speed AFM height spectroscopy method to directly detect the motion of unlabeled molecules at Angstrom spatial and microsecond temporal resolution.

We are expecting a very special AFM member! Yesterday we gathered together to celebrate the soon arrival of baby girl Heath. 👶 Bets for delivery date are still open ^^

Congratulations to Yi and co-authors for this beautiful study on the GLIC channel! http://www.pnas.org/content/early/2018/08/31/1805621115

Structural titration of receptor ion channel GLIC gating by HS-AFM Gloeobacter violaceus ligand-gated ion channel (GLIC) is a proton-gated, cation-selective channel, a Cys-loop family member of the pentameric ligand-gated ion channels (pLGICs). In a pursuit to provide evidence of function-related conformational changes of a pLGIC in membrane, at ambient temperature...

Arsenal has a new player!.... They just don't know it yet!

Congratulation to Atsushi and his improved amplitude detection method! https://aip.scitation.org/doi/figure/10.1063/1.5038095

A novel phase-shift-based amplitude detector for a high-speed atomic force microscope In any atomic force microscope operated in amplitude modulation mode, aka “tapping mode” or “oscillating mode,” the most crucial operation is the detection of the cantilever oscillation amplitude. Indeed, it is the change in the cantilever oscillation amplitude that drives the feedback loop,...

Atsushi’s new toy! https://t.co/vARI9shUt9

Scheuring Lab on Twitter “Atsushi’s new toy! https://t.co/vARI9shUt9”

Happy birthday, Atsushi! Have fun with your new toy! We could guess from your reaction that we picked the right thing!

Yesterdays Lab excursions to NJ! Thank you so much for the delicious BBQ and that great Sunday afternoon, Yi-Chih!

Happy birthday, Tina! Have fun with your new running gear and we hope it helps to get rid of the Gugelhupf! ^^

Congratulation, Grigory! Good job! https://www.facebook.com/photo.php?fbid=1704732292941772&set=a.1704732282941773.1073741826.100002150526537&type=3&theater

Happy birthday, Yi-Chih! Have a great day!

Yesterday was all about the team! 1st Escape game session of the Bio-AFM Lab and it will not be the last one! Thank you, Escape Games NYC! It was marvelous!

Happy birthday, Juca! We hope you will get at least as nice Snf7 assemblies as the cinnamon rolls forming the cake! All the best and have fun with potting the balls! :)

May the forth be with you and trigger nice protein purifications, membrane reconstitutions, super sharp cantilever tips, and image resolutions at the limits! https://www.youtube.com/edit?o=U&video_id=1Zbhl4VxSHE

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Exciting and fun ping pong tournament yesterday at fat cat. The winner was Simon. Again. ;p

Bio-AFM-Lab table tennis tournament!
Atsushi and Yi-Chih reach the semifinals! https://t.co/MWvGWt7MuD

Scheuring Lab on Twitter “Bio-AFM-Lab table tennis tournament! Atsushi and Yi-Chih reach the semifinals! https://t.co/MWvGWt7MuD”

Yesterdays women's day celebration with cake and ice cream! Also the guys got a piece 😉

Happy birthday, Hiro! Hope you will see many home-runs at the game! ⚾️🍻🎉