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https://abgenex.com/webinars/Webinar-Nanobodies.php

Abgenex Pvt. Ltd. is inviting you to a scheduled Zoom meeting.

Time: Sep 26, 2023 11:30AM IST (GMT + 5.30 Hours)

Join Zoom Meeting
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Meeting ID: 962 6637 7276
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https://abgenex.com/webinars/Webinar-Nanobodies.php

Derived from sharks and camelids, nanobodies are compact antibody fragments with exceptional potential. The webinar explores their precise targeting capabilities, enabling the unraveling of complex biological pathways and the development of targeted therapies. The outstanding stability of nanobodies makes them ideal for diagnostics, therapeutics, and biochemical assays. Join us to unlock the power of nanobodies and discover their transformative impact on scientific innovation.

New Year Wishes From Abgenex
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Abgenex offers 20% special discount on the Research Grade Biosimilar Products!
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Epitope Design & Peptide Synthesis
As an innovative antibody and reagent supplier company ABGENEX provides a full range of custom antibody services for the life science & Biomedical industry. With over twelve years of antibody experience our scientists have the skills and tools necessary to help you at every step of the process, from antigen design to antibody production and validation.

https://abgenex.com/custom-monoclonal-antibody-development-production-service-in-india

ABGENEX develops and commercializes novel reagents suitable for research in human biology in general and disease processes in particular in India. We are a leading custom monoclonal antibody developing company in India. Availability of newer reagents paves the way for development of new diagnostic assays and helps in finding potential therapies for such diseases. We possess the capacity to develop more than 400 polyclonal and 100 monoclonal antibodies per year in India (with application validated in different test systems) through our in-house R&D as well as from scientific collaborations in India and abroad.

New Monkeypox Reagents Released

Monkeypox (MPX), a double-stranded DNA virus, is a zoonotic orthopoxvirus belonging to the family Poxviridae that causes disease in humans similar to smallpox with notably lower mortality. MPX is endemic to western and central Africa, with outbreaks in the Western Hemisphere associated with the exotic pet trade and international travel. The monkeypox virus or MPXV is extremely pathogenic and can spread both from animals to humans and from human to human.
As of August 9, 2022, 31,800 monkeypox cases have been reported in at least 89 territories globally -- the vast majority in places where the virus is non-endemic, according to the US Centers for Disease Control and Prevention (CDC). This is the first time that so many monkeypox cases have been reported in non-endemic and endemic countries in the world. The World Health Organization (WHO) has declared Monkeypox as Global health emergency. Abeomics has developed a line of products that would help in monkeypox research.

Polyclonal antibody to ASK1
Ask1 (apoptosis signal-regulating kinase 1), a serine/threonine kinase, is a member of the MAPKKK family that constitutes the JNK and p38 (MAPK) cascades. Members of this family are activated by physiological and cytotoxic stresses and induce various stress responses including apoptosis. Specifically, Ask1-MAPK cascades have been shown to be involved in endoplasmic reticululum (ER) stress-induced apoptosis and in neuronal cell death. Studies suggest that ER stress-induced apoptosis plays critical roles in the pathogenesis in some neurodegenerative diseases including Alzheimer's, Parkinson's, polyglutamine (polyQ), amyotrophic lateral sclerosis (ALS) and Prion diseases. However, the regulation and function of Ask1 in neuronal cell death remains to be fully elucidated. In addition to playing a role in ER stress-induced apoptosis, Ask1 is also thought to be important in cytokine-induced apoptosis, and may also have functions other than apoptosis including roles in cell survival and differentiation. Structurally, human Ask1 has a serine/threonine kinase domain in the middle of the molecule. The kinase domain is evolutionarily conserved from nematode to human. A threonine residue with the activation loop of the kinases domain (Thr838 of human Ask1) is essential for Ask1 activation. There are two coiled-coil domains, one in the N-terminal and the other in the C-terminal domain. The coiled-coil domain in the C-terminal domain has been shown to be required for homo-oligomerzation.

For more details visit our website - : http://abgenex.com and follow the web-page : https://abgenex.com/polyclonal-antibody-to-ask1