Medical Dermatology Associates of Chicago

https://www.everydayhealth.com/eczema/products-to-stop-using-asap-if-you-have-atopic-dermatitis/

Atopic Dermatitis: 7 Products That Might Do More Harm Than Good Here’s why experts suggest you skip essential oils and chemical sunscreens if you have this common type of eczema.

I'm excited to share our recent paper "Impact of atopic dermatitis lesion locations and extent on patient burden: A real‐world study."

What do the study results mean?
"AD impacts all body areas. Greater number of lesion locations are related to more severe disease and poor disease control. Regardless of number of lesion locations, patients experience substantial disease burden and need effective therapies to manage AD."


Reference: Simpson E, Lio P, Pierce E, Cronin A, McLean RR, Eckmann T, Atwater AR, Dawson Z, Silverberg JI. Impact of atopic dermatitis lesion locations and extent on patient burden: A real‐world study. JEADV Clinical Practice. 2024.

JEADV Clinical Practice | Clinical Dermatology and Venereology Journal | Wiley Online Library In this real-world study in patients with atopic dermatitis (AD), majority of the patients had lesions in ≥4 locations. Greater number of lesion locations correlated with severe disease burden, poor ...

A brief write-up of our recent article on complementary and alternative therapies for scarring alopecias!

Complementary and Alternative Therapies for Scarring Alopecia: What Does the Evidence Show? - The Dermatology Digest There are no U.S. Food and Drug Administration (FDA)-approved therapies for scarring alopecia, and existing treatments are often ineffective, which is why many patients turn to complementary and alternative therapies. Unfortunately, there is an extremely limited body of evidence on these therapies,....

I'm excited to share our recent paper "Complementary and Alternative Therapies for Scarring Alopecia." This is a tough set of conditions and there are some fascinating signals for unconventional approaches.

Ref: Lio P, Venkatesh T. Complementary and Alternative Therapies for Scarring Alopecia.
Journal of Integrative Dermatology. Published online August 27, 2024.

Full paper here: https://www.jintegrativederm.org/article/122502-complementary-and-alternative-therapies-for-scarring-alopecia

Key table:

I am excited to share our recent updated systematic review on alternative treatments for psoriasis.




Ref: Chalupczak NV, Lio PA Complementary and Alternative Therapies for Psoriasis. Arch Dermatol Res 316, 531 (2024). https://doi.org/10.1007/s00403-024-03279-4

Key highlight:

Excited to share our recent paper on turmeric and vitiligo! https://thedermdigest.com/turmeric-and-associated-curcuminoids-in-the-treatment-of-vitiligo/

Ref: Butler D, Lio P. Exploring Turmeric and Associated Curcuminoids in the Treatment of Vitiligo. The Dermatology Digest. 2024 August 8.

Exploring Turmeric and Associated Curcuminoids in the Treatment of Vitiligo - The Dermatology Digest By Dominique Butler and Peter Lio, MD Introduction Vitiligo is a multifaceted skin disorder, characterized by the loss of pigment in affected regions of the skin, via a gradual decrease in melanocytes1. Exhibiting a hallmark lesion that is amelanotic, chalk-white, and non-scaly, the disorder commonl...

Super fun discussion with Jennifer Fugo, CNS about gluten and the skin!

Dermatitis Herpetiformis Explained (Itchy Gluten-Triggered Celiac Skin Rash) | Dr. Peter Lio SUBSCRIBE for weekly episodes + more: https://bit.ly/356al6G Complete transcript + original post: www.skinterrupt.com/352Get help: https://www.skinterrupt.co...

Excited to share a brief piece about topical hypochlorous acid and topical endolysins as antibacterial agents in dermatology: https://jdnppa.com/jdnppa-original-research-the-future-of-topical-antibiotics-in-dermatology/

JDNPPA Original Research: The Future of Topical Antibiotics in Dermatology - JDNPPA By Kripa Ahuja, MS, and Peter Lio MD Introduction Antibiotics have drastically changed the medical landscape since the discovery of penicillin in the early 1920s. In the ensuing years, research into antibiotics flourished. Today, they are considered critical components of the therapeutic armamentari...

Really neat article about food and eczema! National Eczema Association

https://www.webmd.com/skin-problems-and-treatments/eczema/news/20240711/cm/which-comes-first-eczema-or-food-allergies

Which Comes First: Your Eczema or Your Food Allergies? Though studies have shown a clear link between dermatitis and food allergies, controversy abounds over which comes first – atopic dermatitis or the food allergy.

I'm very excited to share our recent paper: Combining treat-to-target principles and shared decision-making: International expert consensus-based recommendations with a novel concept for minimal disease activity criteria in atopic dermatitis!

Big idea: Better treatments for eczema go hand in hand with setting higher treatment targets, thus steadily increasing the standard of care.

Ref: Silverberg JI, Gooderham M, Katoh N, Aoki V, ...Lio P, et al. Combining treat-to-target principles and shared decision-making: International expert consensus-based recommendations with a novel concept for minimal disease activity criteria in atopic dermatitis. J Eur Acad Dermatol Venereol. 2024; 00: 1–10. https://doi.org/10.1111/jdv.20229



Key Table:

I'm excited to share our recent review about external and environmental factors and their role in causing eczema.

Ref: Zhang Q, Lio P. Assault on the Skin: A Review of External Factors that Damage the Skin Barrier and Microbiome. The Dermatology Digest. 2024 June; 24-28. https://tdd.mydigitalpublication.com/june-2024/page-24



Key Table:

I'm excited to share our recent paper: "Postbiotics and Atopic Dermatitis: Aiming to Modulate the Gut-Skin Axis." There is a lot going on in this domain!

Ref: Paz M, Lio P. Postbiotics and Atopic Dermatitis: Aiming to Modulate the Gut-Skin Axis. Journal of Integrative Dermatology. Published online June 25, 2024.

Full paper here: https://www.jintegrativederm.org/article/120208-postbiotics-and-atopic-dermatitis-aiming-to-modulate-the-gut-skin-axis



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I am excited to share our recent paper, "Lebrikizumab Improves Quality of Life and Patient-Reported Symptoms of Anxiety and Depression in Patients with Moderate-to-Severe Atopic Dermatitis."

Ref: Lio PA, Armstrong A, Gutermuth J, et al. Lebrikizumab Improves Quality of Life and Patient-Reported Symptoms of Anxiety and Depression in Patients with Moderate-to-Severe Atopic Dermatitis. Dermatol Ther (Heidelb) (2024). https://doi.org/10.1007/s13555-024-01199-9



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I'm excited to share our recent clinical update on epidermolysis bullosa.

Full Reference:

Griffith M, and Lio P. Epidermolysis Bullosa: A Clinical Review and Update. The Dermatology Digest. Published online May 21, 2024.
https://thedermdigest.com/epidermolysis-bullosa-a-clinical-review-and-update/

Key Figure:

A super fun discussion with the amazing Dr. Rob Sidbury about the new atopic dermatitis guidelines and how they differ beween Dermatology and Allergy! https://practicaldermatology.com/series/practical-dermatology-journal-club-atopic-dermatitis/journal-club-comparing-recommendations-from-different-ad-guidelines/24466/

Journal Club: Comparing Recommendations from Different AD Guidelines Peter Lio, MD, talks with Robert Sidbury, MD, MPH, a pediatric dermatologist at Seattle Children's Hospital, about some of the differences in recommendations from the Annals of Allergy, Asthma, and Immunology Joint Task Force AD guidelines, and the Journal of the American Academy of Dermatology (JAA...

Excited to share our recent paper: "Improving systemic therapy selection for inflammatory skin diseases: A clinical need survey"

Ref: Brownstone ND, Farberg AS, Litchman GH, Quick AP, Siegel JJ, Hurton LV, Goldberg MS, Lio PA. Improving Systemic Therapy Selection for Inflammatory Skin Diseases: A Clinical Need Survey. JAAD International. 2024 Apr 6.



Summary and key table:

I'm excited to share our recent paper "Impact of atopic dermatitis lesion locations and extent on patient burden". There are some neat findings in here, I think.

Conclusion:"In our cohort of real‐world patients with AD, lesions were most often present on the arms and lower limbs, and more than half of the patients reported ≥4 areas with AD lesions. An increase in the number of lesion locations corresponded with severe disease burden and poor disease control."

Ref: Simpson E, Lio P, Pierce E, Cronin A, McLean RR, Eckmann T, et al. Impact of atopic dermatitis lesion locations and extent on patient burden: a real-world study. JEADV Clin Pract. 2024; 1–15. https://doi.org/10.1002/jvc2.413

Key Figure:

Such a pleasure to talk with the amazing dermatologist Walter J. Liszewski, MD about TSW today! We got into some of the big questions that must be tackled about this terrible conditoin.

https://www.vumedi.com/video/topical-steroid-withdrawal-separating-fact-from-fiction/

Kelly Barta

Very excited to share our recent paper about music and the skin!

Ref: Zhang Q, Lio P. Maladies and Melodies of the Skin: Exploring Music’s Role in Causing and Improving Cutaneous Disease. The Dermatology Digest. Published online April 19, 2024.

Full paper here: https://thedermdigest.com/maladies-and-melodies-of-the-skin-exploring-musics-role-in-causing-and-improving-cutaneous-disease/

A portion of one of the tables:

Excited to share a new video series: Dermatology Times Expert Perspectives on atopic dermatitis!



https://www.dermatologytimes.com/expert-perspectives/advancements-in-atopic-dermatitis-insights-from-the-2024-masterclasses-in-dermatology-conference

¡Estoy realmente emocionado y honrado de presentar sobre Dermatología Integrativa en este próximo congreso! La Dermatología Integrativa va más allá de lo convencional, enfocándose en la raíz de las enfermedades y considerando al paciente en su totalidad. Esta práctica combina tratamientos tradicionales con enfoques complementarios, promoviendo un estilo de vida saludable y el uso de terapias no convencionales ¡Espero verlos allí y compartir sobre este apasionante tema!

(I am really excited and honored to be presenting on Integrative Dermatology at this upcoming conference! Integrative Dermatology goes beyond conventional treatments, focusing on the root causes of diseases and considering the patient as a whole. This practice combines traditional treatments with complementary approaches, promoting a healthy lifestyle and the use of unconventional therapies. I look forward to seeing you there and sharing about this fascinating topic!)

Congreso Asocolderma Para hablar de la dermatología integrativa, primero debemos explicar qué es la Medicina Integrativa. Esta novedosa rama de las ciencias de la salud es la que busca soluciones más allá de la medicina convencional, la que se enfoca en la raíz de las enfermedades teniendo en cuenta al paciente en ...

Discussing the new atopic dermatitis guidelines:

https://practicaldermatology.com/series/practical-dermatology-journal-club-atopic-dermatitis/atopic-derm-journal-club-ad-guidelines-may-represent-a-paradigm-shift-in-care

Excited to share our recent paper: "Transcutaneous Sensitization: The Real Skinny on Food-based Emollients and Skincare Products."

This came about from some insightful clinical questions: given that we know you can develop allergies from food antigens going through damaged skin, where does that leave moisturizers that have foods like oatmeal and coconut in them?

Key point:
"Coconut, wheat, sunflower, and oat-based products are commonly recommended for patients with compromised skin. Given that the risk of transcutaneous sensitization from these food-based or food-derived products is clinically very low, providers should feel comfortable suggesting these products to patients outside of those with existing allergies to the ingredients."

Full paper: https://thedermdigest.com/transcutaneous-sensitization-the-real-skinny-on-food-based-emollients-and-skincare-products/

Ref:
Lohray R, and Lio PA. Transcutaneous Sensitization: The Real Skinny on Food-based Emollients and Skincare Products. The Dermatology Digest. Published online March 14, 2024. https://thedermdigest.com/transcutaneous-sensitization-the-real-skinny-on-food-based-emollients-and-skincare-products/

Transcutaneous Sensitization: The Real Skinny on Food-based Emollients and Skincare Products - The Dermatology Digest By Rishabh Lohray, BS, and Peter A. Lio, MD Introduction The introduction of food proteins into the gastrointestinal tract early in life has been shown to induce tolerance and thus decrease the incidence of at least some food allergies. At the same time, there is convincing evidence that transcutane...

Excited to share our recent paper about the order of application for a topical steroid and a moisturizer! It's a weird question that comes up frequently, and the answer is a bit more complex than we had anticipated...

Full reference: Ahuja, K., Lio, P.A. Topical steroids or emollients: does order matter?. Arch Dermatol Res 316, 104 (2024).

Topical steroids or emollients: does order matter? - Archives of Dermatological Research Topical corticosteroids, topical steroid-sparing agents, and emollients are all used to treat atopic dermatitis. However, there are no formal guidelines dictating the order and timing in which these topical modalities should be applied. Additionally, the order of application may change drug absorpti...

Very excited to share our recent paper doing a deep dive on the new atopic dermatitis guidelines!

Osher GR, Chu D, and Lio P. Inside the New AAAAI/ACAAI Joint Task Force Guidelines on Managing AD. The Dermatology Digest. 2024 March; 22-27.



Full article here:

The Dermatology Digest March 2024 Page 22 Inside the New AAAAI/ACAAI Joint Task Force Guidelines on Managing AD N ew atopic dermatitis therapies are changing the way this disease is treated. By Gabrielle Rose Osher, Derek Chu, MD, PhD, and Peter Lio, MD Introduction Following a prolonged period of little progress, there has been a surge in....

Very excited to share our recent paper "Alternative and Complementary Therapies for Vitiligo".

Full article here: https://tdd.mydigitalpublication.com/publication/?m=71606&i=817504&p=52&ver=html5

The Dermatology Digest March 2024 Page 50 THE IRREGULAR BORDER VITILIGO Alternative and Complementary Therapies for Vitiligo: A NARRATIVE REVIEW By Michelle Megan Kwan and Peter Lio, MD Introduction Vitiligo is an autoimmune skin disorder characterized by depigmented patches of skin, caused by the destruction of melanocytes. 1 It has an est...

Very excited to share our recent paper on using ceramide-containing skin care for atopic dermatitis.

It is freely available here: https://jddonline.com/articles/attenuation-of-atopic-dermatitis-in-newborns-infants-and-children-with-prescription-treatment-and-ceramide-containing-skin-care-a-systematic-literature-review-and-consensus-S1545961624P0152X

Key table:

Super neat new video from the National Eczema Association:

From the Desk of Dr. Peter Lio: The Truth About Diet and Eczema On this episode of From the Desk of, Dr. Peter Lio discusses diet and eczema, including how researchers have uncovered a new understanding about the connecti...

Very excited to share a new educational program about JAK inhibitors: Optimizing Outcomes in Immunologic Disease: The Role of JAK Inhibitors in the Paradigm of Patient Care!

Learning Nexus: https://www.medscape.org/immunologynexus/

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Excited to share our recent paper on a 3-step over-the-counter approach to treating eczema: https://jddonline.com/articles/individual-article-a-novel-3-step-over-the-counter-eczema-regimen-improves-eczema-severity-itch-and-life-quality-randomized-study-S1545961623SSF388641s21X/?_page=4