Xylyx Bio, Inc.

Xylyx Bio offers tissue-specific ECM substrates, clinically relevant data packages, and compound tes

Xylyx Bio's mission is to increase predictiveness and confidence in drug discovery for cancer, fibrosis, and other devastating diseases through our physiologically-relevant IN MATRICO™ platform. Our platform technology incorporates human tissue and disease-specific extracellular matrix substrates combined with clinically relevant data packages to enable drug candidates to be tested IN MATRICO™ to

Xylyx Bio collaboration reveals new insights into tumor drug resistance 04/05/2022

Our collaboration with Dr. Zeynep Madak-Erdogan's team at the University of Illinois has revealed differential responses to a drug in metastatic sites using our IN SITE™ Metastasis Kit.

https://www.prnewswire.com/news-releases/xylyx-bio-collaboration-reveals-new-insights-into-tumor-drug-resistance-301517042.html?tc=eml_cleartime

Xylyx Bio collaboration reveals new insights into tumor drug resistance /PRNewswire/ -- Xylyx Bio develops physiologic disease models that enable researchers to gain insights into tumor biology and evaluate the efficacy of drug...

11/29/2021

Seeking alternatives to ? Stock up with 20% off of TissueSpec® ECM Hydrogel kits using the promotional code: TISSUESPEC2021

Xylyx Bio, Inc. extracellular matrix hydrogels are specific to bone, intestine, liver, lung, and other tissues with minimal lot-to-lot variability and are compatible with conventional and advanced cell culture techniques!

11/01/2021

Visit our virtual booth at this year's Antifibrotic Drug Development Summit.

https://afdd-summit.com/xylyx-bio-virtual-booth/

10/26/2021

Join us on November 2 to learn about how our IN MATRICO platform can revolutionize anti-fibrotic drug discovery.

And visit our virtual booth at this years Antifibrotic Drug Development Summit: https://afdd-summit.com/xylyx-bio-virtual-booth/

Xylyx Bio Awarded $2.2M NIH SBIR Fast-Track Grant from National Heart, Lung, and Blood Institute 09/03/2021

Xylyx Bio Awarded $2.2M NIH SBIR Fast-Track Grant from NHLBI.

Read more here: https://www.prnewswire.com/news-releases/xylyx-bio-awarded-2-2m-nih-sbir-fast-track-grant-from-national-heart-lung-and-blood-institute-301367888.html?tc=eml_cleartime

Xylyx Bio Awarded $2.2M NIH SBIR Fast-Track Grant from National Heart, Lung, and Blood Institute /PRNewswire/ -- Xylyx Bio, Inc., a biotechnology company developing groundbreaking solutions for drug discovery and tissue modeling and repair, announced today...

Xylyx Bio partners with Inventia Life Science to develop tissue-specific, digitally-printed bioinks for drug discovery 09/01/2021

Xylyx Bio is excited to announce a partnership with to develop tissue-specific, digitally-printed bioinks for drug discovery.

Learn more here: https://www.prnewswire.com/news-releases/xylyx-bio-partners-with-inventia-life-science-to-develop-tissue-specific-digitally-printed-bioinks-for-drug-discovery-301366587.html?tc=eml_cleartime

Xylyx Bio partners with Inventia Life Science to develop tissue-specific, digitally-printed bioinks for drug discovery /PRNewswire/ -- Xylyx Bio, a New York-based leader in advanced biomaterials, and Inventia Life Science, a Sydney-based biotechnology company, today announced...

3D Cell Culture Media: Secret Sauce for Success 07/21/2021

Interested in learning more about cell culture media? Take a moment to read this recent blogpost where our Senior Research Scientist, Evelyn Aranda, provides her view on how to choose the right for your .

https://www.genengnews.com/topics/bioprocessing/3d-cell-culture-media-secret-sauce-for-success/

3D Cell Culture Media: Secret Sauce for Success The major difference between ordinary 2D or suspension cultures and 3D is the extracellular matrix, which holds the cells together and confers biological relevance.

06/10/2021

Assay provides a human fibrotic lung testing environment for , and .
Learn more about our services offerings here: https://xylyxbio.com/in-matrico-compound-testing-services/

06/02/2021

05/27/2021

Primary human hepatocytes cultured in thin hydrogels showed significantly higher expression of LDL receptor in ® Liver compared to cultured in .
Learn more about our liver ECM offerings here: https://shop.xylyxbio.com/products/liver

05/24/2021

Primary normal human bronchial epithelial cells in
® formed more organized, stratified luminal structures recapitulating the cellular
architecture of the human airway compared to .
Learn more about our products here: https://xylyxbio.com/products/

05/18/2021

Tune in today to learn more about our substrates and their use in .

05/13/2021

® Skin induces cell migration:
A375 cells show significantly different migration through transwell membrane (pores: 8 μm) to TissueSpec® Skin ECM Hydrogel in comparison to Matrigel and plastic (no ECM).

05/11/2021

cells (a) BT-549 and (b) T47-D in ® Bone, Liver, and Lung show differential responses in viability to or vehicle after 48 hours.

05/04/2021

® supports phenotype:
Primary human cultured in TissueSpec® Bone ECM Hydrogel show characteristic dendritic morphology after 1 hour in culture. Osteoblasts have higher alkaline phosphatase activity in TissueSpec® Bone ECM Hydrogel than in Matrigel and collagen I after 7 days in culture.
Learn more here:https://xylyxbio.com/wp-content/uploads/2020/04/Xylyx_TissueSpec%C2%AE-Bone-ECM-Hydrogel-Product-Datasheet.pdf

JAB Maui Burn & Wound Symposium Agenda 04/20/2021

Meet our CSO John O'Neill at the poster session on April 22nd!

JAB Maui Burn & Wound Symposium Agenda The JAB Maui Burn & Wound Symposium is an international conference that covers the latest advancements in wound healing, burn care, and infection control. Presentations are made by physicians, nurs...

ECM specialists Xylyx Bio launch skin care brand 04/14/2021

https://www.cosmeticsdesign.com/Article/2021/04/08/ECM-specialists-Xylyx-Bio-launch-skin-care-brand-VIVIQ

ECM specialists Xylyx Bio launch skin care brand Today, executives from Xylyx Bio announced the launch of VIVIQ Skin Health, a consumer brand that leverages proprietary ECM tech.

VIVIQ™ Skin Health Launches to Bring Clinical Benefits to Prestige Skincare 04/12/2021

We would like to share some exciting news! We have officially launched our brand VIVIQ Skin Health! Based on our ® Biotechnology, it is designed to bring clinic-worthy results to .
Please visit the website https://viviqskin.com/ to get a special promo!
https://www.prnewswire.com/news-releases/viviq-skin-health-launches-to-bring-clinical-benefits-to-prestige-skincare-301264643.html?tc=eml_cleartime

VIVIQ™ Skin Health Launches to Bring Clinical Benefits to Prestige Skincare /PRNewswire/ -- VIVIQ Skin Health, a prestige skincare brand, launched today with the world's first and only skincare product powered by Matrikynes®...

Extracellular Matrix: The Secret Sauce of 3D Cell Culture 04/06/2021

Our products were highlighted in today's editorial by on the importance of extracellular matrix in 3D cell culture!

Extracellular Matrix: The Secret Sauce of 3D Cell Culture ECM is the framework on which many advanced 3D cultures are built.

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Our Story

Just as the environment matters at the macro scale for plants and animals, it is essential at the micro scale for cells. Recognizing the importance of the native cellular microenvironment, Xylyx Bio is harnessing the power of tissue-specific extracellular matrix, the body’s native cell environment, for both drug discovery and tissue regeneration.

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760 Parkside Avenue
New York, NY
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