Genlantis Diagnostics

Researchers are trying antivirals widely used to treat HIV in hopes they might be able to fight the coronavirus as well



https://www.sciencemag.org/news/2020/01/can-anti-hiv-combination-or-other-existing-drugs-outwit-new-coronavirus

Can an anti-HIV combination or other existing drugs outwit the new coronavirus? Chinese scientists are testing widely used antivirals in patients in Wuhan, the epicenter of the outbreak

Vermont has been experiencing an upswing of both hepatitis A and B

https://www.sentinelsource.com/news/health/vermont-latest-state-to-see-a-spike-in-hepatitis-a/article_3ecca9da-aa08-54e0-8b58-353472b4b35f.html

Vermont latest state to see a spike in hepatitis A Vermont is now among 30 states to report a spike in hepatitis A cases since 2016, while New Hampshire is just starting to recover from its own outbreak last year.

According to experts, dengue has clearly become an all-season virus



https://lnkd.in/gvXdizT

Telangana: Surge in dengue numbers worries doctors | Hyderabad News - Times of India Just when the state health authorities had written off dengue as a threat and a dip in number of cases were being seen, the dengue spreading Aedes mos

The WHO estimates a massive shortage of 18 million health care workers by 2030. Thus creating a huge need for self-care intervention.

https://www.who.int/reproductivehealth/publications/self-care-interventions/en/

WHO consolidated guideline on self-care interventions for health: sexual and reproductive health and rights Self-care interventions are among the most promising and exciting new approaches to improve health and well-being, both from a health systems perspective and for people who use these interventions. The World Health Organization (WHO) uses the following working definition of self-care: Self-care is t...

Intellia's CRISPR Trial Delay Raises Questions About Immune Responses | BioSpace In its recent third-quarter report, Cambridge, Mass.-based Intellia Therapeutics indicated it is delaying its submission of an Investigational New Drug (IND) application until 2020, from late 2019.

Synthetic microorganisms allow scientists to study ancient evolutionary mysteries: Scientists use the tools of synthetic biology to engineer organisms similar to those thought to have lived billions of years ago Scientists have created microorganisms that may recapitulate key features of organisms thought to have lived billions of years ago.

Researchers have discovered how to slow aging: Natural product found to reduce the level of damaged cells in the body, caused by aging Previous research showed it was possible to reduce the burden of damaged cells, termed senescent cells, and extend lifespan and improve health, even when treatment was initiated late in life. They now have shown that treatment of aged mice with the natural product Fisetin, found in many fruits and v...

Kidney Transplant Success Improved by Swedish Biotech’s Drug There is hope for many patients on the kidney transplant waiting list, as a Swedish biotech’s lead candidate drug could help reduce rejections in kidney transplant patients. When given the drug candidate imlifidase before their kidney transplant in two Phase ...

Scientists have moved one step closer to RNA editing, which could be the next stage of CRISPR Researchers at the prestigious Salk Institute are reporting that they have managed to map the molecular structure of a CRISPR enzyme that could allow scientists to more precisely manipulate functions within cells. Over the past several years, CRISPR-Cas9 has seized the public imagination for its ab....

How tissues and organs are sculpted during embryogenesis Ever wondered how groups of cells managed to build your tissues and organs while you were just an embryo? Using state-of-the-art techniques he developed, researchers have cracked this longstanding mystery, revealing the astonishing innerworkings of how embryos are physically constructed.

Scientists identify protein that may have existed when life began: The primordial peptide may have appeared 4 billion years ago How did life arise on Earth? Researchers have found among the first and perhaps only hard evidence that simple protein catalysts -- essential for cells, the building blocks of life, to function -- may have existed when life began.

Found: A destructive mechanism that blocks the brain from knowing when to stop eating Researchers have uncovered a destructive mechanism at the molecular level that causes a well-known phenomenon associated with obesity: leptin resistance. They found that mice fed a high-fat diet produce an enzyme named MMP-2 that clips receptors for the hormone leptin from the surface of neuronal ce...

New genetic regulators of regeneration identified: Discovery could one day lead to new therapies to trigger regeneration in humans Scientists have discovered that genetic material in the cell that was previously thought to be 'junk' because of its apparent lack of function likely plays a part in regulating genetic circuits responsible for regeneration in highly regenerative animals. The discovery could one day lead to the devel...

This matrix delivers healing stem cells to injured elderly muscles: Muscular dystrophy patients could someday also benefit from this hydrogel successfully tested in mice Muscles of the elderly and of patients with Duchene muscular dystrophy have trouble regenerating. A new nanohydrogel with muscle stem cells has boosted muscle growth in mouse models while protecting the stem cells from immune reactions that usually weaken or destroy them.

Study challenges evolution of FOXP2 as human-specific language gene FOXP2, a gene implicated in affecting speech and language, is held up as a textbook example of positive selection on a human-specific trait. But in a new paper, researchers challenge this finding. Their analysis of genetic data from a diverse sample of modern people and Neanderthals saw no evidence....

Lung cell discovery opens new route for cystic fibrosis treatment | FierceBiotech Scientists already know cystic fibrosis is caused by mutations in the CFTR gene, but they didn’t know where expression of the gene is active. Now, two separate teams have discovered a rare cell type in airway tissue that appears to play a key role in the genetic disorder.

Scientists generate key life event in artificial mouse 'embryo' created from stem cells The creation of artificial embryos has moved a step forward after an international team of researchers used mouse stem cells to produce artificial embryo-like structures capable of 'gastrulation', a key step in the life of any embryo.

Scientists discover the world's oldest colors Scientists have discovered the oldest colors in the geological record, 1.1-billion-year-old bright pink pigments extracted from rocks deep beneath the Sahara desert in Africa.

Cell Line Validation in Biomanufacturing | GEN In biopharmaceutical manufacturing, cell line validation goes well beyond the verification of cell identity. It also encompasses the verification of purity, sterility, and functionality—all to meet regulatory demands.

Scientists develop proteins that self-assemble into supramolecular complexes Scientists have designed new proteins that can self-assemble into the complex structures underlying biological organisms, laying the groundwork for leading-edge applications in biotechnology. The researchers created and developed the proteins with a specific function and their method reveals a possi...

Virus-free CRISPR could mean faster, more precise gene editing for T-cell therapies | FierceBiotech A new electroporation-based CRISPR-Cas9 method eliminated viruses from the process and laid the groundwork for safer, more precise and more efficient gene editing for CAR-T cancer treatments and other cell therapies.

Bitcoin 2.0: How Blockchain Companies Will Help Us Protect Our Genomic Data Using genomic data and the blockchain network it is now possible to send anonymous genetic information around the world in the blink of an eye. Meet the companies that have sprung up over the last year that want to help ...

www.sciencedaily.com

The Challenges of Harmonizing Biomarker Data | GEN Pharmaceutical companies are turning to biomarkers in increasing numbers.

Century-Old Antarctic Algae Samples Are Helping Researchers Looking for an Alzheimer's Cure Examining old algae has helped create a baseline in efforts to cure neurodegenerative diseases.

Compound made inside human body stops viruses from replicating A team of researchers has identified the mode of action of viperin, a naturally occurring enzyme in humans and other mammals that is known to have antiviral effects on viruses such as West Nile, hepatitis C, rabies, and HIV. This discovery could allow researchers to develop a drug that could act as....

Microbe breaks 'universal' DNA rule by using two different translations: Scientists discover yeast that randomly translates DNA two different ways DNA is often referred to as the blueprint for life, however scientists have for the first time discovered a microbe that uses two different translations of the DNA code at random. This unexpected finding breaks what was thought to be a universal rule, since the proteins from this microbe cannot be f...

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Synthetic 'tissues' build themselves: Biologists program cells to self-organize into 3D-structures in a first step towards tissues that regrow and self-repair How do complex biological structures -- an eye, a hand, a brain -- emerge from a single fertilized egg? This is the fundamental question of developmental biology, and a mystery still being grappled with by scientists who hope to one day apply the same principles to heal damaged tissues or regrow ail...