ActiGraph

DPHARM 2024 is right around the corner! Will you be attending to learn more about the latest innovations to modernize clinical trials?

We hope you can join CEO, Jeremy Wyatt, and an impressive panel moderated on Wednesday, September 18th at 3:40pm -

“Advancing Scalability and Operationalizing Digital Endpoints in Clinical Trials”

The panel will discuss:
🛠️ How organizations operationalize endpoints in trials
🗃️ Digital measures in an integrated strategy program across multiple trials
⚖️ Measuring success & how this differs across primary, secondary, exploratory endpoints
📡 Staying up to date on ever-changing guidelines in this dynamic space

🗓️ Mark your calendars for Sept 25th and join us for a Digital Health Monthly roundtable webinar discussion on the recent FDA Digital Health Technology guidance.

Register here ➡️ https://hubs.la/Q02NG2sF0

We'll hear perspectives on the impact of the recommendations in this guidance and implications for the future of DHTs in clinical trials from panelist representing multiple industry perspectives, including -

🔘 Annie Saha, Digital Health Center of Excellence at FDA
🔘 Bert Hartog, Digital Medicine Society
🔘 Carrie Northcott, Pfizer
🔘 Nicholas Fountoulakis, RAC, Janssen Research & Development
🔘 Sylvain Zorman, PhD, ActiGraph

Digital Health Monthly: FDA DHT Guidance | ActiGraph Explore data-driven health insights with 'Digital Health Monthly' webinar series. Join expert panels to uncover digital health advancements. Register now!

Couldn't make it to our Digital Health Monthly webinar last week? 🤷 No problem!

▶️ You can watch, Beyond Weight Loss: Measuring Critical Health Outcomes in GLP-1 and Related Obesity Treatments, on-demand:
https://hubs.la/Q02NpjMH0

🚶‍♂️Dr. Glenn Gaesser reviewed data from his extensive research career as an exercise physiologist demonstrating the impact that physical activity and function have on health outcomes in people who are normal weight and overweight/obese, suggesting several measures of important health outcomes beyond weight loss.

🚶‍♀️Dr. Sylvain Zorman shared more information about the new DECODE-Obesity working group, aiming to develop wearable DHT-based measures of physical activity, physical function, and sleep with the goal of better informing trial design and health benefits of novel obesity treatments.

Digital Health Monthly: Obesity | ActiGraph Explore data-driven health insights with 'Digital Health Monthly' webinar series. Join expert panels to uncover digital health advancements. Watch now!

🎉 ActiGraph is looking forward to the European Respiratory Society Congress in Vienna next week to explore the latest advancements in respiratory science.

To learn more about how continuous, objective data from wearable DHTs can support your respiratory research, reach out to Jonathan Lake or click here to schedule a meeting 👉https://hubs.la/Q02N9GGS0

We’re excited to be included in Digital Medicine Society (DiMe)’s new 🔍 deep dive series, which provides more details around how the community uses the resources they provide to transform the landscape of digital health.

🔎 This article focuses on how the output of the DATAcc Nocturnal Scratch project, such as the patient survey, shared terminology, and collaborative insights, were key resources used when launching the DECODE Nocturnal Scratch working group.

Check out the full article below, and keep an eye out for more installments to come!
➡️https://hubs.la/Q02N4LwF0

Advancing dermatological digital measures using Nocturnal Scratch resources – Digital Medicine Society (DiMe) Check out DiMe's latest deep dive 👀

📣 Call for Abstracts! 📣 The ActiGraph Digital Data Summit 2025 will host a Scientific Poster Session, and we invite you to submit original research that involves the use of wearable digital health technologies (DHTs) by Oct 27.

For more details and to submit your application, visit: https://hubs.la/Q02MYdqK0

We look forward to seeing you February 10-12 in Pensacola Beach, FL for ADDS2025!

Scientific Poster Session Application | ADDS 2025 Apply now to participate in the ADDS 2025 scientific poster session!

📨 This is your invitation to join the Digital Health Monthly webinar this week!

The obesity treatment landscape has been changed considerably by GLP-1 weight management therapies. During the webinar, Dr. Glenn Gaesser and Dr. Sylvain Zorman will discuss important health outcomes beyond weight loss and how they can be measured in clinical trials to continue to advance obesity treatments as R&D activity in this field continues to grow.

📬 RSVP (register) here: https://hubs.la/Q02Mx7R10

Digital Health Monthly: Obesity | ActiGraph Explore data-driven health insights with 'Digital Health Monthly' webinar series. Join expert panels to uncover digital health advancements. Register now!

Don't delay, register today for September's special industry roundtable session of the Digital Health Monthly webinar series -

📍Navigating the FDA DHT Guidance: Perspectives from Across the Industry

✅https://hubs.la/Q02M3LYG0

Hear from multiple industry stakeholders joining the panel to discuss the practical implications of FDA’s final guidance on the use of Digital Health Technology (DHT) in clinical trials:
🔸Annie Saha, Digital Health Center of Excellence at FDA
🔸Carrie Northcott, Pfizer
🔸Nicholas Fountoulakis, RAC, Janssen Research & Development
🔸Bert Hartog, Digital Medicine Society
🔸Sylvain Zorman, PhD, ActiGraph

Digital Health Monthly: FDA DHT Guidance | ActiGraph Explore data-driven health insights with 'Digital Health Monthly' webinar series. Join expert panels to uncover digital health advancements. Register now!

We're excited to share our latest resource! 🎉

📚 The Patient-Focused Digital Measures Library 📚

We leverage information from the FDA's Patient-Focused Drug Development initiative to highlight opportunities for wearable DHTs to provide a patient-centric measure for use in clinical research. In the library table, we summarize for a variety of disease indications:

- Most Significant Symptoms reported by patients
- The relevant Meaningful Aspects of Health
- Candidate Digital Measures to assess these symptoms

➕ You can access individual Patient-Focused Digital Measure Reports for more details related to a specific disease, including how symptoms impact patients’ daily lives, and a description of candidate digital measures.

Visit the Library:
☑️ https://hubs.la/Q02Ltsn30

Read about the inspiration for this library:
👉 https://hubs.la/Q02Lt50m0

A New Resource to Help Advance Patient-Focused Drug Development with DHTs Introducing a new resource identifying relevant digital measures for clinical trials in specific disease indications based on the FDA Voice of the Patient Reports.

🔃 GLP-1 weight management therapies have dramatically changed the landscape of obesity treatment.

Register today and join our live discussion on August 28th at 12 PM ET to learn more about Measuring Critical Health Outcomes in Obesity Treatments -
📌 https://hubs.la/Q02L7BBR0

Dr. Glenn Gaesser will share research on the relationship between obesity and exercise physiology, and importance of physical fitness and activity as meaningful health outcomes beyond weight loss.

Dr. Sylvain Zorman will present details on the new DECODE-Obesity working group and applying data from wearable DHTs to better inform trial design and health benefits of novel obesity treatments.

✨ We hope you can join us!

Digital Health Monthly: Obesity | ActiGraph Explore data-driven health insights with 'Digital Health Monthly' webinar series. Join expert panels to uncover digital health advancements. Register now!

📣 Please join us live on August 28th at 12 PM ET for this month's session of ActiGraph's Digital Health Monthly scientific webinar series -

Beyond Weight Loss: Measuring Critical Health Outcomes in GLP-1 and Related Obesity Treatments

Register here ✨ https://hubs.la/Q02KqPng0 ✨

Dr. Glenn Gaesser and Dr. Sylvain Zorman will discuss important health outcomes beyond weight loss such as physical activity and physical functioning, and how wearable DHTs can help us capture this type of data to advance obesity treatments.

Digital Health Monthly: Obesity | ActiGraph Explore data-driven health insights with 'Digital Health Monthly' webinar series. Join expert panels to uncover digital health advancements. Register now!

🌍 Since the opening ceremony in Paris, the eyes of the world have been on the Olympic events. This inspired us to hold our own ActiGraph Olympics, where our teams designed their own flags 🚩, competed in multiple skill games 🎲, and stepped up for a step count challenge 👣

We’ve had a blast bringing together our international team to celebrate our unique skills and competitive spirits!

Can you guess any of the answers from our Emoji Code Breaking Challenge?

We are hiring! ActiGraph has a new career opportunity available within our sales team.

We are looking for a Sales Development Representative to assist in identifying and qualifying new sales opportunities within Pharmaceutical and Biotech companies and Contract Research Organizations (CROs).

Are you interested in contributing to the growing field of wearable technology and digital measures that are used to improve clinical trials and help life-changing treatments reach patients faster? Apply today to join us as we pioneer the digital transformation of clinical research! 👉 https://hubs.la/Q02K0J5M0

Check out this 🆕 recap of our Wearable DHT 101 Digital Health Monthly session!

Christine Guo walks through the journey of research and evidence generation in clinical trials, highlighting the steps from technical specification to regulatory acceptance that include DHTs to help give a wholistic view of this process to clinical trialists 🛣️

Read here: https://hubs.la/Q02JLJKM0

Wearable DHT 101: Foundations for Use in Regulated Clinical Trials We review the definition of wearable DHTs, the benefits of continuous sensor data, the scope of wearable use in regulated clinical trials.

Now available on-demand! In this informative session of Digital Health Monthly, our expert guests, Fatta Nahab and Karen Krygier, share -

⏩ An overview of Parkinson’s Disease symptoms & the need for more precise clinical measures

⏩ How more frequent measures using digital health technologies can improve signal to noise

⏩ Strategic considerations for including digital clinical outcomes in PD drug development

⏩ Specific use-cases of wearable DHTs in PD clinical trials

Watch here >> https://hubs.la/Q02JzVLV0

*To learn more about incorporating digital measures into your upcoming PD study, schedule a meeting with ActiGraph and PKG Health at the 2024 International Congress of Parkinson’s Disease and Movement Disorders in Sept!
👉 https://hubs.la/Q02JzhfR0

Digital Health Monthly: Parkinson's Disease | ActiGraph Explore data-driven health insights with 'Digital Health Monthly' webinar series. Join expert panels to uncover digital health advancements. Watch now!

Understanding how mobility and gait features are affected in Multiple Sclerosis patients can help researchers -
📈 track disease progression and severity,
🏃‍♀️ inform the impact MS has on quality of life, and
🔬 assess the effectiveness of new treatments and rehabilitation therapies.

Learn about the ActiGraph DEAR Grant collaboration with Dr. Alon Kalron at Tel-Aviv University assessing the validity of wearable data to help fill this measurement gap: https://hubs.la/Q02HJSjL0

Gait Measurement in Multiple Sclerosis Using Wearable Sensors | DEAR Grant Profile Dr. Alon Kalron, a recipient of the DEAR Grant, is working with ActiGraph to validate digital measures of gait in patients with multiple sclerosis.

🌡️ As competition in the obesity treatment pharmaceutical R&D pipeline continues to grow -

The need for evidence generation of health benefits beyond weight loss, as well as improved clinical trial design, is becoming critical for program success 🎯

📒Review our latest Digital Endpoint Guide to learn more about how continuous, objective wearable data can provide valuable insights to researchers and drug developers aiming to understand treatment effectiveness in conditions like obesity, type 2 diabetes, and NASH

https://hubs.la/Q02HJSkf0

Digital Endpoints Series: Obesity and Related Metabolic Disorders This indication guide shows how wearables can provide new clinical insights for patients with metabolic conditions using real-world data.

⌚🔁⌚ Which device is the right choice for my study?

To help researchers get started answering this question, we’ve created a table that provides information around key questions to consider when deciding between a medical-grade wearable or a consumer wearable device.

Read more here ⏩

Medical-Grade or Consumer Wearable? How to Choose A list of questions for researchers to help them decide if a medical-grade wearable or consumer wearable device is the right choice for their study.

New insights from multisensor wearable devices can be transformative for clinical research 🔬 But there's a crucial element to realizing this potential that often gets overlooked...

⚡ Battery Life ⚡

The need to frequently charge a wearable device can be burdensome to patients, which may put the quality/completeness of study data at risk. What have we done to extend the battery life in the multisensor ActiGraph LEAP device?

🔂 Duty Cycles – activates sensor(s) at specific times during the day

⏬ Event-based Data Capture – activates sensor(s) after participants press a button

These features allow researchers to collect multisensor data when needed in their study, while also prolonging battery life to enhance usability.

Learn more about these new features here: https://hubs.la/Q02GZZgs0

Flexible Features in Fit-For-Purpose Wearable Digital Health Technology ActiGraph introduces duty cycles and event-based data capture features for ActiGraph LEAP to create a device fit-for-purpose for clinical research.

Outsourcing-Pharma’s Liza Laws talks with ActiGraph’s CSO Christine Guo about the transformative potential of wearables in providing accurate, real-world sleep data 💤

Check out the full article to learn more about how this type of data can improve patient outcomes ⏩

https://hubs.la/Q02GysWN0

Advancing sleep health: Wearable technologies revolutionize clinical trials and patient care Christine Guo, chief scientific officer at ActiGraph, discusses the pivotal role of wearable health technologies in revolutionizing sleep health measurement within clinical trials.

🔀 We're excited to announce the integration of Mobilise-D algorithms for digital mobility outcomes into our CentrePoint Cloud Platform!

Click here to read more 🔷 https://hubs.la/Q02GghVr0

During the multi-year Mobilise-D project, 🏃 wearable DHTs were used to collect mobility data in healthy and disease populations to generate validated digital mobility measures to advance research in this important area of health.

🔬 Researchers can now incorporate these measures into their study using the most up-to-date and clinically validated Mobilise-D algorithms supported by ActiGraph’s state-of-the-art wearable device hardware and innovative software platform.

ActiGraph Announces Integration of Mobilise-D Algorithms in CentrePoint Platform ActiGraph announces the integration of Mobilise-D algorithms for digital mobility outcomes into CentrePoint Cloud Platform and new lumbar accessories.

🔦The recent success of GLP-1 receptor agonists drugs in achieving weight loss has put obesity into the spotlight as a chronic disease that requires comprehensive management.

Despite initial positive outcomes, the long-term benefits of these obesity treatments are still under scrutiny. 🔎

In our latest white paper, we dive into some of the open questions related to new obesity treatments, and discuss future opportunities for drug developers to provide more targeted and effective treatments for patients by -

🎯 developing evidence-based guidelines for the physical activity that accompanies pharmaceutical treatments

🎯 capturing low-burden and objective assessments of physical function and sleep quality that are often negatively impacted by obesity

Read more here 📒 https://hubs.la/Q02G4dR60

Looking Beyond Weight Loss in the Obesity Pandemic: What’s Next? In this ActiGraph white paper, we review the promising developments and challenges in the rapidly evolving landscape of obesity treatments.

🔍 DHTs bring many potential benefits to clinical research, but there are still technical challenges to overcome for DHTs to be used in research across populations, including pediatric participants.

🏃‍♂️ During a recent session of Digital Health Monthly, Dr. Junrui Di joined Dr. Rakesh Pilkar to review the results of the study, Measuring Activity and Gait in Children with DHTs, and shed light on the intricacies of this project.

📔 Read the recap here: https://hubs.la/Q02F26hm0

Measuring Activity and Gait in Children with DHTs We review the data from a study demonstrating that DHTs can reliably and accurately capture physical activity and gait information in children.

Couldn’t join us for this week’s Digital Health Monthly webinar? No problem! DHT 101 for Clinical Research is now available on-demand.
🎬 https://hubs.la/Q02DBCh60

Watch now to learn more about the use of wearable-derived data as endpoints in clinical trials, addressing important points along the journey including -
☑️ The definition of DHT
☑️ Common uses in regulated trials
☑️ Key validation evidence
☑️ Operational deployment considerations

🙏 Thank you to everyone who visited us at ! It was inspiring to connect with experts in ambulatory monitoring and movement tracking. Let's continue to innovate and improve health outcomes together! Let’s reconnect: https://hubs.la/Q02D2x2r0

The life sciences community faces many challenges. But after DIA 2024, it’s equally evident that collaborative efforts are yielding solutions.

Over the last several days, we’ve had the opportunity to share more about the impact of our digital health technologies in clinical research and the pleasure of connecting with so many people working hard to make a difference. Together, we will continue to enhance healthcare around the world. 💙

ActiGraph is thrilled to be at ICAMPAM 2024! Stop by our stand to discover how we're contributing to the field of ambulatory monitoring of physical activity and movement. Let's exchange ideas and insights! 🤝

🔜⏲️ The countdown is on…Get ready for Panagora Pharma 7th Annual Digital Biomarkers in Clinical Trials at Roche headquarters in Basel on June 26!

Be sure to stop by our stand and meet the ActiGraph team - Jodie Lyons, Jonathan Lake, John Bailey - and please join us for Jeremy Wyatt's presentation to learn more about The Digital Endpoint Collaboration to accelerate Outcome DEvelopment, (DECODE)!

We’d love to discuss how we can work together to accelerate adoption of digital health technology for more effective and patient-centric clinical trials!

Introducing two new features to support flexibility and usability in studies using ActiGraph LEAP devices -

✅ Duty Cycles

✅ Event-Based Data Capture

Read more details here: https://hubs.la/Q02CgzQj0

👉 These new features will improve usability at the study team, site, and participant level, increasing flexibility and further developing ActiGraph LEAP as a fit-for-purpose, wearable DHT to help uncover the unique clinical insights that are possible with multisensor data.

Flexible Features in Fit-For-Purpose Wearable Digital Health Technology ActiGraph introduces duty cycles and event-based data capture features for ActiGraph LEAP to create a device fit-for-purpose for clinical research.

DIA 2024 is underway in San Diego, and we want to see you! ⛱ Visit booth #2216 to meet some of the team, explore innovative solutions, and be part of the conversation! Let's reimagine processes together!

✅Don’t forget to submit your vote for the ActiGraph LEAP in the DIA Best in Show Awards!