Targeted Intraoperative Radiotherapy

Learn about Targeted Intraoperative Radiotherapy (TARGIT), a single-dose radiation treatment given at the time of lumpectomy for early stage breast cancer.

Targeted Intraoperative Radiotherapy (TARGIT) of the breast is a form of breast irradiation that is administered as a single treatment at the time of lumpectomy. TARGIT is considered a practical and safe alternative to standard breast radiation therapy that is commonly given after lumpectomy on a daily basis for approximately 6 Weeks. As a result, TARGIT makes breast conservation and breast radiot

(TIME SENSITIVE) From Dennis R. Holmes, MD, FACS: "A Freedom Worth Fighting For" 07/01/2023

https://conta.cc/3CTAGEX

(TIME SENSITIVE) From Dennis R. Holmes, MD, FACS: "A Freedom Worth Fighting For" L.A. Breast Chronicles July 1, 2023 A FREEDOM WORTH FIGHTING FOR I really need your help. I’m looking for women who have received targeted intraoperative radiotherapy (TARGIT) (see above image) for

Happy New Year's Update from Dennis R. Holmes, M.D., FACS 01/02/2023

Happy New Year!

Perhaps you've noticed that I haven't been keeping up with regular postings but it's not because I've not been up to my usual activities. If you are interest in seeing what I have been up to, check out my 2022 year in review and 2023 year in preview: https://conta.cc/3G1gguI Wishing you a great year ahead!

Happy New Year's Update from Dennis R. Holmes, M.D., FACS L.A. Breast Chronicles 2022 in Review 2023 in Preview January 1, 2023 Happy New Year! It's been awhile since the last installment of L.A. Breast Chronicles, but it's not because there haven't been ne

Breast Cancer Q&A Webinar 11-20-2021 11/21/2021

Public
https://youtu.be/cXJ5Qp2pxaA
Breast Cancer Q&A Webinar 11-20-2021

Breast Cancer Q&A Webinar 11-20-2021 Dr. Holmes is interviewed by patient advocate, Sharon Merritt, presenting questions submitted by other women.

Welcome! You are invited to join a meeting: Breast Cancer Q & A Webinar. After registering, you will receive a confirmation email about joining the meeting. 11/15/2021

Join us for another breast cancer Q&A with Dr. Dennis Holmes Saturday, November 20, 2021 from 12:00-1:30 pm PST where he will be answering questions regarding breast cancer cryoablation, surgery, radiation, and more.

Register in advance for this meeting:
https://us02web.zoom.us/meeting/register/tZAvceCvrj0jGtKMg6XhxULTPVbQAA6HShZn

After registering, you will receive a confirmation email containing information about joining the meeting.

Welcome! You are invited to join a meeting: Breast Cancer Q & A Webinar. After registering, you will receive a confirmation email about joining the meeting. Welcome! You are invited to join a meeting: Breast Cancer Q & A Webinar. After registering, you will receive a confirmation email about joining the meeting.

10/20/2021

Dr. Holmes quotes on article about intraoperative radiotherapy.

https://www.crescentavalleyweekly.com/news/10/14/2021/a-targited-treatment-for-breast-cancer/

VIRTUAL: 'One-shot' radiotherapy safer and as effective for treating breast cancer as longer course 10/12/2021

'One-shot' radiotherapy safer and as effective for treating breast cancer as longer course

https://www.ucl.ac.uk/medical-sciences/events/2021/oct/virtual-one-shot-radiotherapy-safer-and-effective-treating-breast-cancer-longer

This is a public lecture - open to all, and free - please register.

VIRTUAL: 'One-shot' radiotherapy safer and as effective for treating

The evolution of a patient centred treatment from an idea to worldwide adoption

VIRTUAL: 'One-shot' radiotherapy safer and as effective for treating breast cancer as longer course The evolution of a patient centred treatment from an idea to worldwide adoption

Long term survival and local control outcomes from single dose targeted intraoperative radiotherapy during lumpectomy (TARGIT-IORT) for early breast cancer: TARGIT-A randomised clinical trial 08/02/2021

https://bepartofresearch.nihr.ac.uk/Articles/Health-research-breakthroughs/

TARGIT IORT Named one of the Top Five Health Research Breakthroughs in the last 12 Months

Dr. Holmes was a co-investigator in this research and co-author of the publication: https://www.bmj.com/content/370/bmj.m2836

Long term survival and local control outcomes from single dose targeted intraoperative radiotherapy during lumpectomy (TARGIT-IORT) for early breast cancer: TARGIT-A randomised clinical trial Objective To determine whether risk adapted intraoperative radiotherapy, delivered as a single dose during lumpectomy, can effectively replace postoperative whole breast external beam radiotherapy for early breast cancer. Design Prospective, open label, randomised controlled clinical trial. Setting....

Support Helen Rey Breast Cancer Research Fund by shopping at AmazonSmile. 07/27/2021

Join me in supporting the Helen Rey Breast Cancer Research Foundation's efforts to reduce the burden of breast cancer care, including research on cryoablation and intraoperative radiotherapy. https://helenreybreastcancerfoundation.com
For every Amazon purchase at AmazonSmile, Amazon will make a small donation to support the Helen Rey Foundation.
https://smile.amazon.com/ch/81-4236238

Support Helen Rey Breast Cancer Research Fund by shopping at AmazonSmile. When you shop at AmazonSmile, Amazon will donate to Helen Rey Breast Cancer Research Fund. Support us every time you shop.

Welcome! You are invited to join a meeting: Breast Cancer Q & A Webinar. After registering, you will receive a confirmation email about joining the meeting. 07/14/2021

https://us02web.zoom.us/meeting/register/tZYudO6prjMtGd2YcLrY3Up1SgLDAYFGLQiF

Welcome! You are invited to join a meeting: Breast Cancer Q & A Webinar. After registering, you will receive a confirmation email about joining the meeting. Welcome! You are invited to join a meeting: Breast Cancer Q & A Webinar. After registering, you will receive a confirmation email about joining the meeting.

07/12/2021

Join us from 12:00 pm - 1:30 pm PST on JULY 17, 2021 for the next installment of a bimonthly Question and Answer webinar sponsored by the Helen Rey Breast Cancer Research Foundation. Watch a live interview of Dr. Holmes by patient advocate, Sharon Merritt. Also find out the latest about the FROST Trial and the upcoming clinical trial of cryoablation of DCIS.

Save the date for future Webinars:
September 18, 2021
November 20, 2021

Breast Cancer Q&A Webinar 05/11/2021

DATE CORRECTION: Join Us For Our Next Breast Cancer Q & A Webinar

Join us from 12:00 pm - 1:30 pm on MAY 15, 2021 for the next installment of a bimonthly Question and Answer webinar sponsored by the Helen Rey Breast Cancer Research Foundation. Receive live answers to your breast cancer questions about breast cancer screening, diagnosis, surgery, radiation, and cryoablation, including a detailed report of the Ice3 Trial.

You may submit questions in advance: Submit your question

Also save the date for future webinars: https://docs.google.com/forms/d/e/1FAIpQLSd0e9BiNrIl23oG_S2XWmRX1La-VMfh9Z2Rw3WcgxO_a6C1NA/viewform

July 17, 2021
September 18, 2021
November 20, 2021

Breast Cancer Q&A Webinar by Dennis R. Holmes, M.D., F.A.C.S. Sponsored by the Helen Rey Breast Cancer Research Foundation: https://helenreybreastcancerfoundation.com Please submit a maximum of 3 questions to be answered during Dr. Holmes's next live Breast Cancer Q&A Webinar on May 15, 2021 from 12:00pm-1:30pm. Save the dat...

Latest Update on Breast Cancer from Dennis R. Holmes, M.D. 05/05/2021

https://conta.cc/3un8Bjf

Latest Update on Breast Cancer from Dennis R. Holmes, M.D. L.A. Breast Chronicles Breast Health News ....That Can't Be Missed May 1, 2021 Mission Statement: The principles of breast health care are constantly evolving. The mission of this E-newsletter is to

Breast Cancer Question and Answer (January 16, 2021) 01/18/2021

Breast Cancer Q & A Webinar (January 16, 2021). In case you missed the most recent webinar, you can view a recording of the webinar online: https://www.youtube.com/watch?v=zIHWHn1tbqQ

Save the date for future Breast Cancer Question and Answer webinars:

March 20, 2021
May 15, 2021
July 17, 2021
September 18, 2021
November 20, 2021

Sponsored by the Helen Rey Breast Cancer Research Foundation. https://helenreybreastcancerfoundation.com

Breast Cancer Question and Answer (January 16, 2021) Watch our most recent Breast Cancer Question and Answer Webinar by Dr. Dennis Holmes, sponsored by the Helen Rey Breast Cancer Research Foundation. https://h...

01/16/2021

Join Us TOMORROW For Our Upcoming Breast Cancer Q & A Webinar

Join Dr. Dennis Holmes from 12:00 pm - 1:30 pm on January 16, 2021 for the second installment of a bimonthly Question and Answer webinar sponsored by the Helen Rey Breast Cancer Research Foundation. Receive live answers to your breast cancer questions about breast cancer screening, diagnosis, surgery, radiation, and cryoablation.
You may submit questions in advance: https://docs.google.com/.../1FAIpQLSe13iQXEo4.../viewform...
Also save the date for future webinars:
March 20, 2021
May 15, 2021
July 17, 2021
September 18, 2021
November 20, 2021

Not Found

Video Conferencing, Web Conferencing, Webinars, Screen Sharing 11/20/2020

Join Us For A Breast Cancer Q & A Webinar

Join Dr. Holmes at Noon on November 21, 2020 for the first installment of a bimonthly Question and Answer webinar. Receive live answers to your breast cancer questions with emphasis on breast surgery, cryoablation, and radiation-related questions.

Topic: Breast Cancer Q&A Webinar
Time: Nov 21, 2020 12:00-1:30 PM Pacific Time (US and Canada)

Join Zoom Meeting
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Latest News on Breast Cancer from Dennis R. Holmes, M.D. 10/31/2020

https://myemail.constantcontact.com/Latest-News-on-Breast-Cancer-from-Dennis-R--Holmes--M-D-.html?soid=1129698694259&aid=sfZ6ib_-laE

Latest News on Breast Cancer from Dennis R. Holmes, M.D. L.A. Breast Chronicles Breast Health News ....That Can't Be Missed October 26, 2020 Mission Statement: The principles of breast health care are constantly evolving. The mission of this E-newsletter i

Helen Rey Breast Cancer Research Foundation Annual Patient Appreciation 10/17/2020

https://youtu.be/RYvrKkIS5uE

Watch the annual Helen Rey Breast Cancer Research Foundation annual patient appreciation presentation. Due to COVID-19, this year’s event took place on October 3, 2020 as a webinar. The Helen Rey Breast Cancer Research Foundation is a 501(c)(3) non-profit research organization that supports Dr. Holmes's breast cancer research activities.

Learn more about recently complete, ongoing, and upcoming breast cancer clinical trials, and other breast cancer advancements.

Helen Rey Breast Cancer Research Foundation Annual Patient Appreciation Watch the annual Helen Rey Breast Cancer Research Foundation annual patient appreciation presentation. Due to COVID-19, this year’s event took place on Octob...

Join us for a special occasion 09/27/2020

https://conta.cc/33oA3AP

Join us for a special occasion Save The Date Saturday, October 3, 2020, 12:00 pm-1:30 pm Join us for the Helen Rey Breast Cancer Research Foundation annual patient appreciation event. Join us to learn more about intraoperative rad

Join us for a special occasion 09/13/2020

https://conta.cc/3iuSn1z

Join us for a special occasion Save The Date Saturday, October 3, 2020, 12:00 pm-1:30 pm PST Join us for the Helen Rey Breast Cancer Research Foundation annual patient appreciation event. Join us to learn more about intraoperative

Long term survival and local control outcomes from single dose targeted intraoperative radiotherapy during lumpectomy (TARGIT-IORT) for early breast cancer: TARGIT-A randomised clinical trial 08/20/2020

I am pleased to share with you the long-term results of the TARGIT-A Trial comparing partial breast single fraction targeted intraoperative radiotherapy (IORT) to 3-6 week post-operative whole breast radiotherapy, demonstrating equivalent long-term outcomes. The paper was published today in the British Journal of Medicine.

Recognizing the potential of IORT, I started performing targeted IORT in 2006 as only the second U.S. co-investigator in this 2,298 subject multicenter, international RCT. These clinical trial results have been a long time coming. It’s been a privilege to participate in this trial and co-author this publication as well as participate in or lead multiple other targeted IORT-related publications/clinical trials, several of which are ongoing.

The TARGIT-A trial is largely responsible for establishing IORT as a standard of care option for early stage breast cancer in the U.S. IORT is now covered by Medicare and most health plans—the result of a decade-long advocacy effort. In addition to being efficacious, separate publications have shown targeted IORT to be associated with fewer side effects, improved quality of life, and reduced healthcare cost compared to whole breast radiotherapy.

https://www.bmj.com/content/370/bmj.m2836

Long term survival and local control outcomes from single dose targeted intraoperative radiotherapy during lumpectomy (TARGIT-IORT) for early breast cancer: TARGIT-A randomised clinical trial Objective To determine whether risk adapted intraoperative radiotherapy, delivered as a single dose during lumpectomy, can effectively replace postoperative whole breast external beam radiotherapy for early breast cancer. Design Prospective, open label, randomised controlled clinical trial. Setting....

Single-dose technique transforms breast cancer treatment 12/06/2019

Cast Your Vote in Favor Of Intraoperative Radiotherapy (Vote for this story)
https://www.ucl.ac.uk/made-at-ucl/stories/single-dose-technique-transforms-breast-cancer-treatment

Single-dose technique transforms breast cancer treatment Research at UCL has transformed the treatment of breast cancer, the most common cancer in women, using innovative one-off targeted intraoperative radiation therapy (TARGIT IORT). This new treatment avoids the burden of a three- to six-week course of postoperative radiotherapy.

Dr. Holmes on Insight TV 11/21/2019

https://www.youtube.com/watch?v=jfeYapwlyno

Dr. Holmes on Insight TV Dr. Holmes discusses breast cancer on Insight TV

Just Diagnosed with Breast Cancer: Now What? | Susan G. Komen® 10/10/2019

https://ww5.komen.org/Blog/Just-Diagnosed-with-Breast-Cancer--Now-What-/
by Dennis R. Holmes, MD, FACS

Just Diagnosed with Breast Cancer: Now What? | Susan G. Komen® Few women (or men) are truly prepared to receive a breast cancer diagnosis. Knowing what to ask your doctor is a challenge for the newly diagnosed. The challenge is made even greater by ongoing improvements in how we manage breast cancer. The following list of questions will help you get off to a gr...

Photos from Targeted Intraoperative Radiotherapy's post 04/29/2019

Check out the latest edition of the L.A. Breast Chronicles!

Breast Health News...That Can't Be Missed!

This weeks topic for Hereditary Breast Cancers: A Story of Missed Opportunities

https://www.drholmesmd.com/contents/spotlight/breast-chronicles-newsletters-patients

Breast Cryoablation (Breast Tumor Freezing) 04/22/2019

Watch New Video showing breast cryoablation or breast tumor freezing performed by Dr. Holmes!

https://www.youtube.com/watch?v=RDUjoIJsaL8

Breast Cryoablation (Breast Tumor Freezing) Cryoablation or Tumor Freezing is an office-based treatment for breast cancer that involve insertion of a freezing needle or cryoprobe under local anesthesia...

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