Open Genomes Foundation

Exploring the lung microbiome’s role in disease Unusual microbial communities in a person’s lower airways could influence the onset and progression of lung cancer and other conditions, and might point the way to therapies.

New prototype therapy may repair IPF lung scarring by regenerating... Researchers developed NZ-97, an inhalable drug that stimulates the growth of stem cells in the lungs, potentially repairing scarring in IPF.

Discovery of DNA repair mechanism advances understanding of how human cells stay healthy Researchers at the University of Toronto have discovered a DNA repair mechanism that advances understanding of how human cells stay healthy, and which could lead to new treatments for cancer and premature aging.

Two lifeforms merge in once-in-a-billion-years evolutionary event Last time this happened, Earth got plants.

Brain’s Evolutionary Explosion Linked to Ancient Retrovirus Infection A new study has unraveled a mystery that is key to understanding the course of human and animal evolution. A team of genetic researchers from Altos

‘The situation has become appalling’: fake scientific papers push research credibility to crisis point Last year, 10,000 sham papers had to be retracted by academic journals, but experts think this is just the tip of the iceberg

New Discovery Brings Nearly Dead Plants Back to Life Discovery brings nearly dead plants back to life. Scientists have been aware of a specific organelle in plant cells for more than a hundred years. However, UC Riverside scientists have only now discovered the organelle’s key role in aging. The researchers initially set out to understand more gen

Immune cells linked to allergies can kill cancer The newly discovered cancer-killing abilities of a type of immune cell linked to allergies suggests it could be a new immunotherapy.

Cells Across the Body Talk to Each Other About Aging When mitochondria stop communicating, the biological clock starts winding down.

Scientists Destroy 99% of Cancer Cells in The Lab Using Vibrating Molecules Scientists have discovered a new way to destroy cancer cells.

Accurate detection of identity-by-descent segments in human ancient DNA - Nature Genetics ancIBD identifies identity-by-descent regions in ancient DNA using a hidden Markov model optimized for these low-coverage data. Analysis of 4,248 individuals demonstrates that ancIBD can identify up to sixth-degree relatives and provides genealogical insights into ancient populations.

Australian Indigenous genomes are highly diverse and unlike those anywhere else Nature - In collecting genomic data for Indigenous Australians, scientists hope to expand knowledge of human genetic diversity and improve health for this group.

New proteins, better batteries: Scientists are using AI to speed up discoveries New artificial intelligence tools are being rapidly developed across the sciences. They may not be able to solve every problem, but in some cases, they're shortening the time to new breakthroughs.

In first, archaeologists extract DNA of ancient Israelites ***

Scientists Discover a Completely New Type of Enzyme That Helps Fight Genomic Parasites Professor René Ketting's team at the Institute of Molecular Biology (IMB) in Mainz, Germany, along with Dr. Sebastian Falk's group at the Max Perutz Labs in Vienna, Austria, have discovered a new enzyme, PUCH, which plays a key role in preventing the spread of parasitic DNA in our genomes. This bre...

https://www.euronews.com/next/2023/08/26/german-scientists-make-a-major-discovery-that-could-slow-down-the-ageing-process

Scientists discover way to potentially slow down ageing in humans A new study from Germany has potentially found the answers to time-old questions: what drives ageing and what can we do to reverse it?

Neurodegenerative Disease and the NLRP3 Inflammasome The prevalence of neurodegenerative disease has increased significantly in recent years, and with a rapidly aging global population, this trend is expected to continue. These diseases are characterised by a progressive neuronal loss in the brain or peripheral nervous system, and generally involve pr...

Scientists Discover New Promising Target for Alzheimer’s Disease Treatment Levels of the TRIM11 protein were found to be reduced in models of Alzheimer's disease, according to new research from Penn Medicine. The study suggests that restoring the protein might improve cognitive and motor function. New research from the Perelman School of Medicine at the University of Pe

Gut microbes may warn of Alzheimer’s disease long before first symptoms begin What if the microbes in your gut could act as an early warning system, alerting you that you could be developing Alzheimer’s disease?

Healing Power of Light: Biomimetic Materials Pulsed With Low-Energy Blue Light Can Reshape Damaged Corneas A new study reveals that biomimetic materials, when pulsed with low-energy blue light, can reshape damaged corneas, including increasing their thickness. The findings have the potential to affect millions of people. A team of University of Ottawa researchers and their collaborators have uncovered

City of Hope scientists develop targeted chemotherapy able to kill all solid tumors in preclinical research /PRNewswire/ -- Researchers at City of Hope, one of the largest cancer research and treatment organizations in the United States, today published a new study...

Genetics may explain why some people are more likely to participate in genetic studies Why do some people take part in genetic studies while others do not? The answer may lie within our genetic makeup.

Scientists Identify a Single Genetic Variant That Makes MS More Severe Scientists have discovered a genetic variant linked with multiple sclerosis becoming more debilitating over time, in research hailed as a first step towards a new drug.

What could the world of microproteins have to offer? Researchers are uncovering thousands of short proteins that could lead to a treasure trove of new biology and drugs

Could Octopuses Arm the Field of Therapeutic RNA Editing? Octopuses use RNA editing to rapidly respond to environmental temperature changes. The finding may influence RNA editing therapeutics in humans.

Stem Cell Breakthrough: A Potential Cure for Baldness - Neuroscience News These findings indicate the potential for stimulating hair growth by manipulating cell mechanics.

Higher prenatal testosterone exposure is linked to Machiavellianism and psychopathy, study suggests New research provides evidence that some aspects of the Dark Triad of personality are linked to markers of prenatal testosterone exposure. The findings, published in Biological Psychology, shed light on the relationship between biological processes and personality development. ...

Nitric oxide levels found to have reversible causative role in autism spectrum disorder in a mouse model Researchers at the Hebrew University of Jerusalem and the University of Haifa in Israel have discovered that production of nitric oxide in the brain correlates with autistic symptoms. In their paper, "The NO Answer for Autism Spectrum Disorder," published in Advanced Science, the researchers describ...

First-of-Its-Kind Gene Therapy Can Be Applied to Skin Instead of Injected Dubbed Vyjuvek, the FDA-approved gene therapy directly delivers healthy copies of a mutated gene onto damaged skin.

Clearing Out the Trash – Stem Cells’ Battle Against Aging Scientists at UC San Diego have discovered that stem cells' unique method of discarding misfolded proteins could hold the key to preserving long-term health and avoiding illness. As humans continue their search for the fountain of youth, stem cells keep emerging as a key player in the